专利检索 ap:("Chia Tai Tianqing Pharmaceutical Group Co., Ltd." OR "Lianyungang Runzhong Pharmaceutical Co., Ltd." OR "Centaurus BioPharma Co., Ltd.") AND inv:"ZHAO, Rui" 第 3 页

21.

发明公开
TLR7 AGONIST TRIFLUOROACETATE SALT AND CRYSTALLINE FORM B THEREOF, PREPARATION METHODS AND USES 审中-公开

公开(公告)号：EP3412674A1

公开(公告)日：2018-12-12

申请号：EP17747007.7

申请日：2017-02-04

申请人： Chia Tai Tianqing Pharmaceutical Group Co.,Ltd

发明人： DING, Zhaozhong , SUN, Fei , HU, Yinghu , ZHOU, Yilong , WANG, Zheng , ZHAO, Rui , YANG, Ling

IPC分类号： C07D487/04 , A61K31/519 , A61P31/12

摘要： The present invention relates to a trifluoroacetate salt of a TLR7 agonist 2-butoxy-7-(4-(pyrrolidin-1-ylmethyl)benzyl)-5H-pyrrolo[3,2-d]pyrimidin-4-amine (formula I), crystalline form B of the trifluoroacetate salt, methods for preparing the trifluoroacetate salt and crystalline form B, and uses of the trifluoroacetate salt and crystalline form B.