公开(公告)号：EP2630470B1

公开(公告)日：2017-03-29

申请号：EP11791077.8

申请日：2011-10-21

Applicant: SpectraSensors, Inc.

Inventor： LIU, Xiang ,  LEWISON, John ,  JI, Wenhai ,  FEITISCH, Alfred

IPC: G01N21/35 ,  G01N21/61 ,  G01N21/31 ,  G01N21/39 ,  G01N21/03 ,  G01N21/3504 ,  G01N21/27 ,  G01N21/3518 ,  G01J3/28 ,  G01J3/42

CPC classification number: G01J3/28 ,  G01J3/42 ,  G01N21/031 ,  G01N21/274 ,  G01N21/31 ,  G01N21/3504 ,  G01N21/3518 ,  G01N21/39 ,  G01N2021/399

公开(公告)号：EP2630470A1

公开(公告)日：2013-08-28

申请号：EP11791077.8

申请日：2011-10-21

Applicant: SpectraSensors, Inc.

Inventor： LIU, Xiang ,  LEWISON, John ,  JI, Wenhai ,  FEITISCH, Alfred

IPC: G01N21/35 ,  G01N21/61 ,  G01N21/31 ,  G01N21/39

CPC classification number: G01J3/28 ,  G01J3/42 ,  G01N21/031 ,  G01N21/274 ,  G01N21/31 ,  G01N21/3504 ,  G01N21/3518 ,  G01N21/39 ,  G01N2021/399

Abstract: A reference harmonic absorption curve of a laser absorption spectrometer, which can include a tunable or scannable laser light source and a detector, can have a reference curve shape and can include a first, second, or higher order harmonic signal of a reference signal generated by the detector in response to light passing from the laser light source through a reference gas or gas mixture. The reference gas or gas mixture can include one or more of a target analyte and a background gas expected to be present during analysis of the target analyte. The reference harmonic absorption curve can have been determined for the laser absorption spectrometer in a known or calibrated state. A test harmonic absorption curve having a test curve shape is compared with the reference harmonic absorption curve to detect a difference between the test curve shape and the reference curve shape that exceeds a predefined allowed deviation and therefore indicates a change in an output of the laser light source relative to the known or calibrated state. One or more operating and/or analytical parameters of the laser absorption spectrometer are adjusted to correct the test curve shape to reduce the difference between the test curve shape and the reference curve shape.

公开(公告)号：EP2630469A1

公开(公告)日：2013-08-28

申请号：EP11711169.0

申请日：2011-02-15

Applicant: SpectraSensors, Inc.

Inventor： FEITISCH, Alfred ,  KELLER, Lutz ,  LIU, Xiang ,  SCHREMPEL, Mathias ,  HELBLEY, Keith, Benjamin

IPC: G01N21/35 ,  G01N21/61

CPC classification number: G01J3/28 ,  G01J3/42 ,  G01N21/031 ,  G01N21/274 ,  G01N21/31 ,  G01N21/3504 ,  G01N21/3518 ,  G01N21/39 ,  G01N2021/399

Abstract: A valid state of an analytical system that includes a light source and a detector can be verified by determining that deviation of first light intensity data quantifying a first intensity of light received at the detector from the light source after the light has passed at least once through each of a reference gas in a validation cell and a zero gas from a stored data set does not exceed a pre-defined threshold deviation. The stored data set can represent at least one previous measurement collected during a previous instrument validation process performed on the analytical system. The reference gas can include a known amount of an analyte. A concentration of the analyte in a sample gas can be determined by correcting second light intensity data quantifying a second intensity of the light received at the detector after the light passes at least once through each of the reference gas in the validation cell and a sample gas containing an unknown concentration of the analyte compound. Related systems, methods, and articles of manufacture are also described.

Abstract translation: 包括光源和检测器的分析系统的有效状态可以通过确定在光已经通过至少一次通过之后量化在检测器处接收的第一光强度的光的第一光强数据的偏差与光源 验证单元中的参考气体和来自存储的数据组的零气体中的每一个不超过预定义的阈值偏差。 存储的数据集可以表示在分析系统上执行的先前的仪器验证过程期间收集的至少一个以前的测量。 参考气体可以包括已知量的分析物。 样品气体中分析物的浓度可以通过校正第二光强度数据来确定，该第二光强度数据在光通过至少一次通过验证单元中的每个参考气体之后，量化在检测器处接收的光的第二强度，并且样品气体 含有未知浓度的分析物。 还描述了相关系统，方法和制品。