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公开(公告)号：EP2433962A2
公开(公告)日：2012-03-28
申请号：EP11003891.6
申请日：2006-09-06
申请人： Ganymed Pharmaceuticals AG , Johannes Gutenberg-Universität Mainz, vertreten durch den Präsidenten
发明人： Sahin, Ugur , Türeci, Özlem , Koslowski, Michael , Usener, Dirk
CPC分类号： A61K39/0011 , A61K45/06 , A61K2039/5256 , A61K2039/54 , A61K2039/57 , A61K2039/572 , C07K14/4748 , C07K16/2803 , C07K16/30 , C07K2317/34 , C12Q1/6886 , C12Q2600/158 , G01N33/574
摘要： The invention relates to genetic products the expression of which is associated with cancer diseases. The invention also relates to the therapy and diagnosis of diseases in which the genetic products are expressed or aberrantly expressed, in particular cancer diseases.
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公开(公告)号：EP2433961A2
公开(公告)日：2012-03-28
申请号：EP11003890.8
申请日：2006-09-06
申请人： Ganymed Pharmaceuticals AG , Johannes Gutenberg-Universität Mainz, vertreten durch den Präsidenten
发明人： Sahin, Ugur , Türeci, Özlem , Koslowski, Michael , Usener, Dirk
CPC分类号： A61K39/0011 , A61K45/06 , A61K2039/5256 , A61K2039/54 , A61K2039/57 , A61K2039/572 , C07K14/4748 , C07K16/2803 , C07K16/30 , C07K2317/34 , C12Q1/6886 , C12Q2600/158 , G01N33/574
摘要： The invention relates to genetic products the expression of which is associated with cancer diseases. The invention also relates to the therapy and diagnosis of diseases in which the genetic products are expressed or aberrantly expressed, in particular cancer diseases.
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23.发明公开
公开(公告)号：EP2433956A2
公开(公告)日：2012-03-28
申请号：EP11003885.8
申请日：2006-09-06
申请人： Ganymed Pharmaceuticals AG , Johannes Gutenberg-Universität Mainz, vertreten durch den Präsidenten
发明人： Sahin, Ugur , Türeci, Özlem , Koslowski, Michael , Usener, Dirk
CPC分类号： A61K39/0011 , A61K45/06 , A61K2039/5256 , A61K2039/54 , A61K2039/57 , A61K2039/572 , C07K14/4748 , C07K16/2803 , C07K16/30 , C07K2317/34 , C12Q1/6886 , C12Q2600/158 , G01N33/574
摘要： The invention relates to genetic products the expression of which is associated with cancer diseases. The invention also relates to the therapy and diagnosis of diseases in which the genetic products are expressed or aberrantly expressed, in particular cancer diseases.
摘要翻译： 本发明涉及其表达与癌症疾病相关的遗传产物。 本发明还涉及遗传产物表达或异常表达，特别是癌症疾病的疾病的治疗和诊断。
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24.发明公开
公开(公告)号：EP2295469A3
公开(公告)日：2011-05-18
申请号：EP10011774.6
申请日：2006-11-24
申请人： Ganymed Pharmaceuticals AG , Johannes Gutenberg-Universität Mainz, vertreten durch den Präsidenten
发明人： Sahin, Ugur , Türeci, Özlem , Usener, Dirk , Fritz, Stefan , Uherek, Christoph , Brandenburg, Gunda , Geppert, Harald-Gerhard , Schröder, Anja Kristina , Thiel, Philippe
IPC分类号： C07K16/30 , A61K39/395 , A61P35/00 , C12N5/12 , A61K47/48
CPC分类号： C07K16/18 , A61K39/3955 , A61K45/06 , A61K47/6803 , A61K47/6807 , A61K47/6809 , A61K47/6813 , A61K47/6821 , A61K47/6823 , A61K47/6829 , A61K47/6851 , A61K47/6859 , A61K47/6863 , A61K47/6869 , A61K51/1063 , A61K2039/505 , C07K16/28 , C07K16/3046 , C07K2317/14 , C07K2317/24 , C07K2317/51 , C07K2317/515 , C07K2317/56 , C07K2317/565 , C07K2317/73 , C07K2317/732 , C07K2317/734 , C07K2317/76
摘要： The present invention provides antibodies useful as therapeutics for treating and/or preventing diseases associated with cells expressing CLD18, including tumor-related diseases such as gastric cancer, esophageal cancer, pancreatic cancer, lung cancer, ovarian cancer, colon cancer, hepatic cancer, head-neck cancer, and cancer of the gallbladder.
