公开(公告)号：EP2369346A2

公开(公告)日：2011-09-28

申请号：EP10196643.0

申请日：2007-03-21

申请人： Metanomics GmbH

发明人： Bethan, Bianca ,  Busch, Kristina ,  Wiemer, Jan ,  Gipmans, Martijn ,  Leibold, Edgar ,  Spranger, Jochen ,  Bobbert, Thomas ,  Pfeiffer, Andreas Friedrich Hermann

IPC分类号： G01N33/62 ,  G01N33/66 ,  G01N33/68 ,  G01N33/70 ,  G01N33/92 ,  G01N33/82

CPC分类号： G01N33/92 ,  G01N33/6848 ,  G01N33/6893 ,  G01N2800/042 ,  G01N2800/52 ,  Y10T436/144444 ,  Y10T436/24

摘要： The present invention relates to a method for diagnosing diabetes or a predisposition thereof comprising determining at least one metabolite in a test sample of a subject suspected to suffer from diabetes or to have a predisposition therefor and comparing said at least one metabolite to a reference, whereby diabetes or a predisposition therefor is to be diagnosed. Moreover, the present invention encompasses a collection of metabolites, a data collection comprising characteristic values of metabolites and a storage medium comprising said data collection. Furthermore, the present invention also relates to a system comprising means for comparing characteristic values of metabolites of a sample operatively linked to a data storage medium. Further encompassed by the present invention are diagnostic means comprising at least one metabolite and the use of said at least one metabolite for the manufacture of diagnostic means for diagnosing diabetes. Finally, the present invention pertains to a method for identifying diabetes-related metabolites.

摘要翻译： 本发明涉及一种用于诊断糖尿病或其易感性的方法，包括测定疑似患有糖尿病的受试者的测试样品中的至少一种代谢物或具有易感性并将所述至少一种代谢物与参考对比，由此 要诊断糖尿病或倾向。 此外，本发明包括代谢物的集合，包括代谢物的特征值的数据收集和包含所述数据收集的存储介质。 此外，本发明还涉及一种系统，其包括用于比较可操作地连接到数据存储介质的样品的代谢物的特征值的装置。 本发明进一步包括的是包含至少一种代谢物和所述至少一种代谢物用于制造用于诊断糖尿病的诊断装置的诊断方法。 最后，本发明涉及鉴定糖尿病相关代谢物的方法。