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    METHOD AND APPARATUS TO CONTROL DELIVERY OF HIGH-VOLTAGE AND ANTI-TACHY PACING THERAPY IN AN IMPLANTABLE MEDICAL DEVICE
    11.
    发明公开
    METHOD AND APPARATUS TO CONTROL DELIVERY OF HIGH-VOLTAGE AND ANTI-TACHY PACING THERAPY IN AN IMPLANTABLE MEDICAL DEVICE 有权
    一种用于控制高电压和antitachycardic起搏治疗应用程序在可植入医疗装置

    公开(公告)号：EP1418982A2

    公开(公告)日：2004-05-19

    申请号：EP02763358.5

    申请日：2002-07-25

    申请人： Medtronic, Inc.

    发明人： DEGROOT, Paul, J. ,  OUSDIGIAN, Kevin, T. ,  PADMANABHAN, Vasant ,  KRAUSE, Paul, G. ,  SHARMA, Vinod

    IPC分类号： A61N1/362

    CPC分类号： A61N1/3622 ,  A61N1/3688 ,  A61N1/3925 ,  A61N1/3956 ,  A61N1/3962 ,  A61N1/3987

    摘要： A system and method for delivering both anti-tachy pacing (ATP) therapy and high-voltage shock therapy in response to detection of abnormal cardiac rhythms is disclosed. The system controls the time between delivering ATP therapy and the charging of high-voltage capacitors in preparation for shock delivery based on a predetermined set of criteria. In one embodiment, the inventive system operates in an ATP during Capacitor Charging (ATP-DCC) mode wherein all, or substantially all, of the ATP therapy is delivered during charging of the high-voltage capacitors. Based on evaluation of the predetermined set of criteria, the system may switch to an additional ATP before Capacitor Charging (ATP-BCC) mode, wherein substantially all of the ATP therapy is delivered prior to charging of the high-voltage capacitor. According to one aspect of the invention, the predetermined set of criteria is based, at least in part, on the effectiveness of previously-delivered ATP therapy.

    METHOD AND APPARATUS FOR ACCURATELY DETERMINING HEART RATE VARIABILITY AND SYMPATHETIC RESERVE
    19.
    发明公开
    METHOD AND APPARATUS FOR ACCURATELY DETERMINING HEART RATE VARIABILITY AND SYMPATHETIC RESERVE 审中-公开
    方法和设备心率变异和交感神经储量的准确测定

    公开(公告)号：EP3071099A1

    公开(公告)日：2016-09-28

    申请号：EP14808797.6

    申请日：2014-11-21

    申请人： Medtronic, Inc.

    发明人： SHARMA, Vinod

    IPC分类号： A61B5/024 ,  A61B5/11

    CPC分类号： A61B5/0205 ,  A61B5/02405 ,  A61B5/04012 ,  A61B5/0408 ,  A61B5/0432 ,  A61B5/0464 ,  A61B5/1118 ,  A61B5/686

    摘要： An implantable monitoring device is disclosed for monitoring a patient's heart rate variability over time. The device includes a cardiac electrogram amplifier, a sensing electrode coupled to an input of the amplifier, timing circuitry, processing circuitry and a memory. The timing circuitry defines successive shorter time periods during each monitoring period. The processing circuitry relies upon electrogram activity that occurs during rest periods that extend as long as T1, all of which is stored into memory. Active periods are not considered as part of the heart rate variability calculation. The processing circuitry calculates median intervals between depolarizations of the patient's heart sensed by the amplifier during the shorter time periods and calculates a standard deviation of the median intervals during T2, a longer monitoring period.