公开(公告)号：EP0068171A1

公开(公告)日：1983-01-05

申请号：EP82104885.7

申请日：1982-06-03

申请人： Yoshitomi Pharmaceutical Industries, Ltd.

发明人： Araki, Kazuhiko ,  Ao, Hideki ,  Kimura, Tomohiko ,  Aihara, Kenichi

IPC分类号： C07D401/12 ,  C07D407/12 ,  C07D409/12 ,  A61K31/445

CPC分类号： C07D401/12 ,  C07D307/52 ,  C07D333/20 ,  C07D405/12 ,  C07D409/12 ,  C07D413/12 ,  C07D417/12

摘要： A dihydropyridine compound of the formula:
or a pharmaceutically acceptable acid addition salt thereof, wherein Het is 5- or 6-membered aromatic heteroaryl, R' and R 2 are each lower alkyl, R 3 is lower alkyl, R 4 is hydrogen, lower alkyl or aralkyl, R 5 is lower alkyl or aralkyl, and n is 1 or 2. Such compounds are useful as therapeutic agents for myocardial and cerebral ischemic syndroms and hypertension.