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公开(公告)号:EP4134430A1
公开(公告)日:2023-02-15
申请号:EP22180254.9
申请日:2016-02-05
发明人: CAMPANA, Dario , KAMIYA, Takahiro
IPC分类号: C12N5/0783 , C12N5/10 , A61K35/17 , C07K16/28 , C12N15/13
摘要: The present invention relates to a method of using a receptor (e.g., chimeric antigen receptor - CAR) that activates an immune response upon binding a cancer cell ligand in conjunction with a target-binding molecule that targets a protein or molecule for removal or neutralization to generate enhanced anti-cancer immune cells. The present invention also relates to engineered immune cells having enhanced therapeutic efficacy and uses thereof.
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公开(公告)号:EP4121539A1
公开(公告)日:2023-01-25
申请号:EP21772330.3
申请日:2021-03-22
IPC分类号: C12N15/113 , C12N15/63 , A61K38/43 , A61P31/14
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23.
公开(公告)号:EP4061968A2
公开(公告)日:2022-09-28
申请号:EP20889994.8
申请日:2020-11-20
IPC分类号: C12Q1/6886 , A61K38/08 , G01N33/574 , A61K39/395 , A61K35/17 , A61P35/00
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公开(公告)号:EP4041875A1
公开(公告)日:2022-08-17
申请号:EP20874305.4
申请日:2020-10-12
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公开(公告)号:EP3999641A2
公开(公告)日:2022-05-25
申请号:EP20840604.1
申请日:2020-07-15
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公开(公告)号:EP3999082A1
公开(公告)日:2022-05-25
申请号:EP20841097.7
申请日:2020-07-15
发明人: SHIMASAKI, Noriko , CAMPANA, Dario
IPC分类号: A61K35/17 , C12N15/13 , A61K39/395 , A61K38/19 , A61P35/00
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公开(公告)号:EP3990621A1
公开(公告)日:2022-05-04
申请号:EP20831995.4
申请日:2020-06-26
发明人: RACKHAM, Owen , PETRETTO, Enrico , KAMARAJ, Uma , POLO, Jose , CHEN, Joseph
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公开(公告)号:EP3989814A1
公开(公告)日:2022-05-04
申请号:EP20832397.2
申请日:2020-06-25
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公开(公告)号:EP3987292A1
公开(公告)日:2022-04-27
申请号:EP20826392.1
申请日:2020-06-19
IPC分类号: G01N33/574 , C12Q1/6886
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公开(公告)号:EP3968909A1
公开(公告)日:2022-03-23
申请号:EP20806038.4
申请日:2020-05-15
IPC分类号: A61F5/01 , B25J9/00 , B25J13/08 , A61H9/00 , A61B17/135
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