Tamper-evident dispenser bottle
    41.
    发明公开
    Tamper-evident dispenser bottle 审中-公开
    防篡改交货瓶

    公开(公告)号:EP2172404A1

    公开(公告)日:2010-04-07

    申请号:EP09075573.7

    申请日:2003-10-28

    IPC分类号: B65D47/26 B65D50/04

    摘要: A dispenser bottle and associated closure has a sifter disposed in the neck thereof, either in the form of castellated vents formed in the interior peripheral edge of the neck or a separate sifter element. A rotatable cap is positioned over the sifter. The cap has holes that align with the vents or holes in the sifter to dispense material from the bottle. A removable lock ring is removeably conjoined to the cap to evidence tampering. One embodiment employs a squeeze tab that is depressed to open the bottle thereby increasing the dexterity required for opening. Another embodiment employs a rotatable sifter that must be held by one hand while the cap is held and rotated relative to the sifter by the other hand. A detent provides resistance to opening.

    Compositions for providing an analgesic effect to the skin
    42.
    发明公开
    Compositions for providing an analgesic effect to the skin 有权
    Zusammensetzungen zurAusübungeines schmerzlindernden Effekts auf die Haut

    公开(公告)号:EP2135622A2

    公开(公告)日:2009-12-23

    申请号:EP09250632.8

    申请日:2009-03-05

    IPC分类号: A61K45/06

    摘要: The present invention is directed to compositions including an amine-containing compound selected from Formula I and Formula II


    wherein R 1 , R 2 , R 3 , R 4 and R 5 independently are selected from the group consisting of hydrogen, C 1 -C 6 alkyl, and C 1 -C 6 hydroxyalkyl; or a cosmetically-acceptable salt thereof; and a sensation-blocking agent, where the compositions provide an analgesic effect to the skin when applied to an area of skin exhibiting at least one symptom of itch, pain, stinging, burning sensations, or the like.

    摘要翻译: 本发明涉及包含选自式I和式II的含胺化合物的组合物,其中R 1,R 2,R 3,R 4和R 5独立地选自氢,C 1 -C 6 烷基和C 1 -C 6羟烷基; 或其美容上可接受的盐; 和感觉阻断剂,其中组合物当施用于表现出瘙痒,疼痛,刺痛,烧灼感等的至少一种症状的皮肤区域时,对皮肤提供镇痛作用。

    SKIN CARE COMPOSITION
    44.
    发明授权
    SKIN CARE COMPOSITION 有权
    皮肤护理

    公开(公告)号:EP1280508B1

    公开(公告)日:2009-08-12

    申请号:EP01935082.6

    申请日:2001-05-04

    IPC分类号: A61Q19/00

    摘要: There are provided compositions which include a retinoid and preferably retinol; a dermatologically active acid; and a volatile base, such as ammonium hydroxide. Another embodiment of the invention includes compositions comprising a retinoid and preferably retinol; a dermatologically active acid; a volatile base; and a second neutralizing agent. There are also provided compositions which include a retinoid, a neutralized ammonium salt of a dermatologically active acid, and optionally a neutralized salt, other than ammonium salt, of an acid. Further provided are methods for reducing fine lines, wrinkles, skin roughness, and pore size and for increasing the clarity of a skin surface, cellular turnover, skin radiance, skin smoothness, skin permeation or collagen synthesis in a mammal in need thereof. Compositions as described above are administered topically to the skin of the animal.