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    TREATMENT OF SCAR TISSUE USING LIPOIC ACID
    21.
    发明公开
    TREATMENT OF SCAR TISSUE USING LIPOIC ACID 有权
    治疗硫辛酸的瘢痕组织

    公开(公告)号：EP1039891A1

    公开(公告)日：2000-10-04

    申请号：EP98958031.1

    申请日：1998-11-16

    申请人： PERRICONE, Nicholas V., Dr.

    发明人： PERRICONE, Nicholas V., Dr.

    IPC分类号： A61K31/19

    CPC分类号： A61Q19/00 ,  A61K8/365 ,  A61K8/4986 ,  A61K31/385 ,  A61K45/06 ,  A61K31/335 ,  A61K31/19 ,  A61K2300/00

    摘要： Scar tissue is reduced or inhibited by application of a composition containing lipoic acid and/or a lipoic acid derivative such as dihydrolipoic acid, a lipoic or dihydrolipoic acid ester, a lipoic or dihydrolipoic acid amide, a lipoic or dihydrolipoic acid salt, and mixtures of any of these. Some compositions further comprise α-hydroxy acids or acid derivatives such as glycolic and/or lactic acid, fatty acid esters of ascorbic acid such as ascorbyl palmitate, and/or tocotrienol. In some embodiments, a silicone gel sheet with added lipoic acid and/or a lipoic acid derivative and optional other ingredients is topically applied to scar tissue to diminish them.

    Compositions for topical application to the skin for treatment and/or prevention of radiation-induced skin damage
    23.
    发明公开
    Compositions for topical application to the skin for treatment and/or prevention of radiation-induced skin damage 失效
    用于治疗和/或预防，由于通过局部施用到皮肤上的皮肤的辐射损伤。

    公开(公告)号：EP0607642A1

    公开(公告)日：1994-07-27

    申请号：EP93300324.6

    申请日：1993-01-19

    申请人： PERRICONE, Nicholas V., Dr.

    发明人： PERRICONE, Nicholas V., Dr.

    IPC分类号： A61K7/48 ,  A61K7/42 ,  A61K31/375

    CPC分类号： A61Q19/004 ,  A61K8/676 ,  A61K31/375

    摘要： A method and composition for the cosmetic and therapeutic treatment or prevention of radiation-induced skin damage, in which a fat-soluble fatty acid ester of ascorbic acid is topically applied to the affected or involved skin areas, preferably in association with a dermatologically acceptable carrier. The preferred esters are the palmitate, laurate, myristate and stearate.

    摘要翻译： 一种用于辐射诱导的皮肤损伤的化妆品和治疗性治疗或预防，其中的抗坏血酸的脂溶性脂肪酸酯局部施用于受影响的或涉及的皮肤区域，优选地在关联与皮肤病学上可接受的载体的方法和组合物 ， 的优选的酯是棕榈酸酯，月桂酸酯，肉豆蔻酸和硬脂酸。

    HAIR AND NAIL TREATMENTS USING ALKANOLAMINES
    25.
    发明公开
    HAIR AND NAIL TREATMENTS USING ALKANOLAMINES 审中-公开
    HAAR- UND NAGELBEHANDLUNGEN MIT ALKANOLAMINEN

    公开(公告)号：EP1515715A4

    公开(公告)日：2006-06-14

    申请号：EP03762018

    申请日：2003-06-26

    申请人： PERRICONE NICHOLAS V DR

    发明人： PERRICONE NICHOLAS V

    IPC分类号： A61K8/00 ,  A61K8/30 ,  A61K8/36 ,  A61K8/365 ,  A61K8/41 ,  A61K8/44 ,  A61K8/49 ,  A61K8/67 ,  A61P17/00 ,  A61P17/10 ,  A61Q3/00 ,  A61Q3/02 ,  A61Q5/00 ,  A61Q19/00 ,  A61K31/385 ,  A61K31/13 ,  A61K31/195 ,  A61K31/20

    CPC分类号： A61Q7/00 ,  A61K8/41 ,  A61Q3/00 ,  A61Q19/00

    摘要： Topical application of compositions containing an alkanolamine such as dimethylaminoethanol increase smoothness and surface uniformity of hair and nails and enhances hair and nail growth. Application to the hair and underlying skin areas containing the hair bulbs, fingernails or toenails and paraungual areas containing the nail matrices increases the elasticity and enhances the luster of hair and nails, provides emolliency to their keratin matrix, and quells inflammation to promote superior keratin formation. Alkanolamine compositions contain at least one other adjunct ingredient such as tyrosine, lipoic acid, folic acid, an oz-hydroxy acid, or a fatty acid ester of ascorbic acid in most embodiments to augment beneficial effects of the treatments.

    摘要翻译： 包含链烷醇胺如二甲基氨基乙醇的组合物的局部应用增加头发和指甲的光滑度和表面均匀性，并增强头发和指甲的生长。 适用于包含头发，指甲或脚趾甲的头发和底层皮肤区域，以及包含指甲基质的边缘区域增加了弹性并增强了头发和指甲的光泽，为其角蛋白基质提供了润肤性，并且镇静炎症以促进优异的角蛋白形成 。 在大多数实施方案中，链烷醇胺组合物含有至少一种其它辅助成分，例如酪氨酸，硫辛酸，叶酸，α-羟基酸或抗坏血酸的脂肪酸酯，以增强治疗的有益效果。

    TREATMENT OF SKIN DAMAGE USING POLYENYLPHOSPHATIDYLCHOLINE
    26.
    发明公开
    TREATMENT OF SKIN DAMAGE USING POLYENYLPHOSPHATIDYLCHOLINE 审中-公开
    治疗多烯磷脂对皮肤的伤害

    公开(公告)号：EP1267798A1

    公开(公告)日：2003-01-02

    申请号：EP00946854.7

    申请日：2000-06-23

    申请人： PERRICONE, Nicholas V., Dr.

    发明人： PERRICONE, Nicholas V., Dr.

    IPC分类号： A61K7/00 ,  A61K31/685

    CPC分类号： A61Q19/007 ,  A61K8/553 ,  A61K31/685 ,  A61Q19/00 ,  A61Q19/08

    摘要： Polyenylphosphatidylcholine is topically applied to treat skin damage, such as contact dermatitis (particularly diaper area dermatitis), atopic dermatitis, xerosis, eczema (including severe hand and foot eczema), rosacea, seborrhea, psoriasis, thermal and radiation burns, other types of skin inflammation, and aging. Typical compositions contain from about 0.25 % to about 10 % of a polyenylphosphatidylcholine preparation obtained form natural sources such as soybean oil which contains at least about 25 % by weight, preferably about 40 % or more, dilinoeoylphosphatidylcholine.