公开(公告)号：EP4205762A1

公开(公告)日：2023-07-05

申请号：EP21875809.2

申请日：2021-09-30

Applicant: OSAKA UNIVERSITY ,  Takara Bio Inc. ,  AnGes, Inc.

Inventor： NAKAGAMI, Hironori ,  MORISHITA, Ryuichi ,  HAYASHI, Hiroki ,  AMAISHI, Yasunori ,  OKAMOTO, Sachiko ,  MINENO, Junichi ,  IKAI, Hisato ,  MICHIBATA, Junko ,  KOMATSUNO, Takao

IPC: A61K39/215 ,  A61K39/39 ,  A61P31/14 ,  C12N15/50 ,  C12N15/63 ,  C12N15/86 ,  A61K35/76 ,  A61K31/711

Abstract: Provided is DNA that: encodes a coronavirus (SARS CoV-2) spike protein or a fragment thereof; and has been optimized to partially or fully exhibit a codon included in a DNA sequence.

公开(公告)号：EP2174666B1

公开(公告)日：2013-12-18

申请号：EP08765314.3

申请日：2008-06-09

Applicant: Daiichi Sankyo Company, Limited ,  Osaka University

Inventor： MORISHITA, Ryuichi ,  SATO, Naoyuki ,  TAKEDA, Shuko

IPC: A61K31/41 ,  A61K31/4178 ,  A61K31/4184 ,  A61K31/454 ,  A61P25/28 ,  A61P43/00

CPC classification number: A61K31/41 ,  A61K31/4178 ,  A61K31/4184 ,  A61K31/454

Abstract: The present invention provides a medicament for preventing or treating Alzheimer's disease or mild cognitive impairment which is an early state of cognitive impairment including Alzheimer's disease, comprising an angiotensin II receptor blocker as an active ingredient. A prophylactic or therapeutic agent for Alzheimer's disease or mild cognitive impairment which is an early state of cognitive impairment including Alzheimer's disease, comprising an angiotensin II receptor blocker as an active ingredient.

公开(公告)号：EP2168599A1

公开(公告)日：2010-03-31

申请号：EP08777680.3

申请日：2008-06-27

Applicant: Asubio Pharma Co., Ltd. ,  Osaka University

Inventor： TANIYAMA, Yoshiaki ,  MORISHITA, Ryuichi ,  KATSURAGI, Naruto

IPC: A61K39/395 ,  A61P35/00 ,  A61P35/04 ,  G01N33/574

CPC classification number: C07K16/22 ,  A61K2039/505 ,  C07K16/30 ,  C07K2317/34 ,  C07K2317/73 ,  G01N33/57484

Abstract: The present invention relates to a pharmaceutical composition for cancer treatment, which comprises an antibody against a peptide region encoded by Exon-17 of periostin. More specifically, the present invention relates to a pharmaceutical composition for cancer treatment, which comprises an anti-periostin antibody recognizing a splice variant of periostin having anti-cell adhesive properties specifically expressed in interstitial tissue during tissue restructuring such as cancer tissues, or a method and reagent for cancer diagnosis using the above anti-periostin antibody.

Abstract translation: 本发明涉及一种用于癌症治疗，所述抗体针对由外显子-17的骨膜素编码的肽区域包括药物组合物。 更具体地，本发明涉及一种用于癌症治疗的药物组合物，抗骨膜素抗体的方法，包括确认组织重建期间在间质组织中特异性过表达具有骨膜素的抗细胞粘附作用的剪接变体：如癌组织的方法，或者 和试剂使用上述抗骨膜素抗体的癌症的诊断。