公开(公告)号：EP1966165A1

公开(公告)日：2008-09-10

申请号：EP06841065.3

申请日：2006-12-20

申请人： Novartis AG

发明人： COLLINGWOOD, Stephen, Paul ,  SMITH, Nichola ,  LEGRAND, Darren, Mark

IPC分类号： C07D241/32 ,  C07D403/12 ,  C07D451/04 ,  A61K31/497 ,  A61K31/4965 ,  A61P11/00 ,  A61P29/00 ,  A61P37/00

CPC分类号： C07D241/26 ,  C07D403/12 ,  C07D451/04

摘要： A compound of formula (I) or tautomers, or stereoisomers, or solvates, or pharmaceutically acceptable salts thereof, wherein R1, R2, R3, R4, R5, T, L, W, X, Y and A are as defined herein for the for treatment of conditions mediated by the blockade of an epithelial sodium channel, particularly an inflammatory or allergic condition.

公开(公告)号：EP1957072A1

公开(公告)日：2008-08-20

申请号：EP06818673.3

申请日：2006-11-20

申请人： Novartis AG

发明人： COLLINGWOOD, Stephen, Paul ,  HAEBERLIN, Barbara

IPC分类号： A61K31/4704 ,  A61K31/40 ,  A61K31/58 ,  A61P11/00 ,  A61P43/00

CPC分类号： A61K31/40 ,  A61K31/4704 ,  A61K31/58 ,  A61K2300/00

摘要： A medicament comprising, separately or together (A) a compound of formula (I) in free or salt or solvate form, wherein W, Rx, Ry, R1, R2, R3, R4, R5, R6 and R7 have the meanings as indicated in the specification; (B) a glycopyrronium salt; and (C) mometasone furoate; for simultaneous, sequential or separate administration in the treatment of an inflammatory or obstructive airways disease.

公开(公告)号：EP1954266A1

公开(公告)日：2008-08-13

申请号：EP06818679.0

申请日：2006-11-20

申请人： Novartis AG

发明人： COLLINGWOOD, Stephen, Paul ,  HAEBERLIN, Barbara

IPC分类号： A61K31/40 ,  A61K31/58 ,  A61K9/00 ,  A61P11/06 ,  A61P11/08

CPC分类号： A61K9/0075 ,  A61K9/008 ,  A61K31/40 ,  A61K31/58 ,  A61K2300/00

摘要： Medicaments comprising (A) an antimuscarinic agent and (B) a corticosteroid for the treatment of inflammatory or obstructive airways diseases.

摘要翻译： 包含（A）抗毒蕈碱剂和（B）皮质类固醇的药物，用于治疗炎性或阻塞性气道疾病。