公开(公告)号：EP1409122A2

公开(公告)日：2004-04-21

申请号：EP01984956.1

申请日：2001-10-31

Applicant: THE BOARD OF TRUSTEES OFTHE LELAND STANFORD JUNIOR UNIVERSITY

Inventor： TROST, Barry, M. ,  ITO, Hisanaka

IPC: B01J2/00

CPC classification number: C07C45/64 ,  B01J23/06 ,  B01J31/1805 ,  B01J31/182 ,  B01J2231/342 ,  B01J2231/345 ,  B01J2231/40 ,  B01J2531/20 ,  B01J2531/22 ,  B01J2531/23 ,  B01J2531/26 ,  B01J2531/27 ,  C07B53/00 ,  C07B2200/07 ,  C07C45/72 ,  C07C45/74 ,  C07C201/12 ,  C07C201/14 ,  C07C269/06 ,  C07C2601/14 ,  C07D207/09 ,  C07C49/83 ,  C07C271/16 ,  C07C205/15 ,  C07C205/16 ,  C07C205/30 ,  C07C205/32 ,  C07C205/14 ,  C07C205/26

Abstract: Methods and compositions are provided for the direct catalytic asymmetric aldol reaction of aldehydes with donor molecules selected from ketones and nitroalkyl compounds. The reactions employ as catalyst a Group 2A or Group 2B metal complex of a ligand of formula (I), as defined further herein.

Abstract translation: 提供了方法和组合物用于醛与选自酮和硝基烷基化合物的供体分子的直接催化不对称醛醇缩合反应。 反应采用如本文进一步定义的式I配体的2A族或2B族金属络合物作为催化剂。

公开(公告)号：EP0988276A1

公开(公告)日：2000-03-29

申请号：EP98923896.9

申请日：1998-06-02

Applicant: EASTMAN CHEMICAL COMPANY

Inventor： BOAZ, Neil, W.

IPC: C07C201/12 ,  C07C205/11 ,  C07C205/45 ,  C07C319/14 ,  C07C323/22

CPC classification number: C07C201/12 ,  C07C45/27 ,  C07C45/32 ,  C07C201/14 ,  C07C319/14 ,  C07C323/22 ,  C07C205/11 ,  C07C205/45

Abstract: The preparation of aromatic ketones substituted with a thioether group at the ortho position is accomplished by the initial reaction of an aromatic nucleus substituted with a halide and an ortho nitro group with a nitroalkane in the presence of a hydroxide base. The resulting ortho-nitroalkyl nitroarene compound is converted to the corresponding ortho-nitroaryl ketone by an oxidative Nef reaction. The aromatic nitro group of the ortho-nitroaryl ketone is replaced with a thioether group by reaction with a thiolate anion, most preferably under phase-transfer conditions. Aromatic ketones may be used to prepare various pharmaceutical and herbicidal compounds.

公开(公告)号：EP0402485A4

公开(公告)日：1991-01-23

申请号：EP90901095

申请日：1989-12-22

Applicant: ANDRIEVSKY, ALEXANDR MIKHAILOVICH ,  GORELIK, MIKHAIL VIKTOROVICH ,  AVIDON, SERGEI VIKTOROVICH ,  GORDIEVSKAYA, EVGENIA VASILIEVNA ,  ALTMAN, ELENA SHULIMOVNA ,  VOROZHTSOV, GEORGY NIKOLAEVICH ,  DJUMAEV, KIRILL MIKHAILOVICH

Inventor： ANDRIEVSKY, ALEXANDR MIKHAILOVICH ,  GORELIK, MIKHAIL VIKTOROVICH ,  AVIDON, SERGEI VIKTOROVICH ,  GORDIEVSKAYA, EVGENIA VASILIEVNA ,  ALTMAN, ELENA SHULIMOVNA ,  VOROZHTSOV, GEORGY NIKOLAEVICH ,  DJUMAEV, KIRILL MIKHAILOVICH

IPC: C07C201/14 ,  C07C205/12 ,  C07B39/00 ,  C07B43/02 ,  C07C201/06 ,  C07C201/08

CPC classification number: C07C201/14 ,  C07C205/12

公开(公告)号：EP0083417B1

公开(公告)日：1984-09-12

申请号：EP82111074.9

申请日：1982-12-01

Applicant: HOECHST AKTIENGESELLSCHAFT

Inventor： Wykypiel, Werner, Dr. ,  Tronich, Wolfgang, Dr.

IPC: C07C79/46 ,  C07C76/02

CPC classification number: C07C201/14 ,  C07C205/57