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    SENSORS HAVING INTEGRATED PROTECTION CIRCUITRY
    57.
    发明公开
    SENSORS HAVING INTEGRATED PROTECTION CIRCUITRY 审中-公开

    公开(公告)号：EP4075135A1

    公开(公告)日：2022-10-19

    申请号：EP22177086.0

    申请日：2018-04-19

    申请人： Illumina, Inc.

    发明人： FUNG, Tracy Helen ,  CAI, Xiuyu ,  KWOK, Lisa ,  TRAN, Hai ,  SAMIEE, Kevan ,  QIANG, Liangliang ,  BOYANOV, Boyan

    IPC分类号： G01N33/543 ,  C12Q1/68 ,  G01N21/62 ,  G01N21/64 ,  G01N21/77 ,  B01L3/00

    摘要： An example sensor includes a detection device, including an optical waveguide, an optical sensor operatively associated with the optical waveguide and a device circuitry, including a reagent electrode, a first embedded metal layer electrically connected to the reagent electrode; and a second embedded metal layer electrically connected to the optical sensor wherein the first embedded metal layer is spaced from the second embedded metal layer by an electrically isolating gap, at least a portion of a passivation layer being in contact with the first embedded metal layer and an input region of the optical waveguide, the at least the portion of the passivation layer having a reaction site at least partially adjacent to the input region of the optical waveguide; and a lid operatively connected to the passivation layer to partially define a flow channel between the lid and the reaction site, wherein the reagent electrode is positioned to be in contact with a reagent to be introduced into the flow channel. A method for performing a sensing operation of a sensor in response to a reaction at the reaction site involving at least some reaction component of the reagent and during the sensing operation, applying an electrical bias that renders the reagent electrode one of an anode or a cathode and the embedded metal layer the other of the cathode or the anode, thereby providing cathodic protection or anodic protection to the embedded metal layer, is also disclosed.