公开(公告)号：EP2091516A2

公开(公告)日：2009-08-26

申请号：EP07874325.9

申请日：2007-11-30

申请人： Anterios, Inc.

发明人： EDELSON, Jonathan ,  KOTYLA, Timothy

IPC分类号： A61K9/107 ,  A61K9/10 ,  A61K9/06 ,  A61K8/06 ,  A61K38/00

CPC分类号： A61K8/068 ,  A61K8/0241 ,  A61K8/044 ,  A61K8/064 ,  A61K8/11 ,  A61K8/64 ,  A61K8/92 ,  A61K9/14 ,  A61K38/08 ,  A61K38/2207 ,  A61K2800/413 ,  A61Q1/06 ,  A61Q17/04 ,  A61Q19/00 ,  A61Q19/08 ,  B82Y5/00

摘要： The present invention provides nanoparticle compositions including one or more peptides. The present invention achieves transdermal delivery of such peptides without the need for peptide modification, or for use of chemical or mechanical abrasion or disruption of skin.

摘要翻译： 本发明提供包含一种或多种肽的纳米颗粒组合物。 本发明实现了这种肽的透皮递送，而不需要肽修饰，或用于化学或机械磨损或皮肤破坏。

公开(公告)号：EP2015773A2

公开(公告)日：2009-01-21

申请号：EP07861297.5

申请日：2007-04-27

申请人： Anterios, Inc.

发明人： EDELSON, Jonathan

IPC分类号： A61K39/02

CPC分类号： G01N33/5088 ,  G01N33/944 ,  G01N2333/33

摘要： The present invention provides methods for assessing the activity of topically administered chemodenervating agents. In some embodiments, methods for assessing the activity of topically administered chemodenervating agents involve determining the extent of inhibition of acetylcholine release near the site of administration. In some embodiments, methods for assessing activity of topically administered chemodenervating agents involve observing a reflex motion of a limb of a subject.