专利检索 ap:("THE CATHOLIC UNIVERSITY OF AMERICA") AND inv:"RAO, Venigalla B." 第 1 页

1.

发明公开
DESIGN OF BACTERIOPHAGE-BASED ARTIFICIAL VIRUSES FOR HUMAN GENOME REMODELING 审中-实审

公开(公告)号：EP4371564A2

公开(公告)日：2024-05-22

申请号：EP24155130.8

申请日：2021-07-21

申请人： THE CATHOLIC UNIVERSITY OF AMERICA

发明人： RAO, Venigalla B. , ZHU, Jingen

IPC分类号： A61K31/7088

CPC分类号： C12N15/86 , C12N2795/1014320130101 , C12N2795/1014220130101 , C12N15/102 , C12N2795/1012120130101 , C12N7/00 , C12N2310/2020170501

摘要： Described is an "artificial virus" (AV) programmed with biomolecules that can enter human cells and carry out precise human genome modification. The AVs comprise: at least one viral vector, such as bacteriophage T4; at least one therapeutic molecule, such as DNA, RNA, protein and their complex; and a lipid coating. Also described is a method of human genome modification, using such an AV, and a method of program such an AV.

2.

发明公开
UNIVERSAL BACTERIOPHAGE T4 NANOPARTICLE PLATFORM TO DESIGN MULTIPLEX SARS-COV-2 VACCINE CANDIDATES BY CRISPR ENGINEERING 审中-公开

公开(公告)号：EP4263811A1

公开(公告)日：2023-10-25

申请号：EP21905936.7

申请日：2021-12-14

申请人： THE CATHOLIC UNIVERSITY OF AMERICA

发明人： RAO, Venigalla B. , ZHU, Jingen

IPC分类号： C12N7/00 , C12N9/22 , C07K14/005 , A61K39/215 , C12N15/70

3.

发明公开
DESIGN OF BACTERIOPHAGE-BASED ARTIFICIAL VIRUSES FOR HUMAN GENOME REMODELING 审中-公开

公开(公告)号：EP4189096A1

公开(公告)日：2023-06-07

申请号：EP21850710.1

申请日：2021-07-21

申请人： THE CATHOLIC UNIVERSITY OF AMERICA

发明人： RAO, Venigalla B. , ZHU, Jingen

IPC分类号： C12N15/86 , C12N15/113 , C12N9/22 , C12N15/10 , C12N15/88 , A61K48/00 , A61K31/7088

4.

发明公开
DESIGN OF BACTERIOPHAGE-BASED ARTIFICIAL VIRUSES FOR HUMAN GENOME REMODELING 审中-实审

公开(公告)号：EP4371564A3

公开(公告)日：2024-08-21

申请号：EP24155130.8

申请日：2021-07-21

申请人： THE CATHOLIC UNIVERSITY OF AMERICA

发明人： RAO, Venigalla B. , ZHU, Jingen

IPC分类号： A61K31/7088 , C12N7/00 , C12N15/10 , C12N15/86

CPC分类号： C12N15/86 , C12N2795/1014320130101 , C12N2795/1014220130101 , C12N15/102 , C12N2795/1012120130101 , C12N7/00 , C12N2310/2020170501

摘要： Described is an "artificial virus" (AV) programmed with biomolecules that can enter human cells and carry out precise human genome modification. The AVs comprise: at least one viral vector, such as bacteriophage T4; at least one therapeutic molecule, such as DNA, RNA, protein and their complex; and a lipid coating. Also described is a method of human genome modification, using such an AV, and a method of program such an AV.

5.

发明公开
ENGINEERED BACTERIOPHAGE T4 NANOPARTICLES AS A POTENTIAL TARGETED ACTIVATOR OF HIV-1 LATENCY IN CD4+ HUMAN T-CELLS 审中-实审

公开(公告)号：EP4370696A1

公开(公告)日：2024-05-22

申请号：EP22841572.5

申请日：2022-07-06

申请人： THE CATHOLIC UNIVERSITY OF AMERICA

发明人： RAO, Venigalla B. , BATRA, Himanshu

IPC分类号： C12N15/86 , C07K14/005 , C12N7/00 , C12N5/0783

CPC分类号： C12N15/86 , C12N2795/1014320130101 , C07K14/005 , C12N2740/1612220130101 , C12N2795/1014520130101 , C12N5/0636 , C12N2510/0020130101

6.

发明公开
A PROKARYOTIC-EUKARYOTIC HYBRID VIRAL VECTOR FOR DELIVERY OF LARGE CARGOS OF GENES AND PROTEINS INTO HUMAN CELLS 审中-公开

公开(公告)号：EP4017986A1

公开(公告)日：2022-06-29

申请号：EP20855101.0

申请日：2020-08-12

申请人： THE CATHOLIC UNIVERSITY OF AMERICA

发明人： RAO, Venigalla B. , ZHU, Jingen

IPC分类号： C12N15/86 , A61K39/12 , A61K48/00

7.

发明公开
DESIGNING A SOLUBLE FULL-LENGTH HIV-1 GP41 TRIMER 审中-公开
标题翻译：设计全长可溶性HIV-1 GP41三聚体

公开(公告)号：EP2925787A2

公开(公告)日：2015-10-07

申请号：EP13858143.4

申请日：2013-11-27

申请人： THE CATHOLIC UNIVERSITY OF AMERICA

发明人： RAO, Venigalla B. , GAO, Guofen

IPC分类号： C07K19/00 , C07K14/155 , C12N15/62

CPC分类号： C07K14/005 , C07K2319/35 , C07K2319/70 , C07K2319/735 , C12N7/00 , C12N7/02 , C12N2740/16122 , C12N2740/16222 , C12N2795/10122 , C12N2795/10123