专利检索 ap:("Memorial Sloan Kettering Cancer Center" OR "Eureka Therapeutics, Inc.") AND inv:"XU, Yiyang" 第 2 页

11.

发明公开
CONSTRUCTS SPECIFICALLY RECOGNIZING GLYPICAN 3 AND USES THEREOF 审中-公开

公开(公告)号：EP3615574A1

公开(公告)日：2020-03-04

申请号：EP18791195.3

申请日：2018-04-24

申请人： Eureka Therapeutics, Inc.

发明人： ZHANG, Pengbo , XU, Yiyang , MORALES, Javier , NAKANO, Yoko , LIU, Hong , XIANG, Jingyi , ACKER, Timothy

IPC分类号： C07K16/30 , C07K16/46 , C07K19/00 , G01N33/574 , A61K39/395 , A61P35/00

12.

发明公开
CONSTRUCTS TARGETING HISTONE H3 PEPTIDE/MHC COMPLEXES AND USES THEREOF 审中-公开

公开(公告)号：EP3568468A1

公开(公告)日：2019-11-20

申请号：EP18739104.0

申请日：2018-01-11

申请人： Eureka Therapeutics, Inc.

发明人： CHAN, Vivien, Wai-Fan , LIU, Hong , NAKANO, Yoko , XU, Yiyang

IPC分类号： C12N5/0783 , C12N15/85 , C07K16/28 , C07K16/30 , A61K39/395 , G01N33/574

13.

发明公开
CONSTRUCTS TARGETING NY-ESO-1 PEPTIDE/MHC COMPLEXES AND USES THEREOF 审中-公开
标题翻译：靶向NY-ESO-1肽/ MHC复合物的构建体及其用途

公开(公告)号：EP3313873A2

公开(公告)日：2018-05-02

申请号：EP16815452.4

申请日：2016-06-24

申请人： Eureka Therapeutics, Inc.

发明人： LIU, Cheng , LIU, Hong , XU, Yiyang , XIANG, Jingyi

IPC分类号： C07K14/705 , A61K39/395 , G01N33/574

CPC分类号： G01N33/57492 , C07K14/00 , C07K14/4748 , C07K16/2809 , C07K16/2833 , C07K16/3069 , C07K2317/21 , C07K2317/31 , C07K2317/32 , C07K2317/33 , C07K2317/34 , C07K2317/56 , C07K2317/622 , C07K2317/73 , C07K2317/92 , C07K2319/03 , G01N2333/70539

摘要： The present application provides constructs comprising an antibody moiety that specifically binds to a complex comprising an NY-ESO-1 peptide and an MHC class I protein. Also provided are methods of making and using these constructs.

14.

发明公开
ANTI-ROR1 ANTIBODIES 审中-公开
标题翻译：抗ROR1抗体

公开(公告)号：EP3297671A2

公开(公告)日：2018-03-28

申请号：EP16797161.3

申请日：2016-05-17

申请人： Five Prime Therapeutics, Inc. , Eureka Therapeutics, Inc.

发明人： WONG, Brian , MASTELLER, Emma , LIU, Cheng , XU, Yiyang , LIU, Hong , YAN, Su , XIANG, Jingyi , WANG, Pei

IPC分类号： A61K39/395 , C07K16/28 , C12N1/15 , C12N1/21 , G01N33/574

CPC分类号： C07K16/2803 , A61K38/05 , A61K47/6817 , A61K47/6851 , A61K47/6881 , A61K51/1027 , A61K51/1042 , A61K51/1096 , A61K2039/505 , A61P35/00 , A61P35/02 , C07K16/005 , C07K16/2809 , C07K16/30 , C07K2317/14 , C07K2317/21 , C07K2317/31 , C07K2317/34 , C07K2317/52 , C07K2317/55 , C07K2317/56 , C07K2317/565 , C07K2317/622 , C07K2317/732 , C07K2317/734 , C07K2317/76 , C07K2317/77 , C07K2317/92 , C07K2319/00 , G01N33/57492 , G01N2333/912

摘要： The invention relates to antibodies, and in particular, to antibodies exhibiting specificity for Receptor tyrosine kinase-like Orphan Receptors (ROR), and to uses thereof, for example in the treatment of cancer. The invention extends to polynucleotide and polypeptide sequences encoding the antibodies, and therapeutic uses thereof, and to diagnostic kits comprising these molecules. The invention also extends to antibody-drug conjugates and to uses thereof in therapy.

15.

发明公开
CONSTRUCTS TARGETING AFP PEPTIDE/MHC COMPLEXES AND USES THEREOF 审中-公开
标题翻译：靶向AFP肽/ MHC复合物的构建体及其用途

公开(公告)号：EP3277314A1

公开(公告)日：2018-02-07

申请号：EP16774381.4

申请日：2016-04-01

申请人： Eureka Therapeutics, Inc.

发明人： LIU, Cheng , LIU, Hong , XU, Yiyang , XIANG, Jingyi , LONG, Li

IPC分类号： A61K39/00 , A61K39/395

CPC分类号： C07K16/2809 , A61K38/00 , A61K39/00 , A61K39/395 , A61K2039/54 , C07K14/7051 , C07K14/70596 , C07K16/18 , C07K16/2833 , C07K16/303 , C07K2317/21 , C07K2317/31 , C07K2317/33 , C07K2317/34 , C07K2317/565 , C07K2317/622 , C07K2317/734 , C07K2317/92 , C07K2319/00 , C07K2319/02 , C07K2319/03

摘要： The present application provides constructs comprising an antibody moiety that specifically binds to a complex comprising an AFP peptide and an MHC class I protein. Also provided are methods of making and using these constructs.