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公开(公告)号：EP0068171B1
公开(公告)日：1985-10-09
申请号：EP82104885.7
申请日：1982-06-03
发明人： Araki, Kazuhiko , Ao, Hideki , Kimura, Tomohiko , Aihara, Kenichi
IPC分类号： C07D401/12 , C07D407/12 , C07D409/12 , A61K31/445
CPC分类号： C07D401/12 , C07D307/52 , C07D333/20 , C07D405/12 , C07D409/12 , C07D413/12 , C07D417/12
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公开(公告)号：EP0068171A1
公开(公告)日：1983-01-05
申请号：EP82104885.7
申请日：1982-06-03
发明人： Araki, Kazuhiko , Ao, Hideki , Kimura, Tomohiko , Aihara, Kenichi
IPC分类号： C07D401/12 , C07D407/12 , C07D409/12 , A61K31/445
CPC分类号： C07D401/12 , C07D307/52 , C07D333/20 , C07D405/12 , C07D409/12 , C07D413/12 , C07D417/12
摘要： A dihydropyridine compound of the formula:
or a pharmaceutically acceptable acid addition salt thereof, wherein Het is 5- or 6-membered aromatic heteroaryl, R' and R 2 are each lower alkyl, R 3 is lower alkyl, R 4 is hydrogen, lower alkyl or aralkyl, R 5 is lower alkyl or aralkyl, and n is 1 or 2. Such compounds are useful as therapeutic agents for myocardial and cerebral ischemic syndroms and hypertension.
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