公开(公告)号：EP0489876A4

公开(公告)日：1992-09-02

申请号：EP91908639

申请日：1991-04-04

Applicant: GLAXO INC.

Inventor： LACKEY, JOHN, WILLIAM ,  MOOK, ROBERT ANTHONY JR. ,  PARTRIDGE, JOHN, JOSEPH

IPC: C07C35/06 ,  C07C69/96 ,  C07C205/18 ,  C07C205/41 ,  C07D473/00 ,  C07C67/03

CPC classification number: C07D473/00 ,  C07C35/06 ,  C07C69/96 ,  C07C201/10 ,  C07C201/12 ,  C07C2601/10 ,  C07C205/18 ,  C07C205/41

Abstract: This invention relates to a new process for preparing certain optically active purine substituted cyclopentene derivatives including the antiviral agent, carbovir, and novel intermediates used in this process. In particular, this invention concerns a synthesis of (1R-cis)-4-hydroxymethyl-2-cyclopenten-1-ol, an intermediate in this process.

Abstract translation: 本发明涉及一种制备某些光学活性嘌呤取代的环戊烯衍生物的新方法，包括抗病毒剂，维生素和该方法中使用的新型中间体。 特别地，本发明涉及在该方法中的中间体的（1R-顺式）-4-羟甲基-2-环戊烯-1-醇的合成。

公开(公告)号：EP0151835B1

公开(公告)日：1988-05-11

申请号：EP84300713.9

申请日：1984-02-06

Applicant: UNIROYAL CHEMICAL COMPANY, Inc.

Inventor： Gay, Walter A. ,  Dietrich, Robert F.

IPC: C07C79/12 ,  C07C149/34

CPC classification number: C07C323/00 ,  C07C201/10 ,  C07C205/12

公开(公告)号：EP0112452A3

公开(公告)日：1985-09-18

申请号：EP83110434

申请日：1983-10-19

Applicant: THE DOW CHEMICAL COMPANY

Inventor： Hayes, William Verne

IPC: C07C79/04

CPC classification number: C07C201/10 ,  C07C205/02

Abstract: @ A process of making nitroalkanes which comprises reacting a lower alkanol, e.g. methanol, and nitric acid (HNO 3 ) in the vapor phase in the presence of a catalyst which is an oxide or a salt of a metal of Group II of the periodic table, e.g. calcium chloride.