摘要:
An apparatus for acoustic or mechanical stimulation of a cochlea and measurement of acoustically or mechanically evoked electrophysiologic responses from the cochlea is provided. In one example, the apparatus includes an acoustic stimulator for generating an acoustic signal and an electrophysiologic response measuring device positioned proximal the cochlea or within the cochlea for measuring an acoustically evoked electrophysiologic response to the acoustic signal. Methods of utilizing the apparatus for diagnostic and therapeutic procedures related to hearing impairment are also provided.
摘要:
A method for monitoring the depth of anesthesia experienced by a patient includes identifying a change in one or more evoked bio-potentials (100) using a wavelet transform, and calculating at least one index (108) indicative of the depth of anesthesia experienced by the patient based on the changes in the evoked bio-potentials (100) over a period of time during which anesthesia is administered to the patient. Optionally, changes in random electroencephalogram activity, pulse oximetry measurements, and blood gas measurements are combined with the changes in the evoked bio-potentials (100) in calculations of the index. The resulting indices are optionally displayed in a graphical representation (110) of the level of anesthesia experienced by the patient.
摘要:
A method for monitoring blood flow in at least one region of cerebral vasculature of a subject, the method comprising determining an electrophysiological activity in the at least one region of the cerebral vasculature using a non-invasive technique; determining a deviation of the electrophysiological activity from a baseline of electrophysiological activity attributed to the at least one region of the cerebral vasculature; and determining the blood flow in specific branches of the at least one region of the cerebral vasculature based on the deviation.
摘要:
Apparatus (10) for evoking and recording bio-potentials from a human subject and methods of use are described. The apparatus (10) includes a flexible member (18) with a layer of conductive material (12) disposed thereon for contacting a skin surface on the human subject. The dimensions and shape of the flexible member (18) are adapted for conforming contact between the conductive material (12) and the skin surface. A stimulus delivery element (28) is coupled to the flexible member (18) for delivering a sensory stimulus to the subject to evoke bio-potentials, which are detected and received through the layer of conductive material (12).
摘要:
A portable hand-held electrical testing device (10) including a processor (40) housed within an enclosure (12). The processor (40) is configured to operate on commands by a user to process sub-microvolt electrical signals received through an input/output interface (30). The input/output interface (30) includes a capacitive coupled amplifier (52C) with adjustable gain settings. Onboard memory (42) linked to the processor (40) stores processing data and instructions. A display device (16) is mounted to the enclosure (12) and is operatively connected to the processor (40) to display processing results in real time.
摘要:
A disposable electrode array 100, 200 including a flexible member 106, 206 in which a plurality of electrodes 102, 202 are disposed, having a shape adapted to contact the forehead skin surface on a human patient. A pair of ear loops 104, 204 coupled to the disposable electrode array 100, 200 secure the disposable electrode array 100, 200 about the patient's ears, with the flexible member 106, 206 disposed across the patient's bow, retaining the electrodes 102, 202 against the skin surface. Additional electrodes 102, 202 are disposed in proximity to the ear loops 104, 204 and are configured to contact the skin surface behind the patient's ears. An auditory stimulus delivery element 116, 216 is coupled with each of the ear loops 104, 204, and positioned to seat in proximity to the patient's ear canal for the delivery of auditory stimulus. Electrical conductors associated with the electrodes 102, 202 and the stimulus delivery elements 116, 216 are routed within the flexible member 106, 206 to a common external connection point 118, 218 for connection to an external system. The disposable electrode array 100, 200 may be configured for both evoking and measuring evoked bio-potentials in the human subject, or for measuring bio-potentials evoked using a separate stimulus delivery system.
摘要:
A method for monitoring the depth of anesthesia experienced by a patient includes identifying a change in one or more evoked bio-potentials (100) using a wavelet transform, and calculating at least one index (108) indicative of the depth of anesthesia experienced by the patient based on the changes in the evoked bio-potentials (100) over a period of time during which anesthesia is administered to the patient. Optionally, changes in random electroencephalogram activity, pulse oximetry measurements, and blood gas measurements are combined with the changes in the evoked bio-potentials (100) in calculations of the index. The resulting indices are optionally displayed in a graphical representation (110) of the level of anesthesia experienced by the patient.
摘要:
Apparatus (10) for evoking and recording bio-potentials from a human subject and methods of use are described. The apparatus (10) includes a flexible member (18) with a layer of conductive material (12) disposed thereon for contacting a skin surface on the human subject. The dimensions and shape of the flexible member (18) are adapted for conforming contact between the conductive material (12) and the skin surface. A stimulus delivery element (28) is coupled to the flexible member (18) for delivering a sensory stimulus to the subject to evoke bio-potentials, which are detected and received through the layer of conductive material (12).
摘要:
A method and system for combining active and passive neuromonitoring methods to measure biopotential signals in sedated ICU patients over the entire range of sedation from fully alert to the suppression of EEG. The system utilizes an integrated sensor that includes a sound generator and a plurality of EEG electrodes on a single, lightweight disposable component. The method of the present invention utilizes a control unit for switching between active and passive monitoring methods, depending upon the level of sedation. The control unit displays the results of active monitoring during levels of consciousness and light sedation and displays the results of passive monitoring during levels of deep sedation.
摘要:
The invention relates to a device for controlled modulation of physiological and pathological neuronal rhythmic activity in the brain by means of sensory stimulation, which is capable of diagnostically ascertaining functional disorders in the brain and of alleviating or eliminating the symptoms of a functional disruption. According to the invention, the device comprises a control unit (4), a stimulator (1) and at least one means for detecting brain activity, said means being connected to the control unit (1).