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21.发明授权
公开(公告)号：EP3469636B1
公开(公告)日：2024-02-07
申请号：EP17809503.0
申请日：2017-06-08
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公开(公告)号：EP3871014B1
公开(公告)日：2023-11-29
申请号：EP19882323.9
申请日：2019-10-29
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公开(公告)号：EP2608897B1
公开(公告)日：2023-08-02
申请号：EP11819487.7
申请日：2011-08-29
IPC分类号： B06B3/00 , G10K15/02 , G10K15/04 , A61B17/225
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公开(公告)号：EP3710399A1
公开(公告)日：2020-09-23
申请号：EP18879788.0
申请日：2018-11-16
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公开(公告)号：EP3590281A1
公开(公告)日：2020-01-08
申请号：EP18761817.8
申请日：2018-03-05
发明人： POULIN, David , FERRIS, Andrew J.
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26.发明公开ATP SYNTHASE INHIBITORS AND STEROID ALKALOIDS AND USES THEREOF AS ANTIMICROBIAL AGENTS AND AS POTENTIATORS FOR AMINOGLYCOSIDES AGAINST PATHOGENIC BACTERIA 审中-公开ATP合成酶抑制剂和类固醇生物碱及其用途抗菌剂和增效剂对致病菌氨基糖苷类药物
公开(公告)号：EP3087082A1
公开(公告)日：2016-11-02
申请号：EP14873837.0
申请日：2014-12-23
CPC分类号： A61K31/58 , A61K31/57 , A61K31/7036 , A61K45/06 , C07J41/005 , C07J71/0005 , C12N9/14 , A61K2300/00
摘要： The present invention provides bacterial ATP synthase inhibitors such as a compound of formula (I): (Formula (I)) (A) in combination with an aminoglycoside antibiotic for preventing or treating a bacterial infection in a subject; or (B) (a) for preventing or treating an infection caused by an electron transport-deficient bacteria in a subject; or (b) for the disinfection, sterilization and/or antisepsis of an object contaminated with an electron transport-deficient bacteria. There are provided compositions and kits using such compounds and inhibitors.
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27.发明授权ENDOGENOUS AUTO-FLUORESCENT BIOLOGICAL MARKERS FOR ASSESSING A BIOLOGICAL PARAMETER OF A CELL 有权内源性有机自发荧光标记物测量细胞的生物学参数
公开(公告)号：EP2347005B1
公开(公告)日：2015-09-23
申请号：EP09820169.2
申请日：2009-10-16
CPC分类号： G01N21/6428 , C12Q1/02 , C12Q1/06 , G01N21/6408 , G01N21/6458 , G01N21/6486 , G01N33/487 , G01N33/582 , G01N2021/6491
摘要： The present application relates to the use of endogenous fluorescent biological markers to determine a biological parameter of a cell in a liquid. The methods provided herein provide accurate results in a relatively short amount of time and can be used to monitor and optimize cell culture online as well as determining the presence of a cellular contamination in a cell suspension.
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28.发明公开COMBUSTION SYSTEMS AND COMBUSTION SYSTEM COMPONENTS FOR ROTARY RAMJET ENGINES 审中-公开燃烧系统和燃烧系统部件的转子发动机冲压发动机引擎
公开(公告)号：EP2721273A1
公开(公告)日：2014-04-23
申请号：EP12800390.2
申请日：2012-05-25
CPC分类号： F23R3/28 , F02C3/165 , F02C7/264 , F02K7/10 , F23R3/18 , F23R3/286 , F23R3/343 , F23R2900/00012 , F23R2900/03343 , Y02T50/672
摘要： The present disclosure relates to combustion systems and components for rotary ramjet engines. An injection system, optionally stratified for ease of engine startup, provides an air and fuel mixture to a combustion chamber. An ignition system ignites the mixture. A flameholding system may be positioned for communication with the combustion chamber to force an ignited flow of the air and fuel mixture toward a center of rotation within the ramjet engine. The ramjet engine may comprise a diverging stator for improved exhaust efficiency. Ignition may take place in the engine air intake. Alternatively, ignition may take place within the combustion chamber using a dual-hub electrically charged system. An impulse turbine may use recirculation of injected fuel to cool a rim-rotor and/or to reduce windage on the rim-rotor. A sealing system may reduce gas leaks from a fuel conduit into the engine air intake.
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29.发明公开STEROID ALKALOIDS AND USES THEREOF AS ANTIMICROBIAL AGENTS AGAINST ELECTRON TRANSPORT-DEFICIENT MICROBES AND AS POTENTIATORS FOR ANTIMICROBIAL AGENTS AGAINST PATHOGENIC BACTERIA 审中-公开STEROIDALKALOIDDERIVATE及其作为抗菌药物对具有电子传输芽和缺乏作为增效剂用于抗微生物活性物质致病细菌上
公开(公告)号：EP2675822A1
公开(公告)日：2013-12-25
申请号：EP12747258.7
申请日：2012-02-15
发明人： MALOUIN, François , MITCHELL, Gabriel , BOUARAB, Kamal , MARSAULT, Eric , CHAGNON, Félix , BOULANGER, Simon , GUAY, Isabelle
CPC分类号： A61K31/58 , A01N45/00 , A61K31/395 , A61K31/7036 , A61L2/16 , C07J7/002 , C07J7/006 , C07J7/007 , C07J7/0085 , C07J41/005 , C07J41/0055 , C07J43/003 , C07J43/006 , C07J51/00 , G01N2800/52 , A61K2300/00
摘要： The present invention includes novel compounds based on the tomatidine skeleton as well as composition comprising these compounds alone and in combination with known compounds, which exhibit antimicrobial activity against extracellular or intracellular electron transport-deficient microbes and/or increase the antimicrobial activity of aminoglycoside antibiotics against their targets, and which are useful as antibacterial agents for treatment or prophylaxis of monomicrobiotic or polymicrobic bacterial infections or for the reduction of antibiotic resistance development in animals or in humans, or for use as antiseptics or agents for sterilization or disinfection.
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30.发明公开BACTERIAL VACCINE COMPONENTS FROM STAPHYLOCOCCUS AUREUS AND USES THEREOF 审中-公开大肠杆菌感染大肠杆菌Aureus UND VERWENDUNGEN DAVON
公开(公告)号：EP2547361A1
公开(公告)日：2013-01-23
申请号：EP11755607.6
申请日：2011-03-17
发明人： MALOUIN, François , ALLARD, Marianne , LEBEAU JACOB, Christian , TALBOT, Brian Geoffrey , SCHOLL, Daniel , LACASSE, Pierre , DIARRA, Moussa S. , STER, Céline
摘要： Agents, compositions, methods and kits useful for the treatment and diagnosis of Staphylococcal intramammary infection are disclosed. The agents, compositions, methods and kits are derived from genes expressed during Staphylococcal intramammary infection, and more particularly genes SACOL0029, based on the gene nomenclature from the Staphylococcus aureus COL (SACOL) genome.
摘要翻译： 公开了用于治疗和诊断葡萄球菌乳腺内感染的药剂，组合物，方法和试剂盒。 代谢物，组合物，方法和试剂盒衍生自在葡萄球菌乳腺内感染期间表达的基因，更具体地是基于该基因的基因SACOL0029，SACOL0264，SACOL0442，SACOL0718，SACOL0720，SACOL1353，SACOL1416，SACOL1611，SACOL1944，SACOL2144，SACOL2365或SACOL2599 来自金黄色葡萄球菌COL（SACOL）基因组的命名法。
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