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17 条记录 (耗时 0.013 秒)

    Thiazolidine derivatives
    11.
    发明公开
    Thiazolidine derivatives 失效
    噻唑烷衍。

    公开(公告)号：EP0067569A1

    公开(公告)日：1982-12-22

    申请号：EP82302682.8

    申请日：1982-05-25

    申请人： TAISHO PHARMACEUTICAL CO. LTD

    发明人： Takano, Seiichi ,  Otomo, Susumu ,  Amano, Takehiro

    IPC分类号： C07D277/06 ,  C07D417/06 ,  A61K31/425

    CPC分类号： C07D277/06

    摘要： A novel thiazolidine derivative having the following general formula
    wherein R 1 and R 2 are each lower alkyl having 1 to 3 carbon atoms, or R' and R 2 together with the nitrogen atom to which they are attached form morpholino, piperazino, piperidino or pyrrolidino, or each one of which is substituted with 1 or 2 methyl groups and the pharmaceutically acceptable salts thereof, is a useful immunomodulator.

    Azaanthracene compounds
    14.
    发明公开
    Azaanthracene compounds 失效
    氮杂蒽化合物

    公开(公告)号：EP0234931A1

    公开(公告)日：1987-09-02

    申请号：EP87301637.2

    申请日：1987-02-25

    申请人： TAISHO PHARMACEUTICAL CO. LTD

    发明人： Nakagami, Jozi ,  Eguchi, Tadashi ,  Amano, Takehiro ,  Sota, Kaoru ,  Sakakibara, Jinsaku

    IPC分类号： C07D471/04 ,  C07D475/12 ,  C07D487/04

    CPC分类号： C07D471/04 ,  C07D475/12

    摘要： Azaanthracene compounds of the general formula
    (wherein one or two of X, Y and Z are nitrogen atoms, the others are CH, R¹ and R² are the same or different and are hydrogen atoms, lower alkyl groups or β-hydroxyethyl groups, and n is 2 or 3) and the acid addition salts thereof have antitumor activity. They can be prepared by reaction of the corresponding 6-ethoxycarbonyl compound with a dialkyl-, or di-­(hydroxyalkyl)-aminoalkylamine.

    摘要翻译： 通式的氮杂蒽化合物（其中X，Y和Z中的一个或两个为氮原子，其余为CH，R 1和R 2相同或不同且为氢原子，低级烷基或β-羟乙基，n 是2或3）并且其酸加成盐具有抗肿瘤活性。 它们可以通过相应的6-乙氧基羰基化合物与二烷基 - 或二 - （羟烷基） - 氨基烷基胺的反应来制备。