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公开(公告)号：EP2311878B1
公开(公告)日：2015-10-07
申请号：EP10011775.3
申请日：2006-11-24
申请人： Ganymed Pharmaceuticals AG , Johannes Gutenberg-Universität Mainz, vertreten durch den Präsidenten
发明人： Sahin, Ugur , Türeci, Özlem , Usener, Dirk , Fritz, Stefan , Uherek, Christoph , Brandenburg, Gunda , Geppert, Harald-Gerhard , Schröder, Anja Kristina , Thiel, Philippe
CPC分类号： C07K16/18 , A61K39/3955 , A61K45/06 , A61K47/6803 , A61K47/6807 , A61K47/6809 , A61K47/6813 , A61K47/6821 , A61K47/6823 , A61K47/6829 , A61K47/6851 , A61K47/6859 , A61K47/6863 , A61K47/6869 , A61K51/1063 , A61K2039/505 , C07K16/28 , C07K16/3046 , C07K2317/14 , C07K2317/24 , C07K2317/51 , C07K2317/515 , C07K2317/56 , C07K2317/565 , C07K2317/73 , C07K2317/732 , C07K2317/734 , C07K2317/76
摘要： The present invention provides antibodies useful as therapeutics for treating and/or preventing diseases associated with cells expressing CLD18, including tumor-related diseases such as gastric cancer, esophageal cancer, pancreatic cancer, lung cancer, ovarian cancer, colon cancer, hepatic cancer, head-neck cancer, and cancer of the gallbladder.
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公开(公告)号：EP2433955A3
公开(公告)日：2012-07-04
申请号：EP11003884.1
申请日：2006-09-06
申请人： Ganymed Pharmaceuticals AG , Johannes Gutenberg-Universität Mainz, vertreten durch den Präsidenten
发明人： Sahin, Ugur , Türeci, Özlem , Koslowski, Michael , Usener, Dirk
CPC分类号： A61K39/0011 , A61K45/06 , A61K2039/5256 , A61K2039/54 , A61K2039/57 , A61K2039/572 , C07K14/4748 , C07K16/2803 , C07K16/30 , C07K2317/34 , C12Q1/6886 , C12Q2600/158 , G01N33/574
摘要： The invention relates to genetic products the expression of which is associated with cancer diseases. The invention also relates to the therapy and diagnosis of diseases in which the genetic products are expressed or aberrantly expressed, in particular cancer diseases.
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27.发明公开
公开(公告)号：EP2433961A3
公开(公告)日：2012-06-27
申请号：EP11003890.8
申请日：2006-09-06
申请人： Ganymed Pharmaceuticals AG , Johannes Gutenberg-Universität Mainz, vertreten durch den Präsidenten
发明人： Sahin, Ugur , Türeci, Özlem , Koslowski, Michael , Usener, Dirk
CPC分类号： A61K39/0011 , A61K45/06 , A61K2039/5256 , A61K2039/54 , A61K2039/57 , A61K2039/572 , C07K14/4748 , C07K16/2803 , C07K16/30 , C07K2317/34 , C12Q1/6886 , C12Q2600/158 , G01N33/574
摘要： The invention relates to genetic products the expression of which is associated with cancer diseases. The invention also relates to the therapy and diagnosis of diseases in which the genetic products are expressed or aberrantly expressed, in particular cancer diseases.
