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公开(公告)号:EP2311877A2
公开(公告)日:2011-04-20
申请号:EP10011773.8
申请日:2006-11-24
申请人: Ganymed Pharmaceuticals AG , Johannes Gutenberg-Universität Mainz, vertreten durch den Präsidenten
发明人: Sahin, Ugur , Türeci, Özlem , Usener, Dirk , Fritz, Stefan , Uherek, Christoph , Brandenburg, Gunda , Geppert, Harald-Gerhard , Schröder, Anja Kristina , Thiel, Philippe
IPC分类号: C07K16/30 , A61K39/395 , A61P35/00 , C12N5/12 , A61K47/48
CPC分类号: C07K16/18 , A61K39/3955 , A61K45/06 , A61K47/6803 , A61K47/6807 , A61K47/6809 , A61K47/6813 , A61K47/6821 , A61K47/6823 , A61K47/6829 , A61K47/6851 , A61K47/6859 , A61K47/6863 , A61K47/6869 , A61K51/1063 , A61K2039/505 , C07K16/28 , C07K16/3046 , C07K2317/14 , C07K2317/24 , C07K2317/51 , C07K2317/515 , C07K2317/56 , C07K2317/565 , C07K2317/73 , C07K2317/732 , C07K2317/734 , C07K2317/76
摘要: The present invention provides antibodies useful as therapeutics for treating and/or preventing diseases associated with cells expressing CLD18, including tumor-related diseases such as gastric cancer, esophageal cancer, pancreatic cancer, lung cancer, ovarian cancer, colon cancer, hepatic cancer, head-neck cancer, and cancer of the gallbladder.
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12.Monoclonal antibodies against claudin-18 for treatment of cancer 审中-公开
标题翻译: Monoklonaleantikörpergegen claudin-18 zur behandlung von krebs公开(公告)号:EP2295469A2
公开(公告)日:2011-03-16
申请号:EP10011774.6
申请日:2006-11-24
申请人: Ganymed Pharmaceuticals AG , Johannes Gutenberg-Universität Mainz, vertreten durch den Präsidenten
发明人: Sahin, Ugur , Türeci, Özlem , Usener, Dirk , Fritz, Stefan , Uherek, Christoph , Brandenburg, Gunda , Geppert, Harald-Gerhard , Schröder, Anja Kristina , Thiel, Philippe
IPC分类号: C07K16/30 , A61K39/395 , A61P35/00 , C12N5/12 , A61K47/48
CPC分类号: C07K16/18 , A61K39/3955 , A61K45/06 , A61K47/6803 , A61K47/6807 , A61K47/6809 , A61K47/6813 , A61K47/6821 , A61K47/6823 , A61K47/6829 , A61K47/6851 , A61K47/6859 , A61K47/6863 , A61K47/6869 , A61K51/1063 , A61K2039/505 , C07K16/28 , C07K16/3046 , C07K2317/14 , C07K2317/24 , C07K2317/51 , C07K2317/515 , C07K2317/56 , C07K2317/565 , C07K2317/73 , C07K2317/732 , C07K2317/734 , C07K2317/76
摘要: The present invention provides antibodies useful as therapeutics for treating and/or preventing diseases associated with cells expressing CLD18, including tumor-related diseases such as gastric cancer, esophageal cancer, pancreatic cancer, lung cancer, ovarian cancer, colon cancer, hepatic cancer, head-neck cancer, and cancer of the gallbladder.
摘要翻译: 本发明提供了可用作治疗和/或预防与表达CLD18的细胞相关的疾病的治疗剂的抗体,包括肿瘤相关疾病如胃癌,食管癌,胰腺癌,肺癌,卵巢癌,结肠癌,肝癌,头部 - 癌症和胆囊癌。
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13.
公开(公告)号:EP1790664A1
公开(公告)日:2007-05-30
申请号:EP05025657.7
申请日:2005-11-24
申请人: Ganymed Pharmaceuticals AG , Johannes Gutenberg-Universität Mainz, vertreten durch den Präsidenten
发明人: Sahin, Ugur , Türeci, Özlem , Fritz, Stefan , Uherek, Christoph , Brandenburg, Gunda , Geppert, Harald-Gerhard
IPC分类号: C07K16/30 , A61K39/395 , A61P35/00 , C12N5/12 , A61K47/48
CPC分类号: C07K16/18 , A61K39/3955 , A61K45/06 , A61K47/6803 , A61K47/6807 , A61K47/6809 , A61K47/6813 , A61K47/6821 , A61K47/6823 , A61K47/6829 , A61K47/6851 , A61K47/6859 , A61K47/6863 , A61K47/6869 , A61K51/1063 , A61K2039/505 , C07K16/28 , C07K16/3046 , C07K2317/14 , C07K2317/24 , C07K2317/51 , C07K2317/515 , C07K2317/56 , C07K2317/565 , C07K2317/73 , C07K2317/732 , C07K2317/734 , C07K2317/76
摘要: The present invention provides antibodies useful as therapeutics for treating and/or preventing diseases associated with cells expressing CLD18, including tumor-related diseases such as gastric cancer, esophageal cancer, pancreatic cancer, lung cancer, ovarian cancer, colon cancer, hepatic cancer, head-neck cancer, and cancer of the gallbladder.
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公开(公告)号:EP2371848B8
公开(公告)日:2018-06-06
申请号:EP11002013.8
申请日:2005-05-18
IPC分类号: C07K14/47 , C07K16/30 , A61K39/395 , A61P35/00
CPC分类号: A61K6/00 , A61K47/6851 , A61K49/00 , A61K2039/505 , C07K14/47 , C07K14/705 , C07K16/18 , C07K16/28 , C07K16/30 , C07K16/303 , C07K16/3046 , C07K16/3076 , C07K16/44 , C07K2317/24 , C07K2317/34 , C07K2317/73 , C07K2317/75 , C12N9/88 , C12Y406/01002 , G01N33/57496
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公开(公告)号:EP2392593B1
公开(公告)日:2018-08-01
申请号:EP11002015.3
申请日:2005-05-18
IPC分类号: C07K14/47 , C07K16/30 , A61K39/395 , A61P35/00
CPC分类号: A61K6/00 , A61K47/6851 , A61K49/00 , A61K2039/505 , C07K14/47 , C07K14/705 , C07K16/18 , C07K16/28 , C07K16/30 , C07K16/303 , C07K16/3046 , C07K16/3076 , C07K16/44 , C07K2317/24 , C07K2317/34 , C07K2317/73 , C07K2317/75 , C12N9/88 , C12Y406/01002 , G01N33/57496
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