DEVICE WITH REDUCED FLUORESCENCE RANGE NOISE AND METHOD

    公开(公告)号:EP3978908A1

    公开(公告)日:2022-04-06

    申请号:EP21208877.7

    申请日:2018-11-30

    申请人: Illumina, Inc.

    摘要: A device comprising: a structure (260) defining a detector surface (206) for supporting biological or chemical samples; a sensor array (201) comprising light sensors (202), and circuitry to transmit data signals based on photons detected by the light sensors (202); and a guide array comprising light guides (214); wherein light guides (214) of the guide array receive excitation light (101) and
    emissions signal light (501) from the detector surface (206), wherein the light guides (214) extend toward respective light sensors (202) of the sensor array (201) and comprise filter material that blocks the excitation light and permits the emissions signal light to propagate toward the respective light sensors (202), wherein the detector surface (206) includes a reaction recess (210), the reaction recess comprising an index of refraction and a dimension sufficient to cancel background light energy incident on the detector surface in a detection band of the sensor array. A method comprising steps for fabricating the device.