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公开(公告)号:EP4077639B1
公开(公告)日:2024-06-12
申请号:EP20833822.8
申请日:2020-12-17
IPC分类号: C12N5/0783 , A61K41/00
CPC分类号: C12N5/0646 , A61K41/0066 , A61K2239/3120230501 , A61K39/4611 , A61K2239/3820230501 , A61K39/4613 , A61K39/46433 , A61K39/4621
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公开(公告)号:EP4378953A1
公开(公告)日:2024-06-05
申请号:EP22383180.1
申请日:2022-12-02
申请人: Universitat de Barcelona , Institut d'Investigacions Biomèdiques August Pi i Sunyer , Hospital Clínic de Barcelona
发明人: ENGEL ROCAMORA, Pablo , RODRÍGUEZ LOBATO, Luis Gerardo , FERNÁNDEZ DE LARREA RODRÍGUEZ, Carlos José , CARDÚS GRANELL, Oriol
IPC分类号: C07K16/28 , A61P35/00 , C07K14/725 , C12N5/0783 , A61K39/00
CPC分类号: C07K16/2803 , A61P35/00 , A61K2039/50520130101 , A61K2039/50720130101 , A61K2039/57220130101 , C07K2317/62220130101 , C07K2319/0320130101 , C07K2319/3320130101 , C07K14/7051 , C12N2501/0020130101 , C12N5/0636 , A61K2039/515620130101 , A61K39/4631 , A61K39/4611 , A61K39/464429
摘要: The present invention relates to a CD229 targeting moiety, wherein the CD229 targeting moiety is an antibody, F(ab')2, Fab, scFab or scFv. The present invention further provides CARs, nucleic acid, cells, pharmaceutical compositions and kits comprising the CD229 targeting moiety. Lastly, methods of treatment of a CD229-positive cancer, preferably Multiple Myeloma, are also provided.
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公开(公告)号:EP4377464A1
公开(公告)日:2024-06-05
申请号:EP22850491.6
申请日:2022-07-27
发明人: JENSEN, Michael C. , ROSSER, James
IPC分类号: C12N15/62 , C12N5/078 , C12N5/0783 , C12N5/10 , C12N15/67 , C07K19/00 , C12N15/113 , C12N15/861 , C12N15/867
CPC分类号: C07K14/7051 , C12N15/86 , C12N2750/1414320130101 , C12N2740/1604320130101 , C12N2510/0020130101 , C12N5/0636 , C12N15/62 , A61K39/4631 , A61K39/464411 , A61K39/464412 , A61K39/4611
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34.
公开(公告)号:EP4377446A1
公开(公告)日:2024-06-05
申请号:EP22761678.6
申请日:2022-07-28
发明人: JAGASIA, Madan
IPC分类号: C12N5/0783 , A61K35/17 , A61P35/00
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公开(公告)号:EP4377335A1
公开(公告)日:2024-06-05
申请号:EP22777698.6
申请日:2022-07-28
发明人: TAKE, Chihiro , YAMAGUCHI, Akiko , SHAPIRO, Gary
IPC分类号: C07K14/725 , C07K16/30 , C07K14/705 , C07K14/52 , C07K14/54 , A61P35/00 , C12N5/0783 , A61K35/17 , A61K39/00
CPC分类号: C07K14/7051 , C07K16/30 , C07K14/70517 , C07K14/521 , C07K14/5418 , C07K2317/62220130101 , C07K2319/0320130101 , C07K2319/3320130101 , C12N5/0636 , A61P35/00 , C07K16/18 , C12N2510/0020130101 , C07K16/244 , C07K16/24 , A61K2039/50520130101 , A61K2039/54520130101 , C07K2317/7020130101 , A61K45/06 , A61K39/4611 , A61K2239/5420230501 , A61K2239/3820230501 , A61K39/4631 , A61K2239/3120230501 , A61K39/464468
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36.
公开(公告)号:EP3927370B8
公开(公告)日:2024-06-05
申请号:EP20711461.2
申请日:2020-02-18
IPC分类号: A61K39/00 , A61P35/00 , A61P37/04 , C12N5/0784 , C12N5/0783
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公开(公告)号:EP3589729B1
公开(公告)日:2024-05-29
申请号:EP18712421.9
申请日:2018-03-02
IPC分类号: C12N5/0783 , A61K35/26 , A61K39/00 , C07K14/725
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38.
公开(公告)号:EP4370696A1
公开(公告)日:2024-05-22
申请号:EP22841572.5
申请日:2022-07-06
发明人: RAO, Venigalla B. , BATRA, Himanshu
IPC分类号: C12N15/86 , C07K14/005 , C12N7/00 , C12N5/0783
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公开(公告)号:EP4370541A1
公开(公告)日:2024-05-22
申请号:EP22768562.5
申请日:2022-07-14
申请人: 2seventy bio, Inc.
发明人: JARJOUR, Jordan
IPC分类号: C07K14/725 , C07K16/00 , C07K16/28 , A61K35/17 , A61P35/00 , C07K16/30 , C12N5/0783
CPC分类号: C07K2319/0020130101 , C07K14/7051 , C07K16/2803 , C07K16/30 , A61P35/00 , C07K2319/3320130101 , C12N5/0636 , C07K2317/62220130101 , C07K2317/56920130101 , C07K2319/0320130101 , C07K2317/3520130101 , C07K2317/3120130101 , C07K2317/7320130101 , C07K16/2851 , C07K16/2878 , A61K2039/50520130101 , C12N2510/0020130101 , A61K39/464402 , A61K2239/3820230501 , A61K39/4611 , A61K39/464486 , A61K39/464411 , A61K39/464417 , A61K39/4632 , A61K39/464412 , A61K2239/4820230501 , A61K39/4631 , A61K2239/3120230501
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公开(公告)号:EP3562936B1
公开(公告)日:2024-05-22
申请号:EP17821929.1
申请日:2017-12-22
IPC分类号: C12N5/0781 , C12N5/0786 , C12N5/0783 , C12N5/078 , C07K16/06 , C12N5/16 , C07K16/00
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