-
公开(公告)号：EP1771176A2
公开(公告)日：2007-04-11
申请号：EP05791615.7
申请日：2005-06-30
IPC分类号： A61K31/505 , A61K31/40 , C07D239/70 , C07D487/00 , C07D209/82
CPC分类号： C07D487/04 , C07D209/86 , C07D209/88
摘要： The present invention relates to pyrimidoindole and carbazole compounds represented by Formula (I) which shows inhibitory activity against KSP kinesin. The present invention also related to a method of treating cancer, hyperplasias, restenosis, cardiac hypertrophy, immune disorders, fungal disorders, and inflammation.
-
公开(公告)号：EP1682534A2
公开(公告)日：2006-07-26
申请号：EP04810182.8
申请日：2004-11-02
发明人： BERGNES, Gustave , DHANAK, Dashyant
IPC分类号： C07D403/06 , A61K31/496 , A61K31/506
CPC分类号： C07D403/06
摘要： Compounds useful for treating cellular proliferative diseases and disorders by modulating the activity of KSP are disclosed.
-
公开(公告)号：EP1670456A2
公开(公告)日：2006-06-21
申请号：EP04816899.1
申请日：2004-10-05
发明人： BERGNES, Gustave , DHANAK, Dashyant
IPC分类号： A61K31/35 , A61K31/44 , A61K31/55 , C07D223/10 , C07D311/04 , C07D471/02
CPC分类号： C07D491/052 , C07D405/06
摘要： Compounds useful for treating cellular proliferative diseases and disorders by modulating the activity of KSP are disclosed.
-
公开(公告)号：EP1558588A2
公开(公告)日：2005-08-03
申请号：EP03774548.6
申请日：2003-10-02
发明人： QIAN, XiangPing , BERGNES, Gustave , MORGANS, David, J., Jr. , KNIGHT, Steven David , DHANAK, Dashyant
IPC分类号： C07D249/12
CPC分类号： C07D249/12 , C07D403/04
摘要： 1, 2, 4-Triazole-5-ones useful for treating cellular proliferative diseases and disorders by modulating the activity of KSP are disclosed.
摘要翻译： 公开了用于通过调节KSP活性来治疗细胞增殖性疾病和病症的1,2,4-三唑-5-酮。
-
公开(公告)号：EP1385841A1
公开(公告)日：2004-02-04
申请号：EP02725952.2
申请日：2002-05-07
IPC分类号： C07D403/10 , C07D419/10 , A61K31/41 , A61K31/433 , A61P9/00
CPC分类号： C07D405/12 , C07D207/12 , C07D409/12 , C07D413/12 , C07D417/12
摘要： The present invention relates to sulfonamides, pharmaceutical compositions containing them, and their use as antagonists of urotensin II.
摘要翻译： 本发明涉及磺酰胺，含有它们的药物组合物以及它们作为尾加压素II的拮抗剂的用途。
-
公开(公告)号：EP1385507A1
公开(公告)日：2004-02-04
申请号：EP02731720.5
申请日：2002-05-07
IPC分类号： A61K31/40 , C07D207/12
CPC分类号： C07D207/12 , C07D333/34 , C07D401/12 , C07D403/12 , C07D405/12 , C07D409/12
摘要： The present invention relates to sulfonamides, pharmaceutical compositions containing them, and their use as antagonists of urotensin II.
-
公开(公告)号：EP1379519A1
公开(公告)日：2004-01-14
申请号：EP02728588.1
申请日：2002-03-28
IPC分类号： C07D401/02 , C07D403/02 , A61K31/55 , A61K31/495 , A61K31/50 , A61P9/00
CPC分类号： C07D401/12 , A61K31/497 , C07D403/12
摘要： The present invention relates to pyrrolidine sulfonamide sulfonamides, pharmaceutical compositions containing them and their use as urotensin II antagonists.
摘要翻译： 本发明涉及吡咯烷磺酰胺磺酰胺，含有它们的药物组合物以及它们作为尿压素II拮抗剂的用途。
-
公开(公告)号：EP1379503A1
公开(公告)日：2004-01-14
申请号：EP02725377.2
申请日：2002-03-28
IPC分类号： C07D211/00 , C07D401/02 , C07D403/02 , A61K31/55 , A61K31/445 , A61K31/40 , A61P9/00
CPC分类号： C07D409/14
摘要： The present invention relates to pyrrolidine sulfonamides, pharmaceutical compositions containing them and their use as urotensin II antagonists.
摘要翻译： 本发明涉及吡咯烷磺酰胺，含有它们的药物组合物以及它们作为尿压素II拮抗剂的用途。
-
公开(公告)号：EP1351687A2
公开(公告)日：2003-10-15
申请号：EP01987271.2
申请日：2001-12-05
IPC分类号： A61K31/47 , C07D215/16 , C07D215/38
CPC分类号： C07D215/38 , C07D401/12
摘要： The present invention relates to novel quinolones and their use as urotensin antagonists.
-
公开(公告)号：EP1248607A1
公开(公告)日：2002-10-16
申请号：EP00988185.5
申请日：2000-12-19
IPC分类号： A61K31/18 , A61K31/38 , A61K31/335 , A61K31/44 , A61K31/425 , C07C303/38 , C07C311/21 , C07C311/29 , C07C311/44 , C07D213/89 , C07D271/12 , C07D285/14 , C07D333/34 , C07D333/52 , C07D333/72
CPC分类号： C07D213/70 , C07C311/21 , C07C311/29 , C07D271/12 , C07D285/16 , C07D307/68 , C07D319/18 , C07D333/24 , C07D333/62
摘要： The present invention relates to sulfonamides, pharmaceutical compositions containing them, and their use as antagonists of urotensin II.
摘要翻译： 本发明涉及磺酰胺，含有它们的药物组合物以及它们作为尾加压素II的拮抗剂的用途。
-
-
-
-
-
-
-
-
-
搜索结果
52 条记录 (耗时 0.026 秒)
