-
公开(公告)号：EP2438064A1
公开(公告)日：2012-04-11
申请号：EP10721029.6
申请日：2010-06-02
申请人： Novartis AG
IPC分类号： C07D471/04 , C07D471/14 , A61K31/437 , A61K31/4375 , A61P35/00
CPC分类号： C07D471/04 , C07D471/14 , C07D498/04
摘要： The invention relates to the use of 1H-imidazo[4,5-c]quinolinone derivatives and salts thereof in the treatment of protein and/or lipid kinase dependent diseases and for the manufacture of pharmaceutical preparations for the treatment of said diseases; 1H-imidazo[4,5-c] quinolinone derivatives for use in the treatment of protein and/or lipid kinase dependent diseases; a method of treatment against said diseases, comprising administering the 1H- imidazo[4,5-c] quinofinone derivatives to a warm-blooded animal, especially a human; pharmaceutical preparations comprising an 1H-imidazo[4,5-c] quinolinone derivative, especially for the treatment of a protein and/or lipid kinase dependent disease; novel 1 H- imidazo[4,5-c] quinolinone derivatives; and a process for the preparation of the novel 1H- imidazo[4,5-c] quinolinone derivatives.
-
22.发明公开1H-IMIDAZO[4,5-C]QUINOLINONE COMPOUNDS, USEFUL FOR THE TREATMENT OF PROLIFERATIVE DISEASES 审中-公开于治疗增殖疾病SUITABLE -1H-咪唑并[4,5-C]喹啉酮化合物
公开(公告)号：EP2438063A1
公开(公告)日：2012-04-11
申请号：EP10720790.4
申请日：2010-06-02
申请人： Novartis AG
IPC分类号： C07D471/04 , C07D471/14 , A61K31/4353 , A61K31/4745 , A61P35/00
CPC分类号： C07D471/04 , C07D471/14
摘要： The invention relates to the use of 1
H -imidazo[4,5-
c ]quinolinone compounds and salts thereof in the treatment of protein and/or lipid kinase dependent diseases and for the manufacture of pharmaceutical preparations for the treatment of said diseases; 1
H -imidazo[4,5-
c ]quinolinone compounds for use in the treatment of protein and/or lipid kinase dependent diseases; a method of treatment against said diseases, comprising administering the 1
H -imidazo[4,5-
c ]quinolinone compounds to a warm-blooded animal, especially a human; pharmaceutical preparations comprising an 1
H -imidazo[4,5-
c ]quinolinone compounds, especially for the treatment of a protein and/or lipid kinase dependent disease; novel 1
H -imidazo[4,5-
c ]quinolinone compounds; and a process for the preparation of the novel 1
H -imidazo[4,5-
c ]quinolinone compounds.-
公开(公告)号：EP2049502B1
公开(公告)日：2012-01-04
申请号：EP07819913.0
申请日：2007-07-25
申请人： Novartis AG
发明人： STAUFFER, Frédéric , FURET, Pascal
IPC分类号： C07D239/74 , C07D239/84 , C07D401/04 , C07D405/04 , C07D401/14 , C07D409/04 , C07D403/04 , C07D409/14 , A61K31/517 , A61P29/02 , A61P35/00 , A61P37/08
CPC分类号： C07D239/74 , C07D239/84 , C07D401/04 , C07D401/14 , C07D403/04 , C07D405/04 , C07D409/04 , C07D409/14
摘要： The invention relates to compounds of the formula (I), which are appropriate for the treatment of kinase, e.g. PI3K-related, diseases, such as proliferative diseases, inflammatory diseases, obstructive airways disorders and transplantation related diseases.
-
24.发明公开IMIDAZO [1,2-B]PYRIDAZINE DERIVATIVES FOR THE TREATMENT OF C-MET TYROSINE KINASE MEDIATED DISEASE 审中-公开咪唑并[1,2-B]哒嗪用于治疗由c-Met的酪氨酸激酶介导的疾病
公开(公告)号：EP2265614A1
公开(公告)日：2010-12-29
申请号：EP09714429.9
申请日：2009-02-26
申请人： Novartis AG
发明人： FURET, Pascal , MCCARTHY, Clive , SCHOEPFER, Joseph , SPANKA, Carsten , STANG, Melanie , STAUFFER, Frédéric
IPC分类号： C07D487/04 , A61K31/5025 , A61P35/00
CPC分类号： C07D487/04 , C07D519/00
摘要： The invention relates to compounds of formula (I) and salts thereof, formula (I) wherein the substituents are as defined in the specification, the application of a compound of formula (I) in a process for the treatment of the human or animal body, in particular with regard to C-Met tyrosine kinase mediated disease; the use of a compound of formula (I) for manufacturing a medicament for the treatment of such diseases; pharamaceutical compositions comprising a compound of the formula (I), optionally in the presence of a combination partner; processes for the preparation of a compound of formula (I).
-
-
-
搜索结果
24 条记录 (耗时 0.032 秒)