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公开(公告)号：EP2433957A2
公开(公告)日：2012-03-28
申请号：EP11003886.6
申请日：2006-09-06
申请人： Ganymed Pharmaceuticals AG , Johannes Gutenberg-Universität Mainz, vertreten durch den Präsidenten
发明人： Sahin, Ugur , Türeci, Özlem , Koslowski, Michael , Usener, Dirk
CPC分类号： A61K39/0011 , A61K45/06 , A61K2039/5256 , A61K2039/54 , A61K2039/57 , A61K2039/572 , C07K14/4748 , C07K16/2803 , C07K16/30 , C07K2317/34 , C12Q1/6886 , C12Q2600/158 , G01N33/574
摘要： The invention relates to genetic products the expression of which is associated with cancer diseases. The invention also relates to the therapy and diagnosis of diseases in which the genetic products are expressed or aberrantly expressed, in particular cancer diseases.
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公开(公告)号：EP2433954A2
公开(公告)日：2012-03-28
申请号：EP11003883.3
申请日：2006-09-06
申请人： Ganymed Pharmaceuticals AG , Johannes Gutenberg-Universität Mainz, vertreten durch den Präsidenten
发明人： Sahin, Ugur , Türeci, Özlem , Koslowski, Michael , Usener, Dirk
CPC分类号： A61K39/0011 , A61K45/06 , A61K2039/5256 , A61K2039/54 , A61K2039/57 , A61K2039/572 , C07K14/4748 , C07K16/2803 , C07K16/30 , C07K2317/34 , C12Q1/6886 , C12Q2600/158 , G01N33/574
摘要： The invention relates to genetic products the expression of which is associated with cancer diseases. The invention also relates to the therapy and diagnosis of diseases in which the genetic products are expressed or aberrantly expressed, in particular cancer diseases.
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30.发明公开Monoclonal antibodies against claudin-18 for treatment of cancer 有权MonoklonaleAntikörpergegen Claudin-18 zur Behandlung von Krebs
公开(公告)号：EP2311879A3
公开(公告)日：2011-05-18
申请号：EP10011776.1
申请日：2006-11-24
申请人： Ganymed Pharmaceuticals AG , Johannes Gutenberg-Universität Mainz, vertreten durch den Präsidenten
发明人： Sahin, Ugur , Türeci, Özlem , Usener, Dirk , Fritz, Stefan , Uherek, Christoph , Brandenburg, Gunda , Geppert, Harald-Gerhard , Schröder, Anja Kristina , Thiel, Philippe
IPC分类号： C07K16/30 , A61K39/395 , A61P35/00 , C12N5/12 , A61K47/48
CPC分类号： C07K16/18 , A61K39/3955 , A61K45/06 , A61K47/6803 , A61K47/6807 , A61K47/6809 , A61K47/6813 , A61K47/6821 , A61K47/6823 , A61K47/6829 , A61K47/6851 , A61K47/6859 , A61K47/6863 , A61K47/6869 , A61K51/1063 , A61K2039/505 , C07K16/28 , C07K16/3046 , C07K2317/14 , C07K2317/24 , C07K2317/51 , C07K2317/515 , C07K2317/56 , C07K2317/565 , C07K2317/73 , C07K2317/732 , C07K2317/734 , C07K2317/76
摘要： The present invention provides antibodies useful as therapeutics for treating and/or preventing diseases associated with cells expressing CLD18, including tumor-related diseases such as gastric cancer, esophageal cancer, pancreatic cancer, lung cancer, ovarian cancer, colon cancer, hepatic cancer, head-neck cancer, and cancer of the gallbladder.
摘要翻译： 本发明提供了可用作治疗和/或预防与表达CLD18的细胞相关的疾病的治疗剂的抗体，包括肿瘤相关疾病如胃癌，食管癌，胰腺癌，肺癌，卵巢癌，结肠癌，肝癌，头部 - 癌症和胆囊癌。
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