Methods and devices for producing biomolecules
    31.
    发明公开
    Methods and devices for producing biomolecules 审中-公开
    Verfahren und Vorrichtungen zur Herstellung vonBiomolekülen

    公开(公告)号:EP2088196A1

    公开(公告)日:2009-08-12

    申请号:EP08151209.7

    申请日:2008-02-08

    IPC分类号: C12N15/10 B01D1/24

    摘要: A scalable process and device for producing a biomolecule, in particular pharmaceutical grade plasmid DNA is described. The process includes the steps of alkaline lysis, neutralization and clarification and can be further extended. For separating the lysate and the precipitate an improved floatation method is disclosed. This method is based on attachment of CO 2 bubbles on the precipitate floc. The CO 2 is released from a carbonate salt during or after neutralization (acidification). The method of the invention is preferably carried out in an automated continuous mode applying devices for lysis and neutralization and a novel device for completely continuous clarification (separation of flocs and clarified lysate).

    摘要翻译: 描述了用于生产生物分子,特别是药物级质粒DNA的可扩展的方法和装置。 该方法包括碱裂解,中和和澄清的步骤,并可进一步延长。 为了分离裂解物和沉淀物,公开了改进的浮选方法。 这种方法是基于沉淀絮凝物上CO 2气泡的附着。 中和(酸化)期间或之后,CO 2从碳酸盐中释放出来。 本发明的方法优选以自动连续模式施加用于裂解和中和的装置和用于完全连续澄清(分离絮凝物和澄清裂解物)的新装置进行。

    DISTRIBUTOR PLATE AND EVAPORATOR
    33.
    发明公开
    DISTRIBUTOR PLATE AND EVAPORATOR 失效
    分销地面和蒸发器的

    公开(公告)号:EP0713411A4

    公开(公告)日:1997-03-05

    申请号:EP94923590

    申请日:1994-08-09

    发明人: WALKER MICHAEL

    摘要: The invention relates to a distributor plate (9) for a falling film evaporator (1-5) the distributor plate (9) including an essentially planar plate member (45) having a multiplicity of distribution holes (46) therein, the distributor plate (9) being adapted to maintain a head of liquid thereon during evaporation to thereby regulate flow and distribution of liquid to be evaporated to calandria (8) via said distribution holes; the distributor plate (9) further comprising a series of overflow conduits (47) for providing additional flow of liquid through the plate during washing the inlets of the overflow conduits being disposed above the surface of the plate member to provide an overflow of wash liquid during washing. The invention also provides a method of operating a multiple effect evaporator in which the effects include the distributor plate (9).

    Process for producing powdery anionic surfactant
    34.
    发明公开
    Process for producing powdery anionic surfactant 失效
    一种用于粉状,阴离子表面活性剂的制备方法。

    公开(公告)号:EP0572957A3

    公开(公告)日:1994-12-07

    申请号:EP93108713.4

    申请日:1993-05-28

    申请人: KAO CORPORATION

    摘要: The process for producing a powdery anionic surfactant according to the present invention, wherein a powdery anionic surfactant is produced by using an evaporator having a heat transfer wall and rotating blades rotating along the inner surface of the heat transfer wall, which comprises feeding the anionic surfactant in the form of an aqueous slurry thereof having a solid concentration of from 60 to 80 wt.% into the evaporator, forming a film of the anionic surfactant on the inner surface of the heat transfer wall by rotating the blades, and scraping the film from the inner heat transfer wall with the rotating blades and powdering while continuously concentrating and drying the aqueous anionic surfactant slurry.

    Dünnschicht-Kontakttrockner
    36.
    发明公开
    Dünnschicht-Kontakttrockner 失效
    薄膜接触机。

    公开(公告)号:EP0009173A1

    公开(公告)日:1980-04-02

    申请号:EP79103289.9

    申请日:1979-09-05

    申请人: BAYER AG

    IPC分类号: B01D1/24 F26B3/26 C09B67/00

    摘要: In einem Trockner werden Verteilerkörper von einer zentralen Drehvorrichtung (2) durch eine Zwangsführung zwischen zueinander parallelen Ebenen (8, 9), die aber nicht senkrecht zur Drehvorrichtungsachse liegen, so bewegt, daß die gesamte Wärmeaustauschfläche des Trockners von den Verteilerkörperkanten überstrichen wird. Dadurch ist eine Selbstreinigung der inneren Oberfläche des Trockners gewährleistet, und es tritt bei zu Klumpen neigenden Produkten eine zusätzliche Mahlung auf. Bevorzugt sind als Verteilerkörper gerade Kreiszylinder; sie sind ohne zusätzliche Führung mit geringem axialem Spiel zwischen den parallelen Ebenen frei beweglich.

    摘要翻译: 在干燥器中歧管体由相互平行的平面(8,9),但不垂直于所述旋转装置轴线移动,使得干燥器的整个热交换表面是由分配器体边缘扫过之间的强制引导是从一个中央转动装置(2)。 干燥器的内表面的这种自清洁得到保障,并且存在在倾向块状的产品的附加研磨。 优选作为分配器体直的圆柱体; 他们可以自由地无需额外的指导移动与平行平面之间的小轴向间隙。

    CIRCULAR RING TYPE DRYING MACHINE
    40.
    发明公开

    公开(公告)号:EP3698860A1

    公开(公告)日:2020-08-26

    申请号:EP18868926.9

    申请日:2018-08-09

    IPC分类号: B01D1/24 B01D1/30

    摘要: The present invention discloses a ring dryer, comprising a housing, a top cover provided at the top of the housing, and a base provided at the bottom of the housing, and further comprising a feeding system into which the material to be dried flows, a material coating assembly, a material extrusion assembly, a discharging scraper, and at least two cylinders with different radii, wherein each of the cylinders is provided with a heat medium flow path inside, an annular groove is formed between the adjacent cylinders, and a material outlet is provided at a free end of the feeding system; the material to be dried in the feeding system flows into the annular groove along the material outlet; the material coating assembly, the material extrusion assembly and the discharging scraper are movably arranged in the annular groove and can move along the annular groove relative to the cylinders; and a blade of the discharging scraper is respectively in contact with an inner circumferential surface of the cylinder and an outer circumferential surface of the adjacent cylinder. The present invention has the advantages in that the drying area of the material to be dried is increased, and the material to be dried does not need to be vigorously stirred by the components of the present invention so as to reduce friction between the material to be dried and the components, thereby extending the service life.