公开(公告)号：EP0814775A1

公开(公告)日：1998-01-07

申请号：EP96910378.0

申请日：1996-03-07

申请人： Vivus, Inc.

发明人： PLACE, Virgil A., 10 Ala Kahua

IPC分类号： A61K38 ,  A61F5 ,  A61K9 ,  A61K31 ,  A61K33 ,  A61K45 ,  A61P9 ,  A61P13 ,  A61P15

CPC分类号： A61F5/41 ,  A61K9/0034 ,  A61M31/00 ,  A61M2210/167 ,  Y10S514/968

摘要： A method is provided for preventing erectile dysfunction, particularly vasculogenic impotence, in a male individual. The method involves periodic administration of a vasoactive agent throughout a 24-hour period. The agent and dosage regimen are selected such that regularly increased blood flow to the penis is achieved, in turn preventing arterial occlusion and vascular deterioration of the muscular fibers of the vessels and collagen fibers of the cavernosal tissue.

公开(公告)号：EP0708620A1

公开(公告)日：1996-05-01

申请号：EP95914769.0

申请日：1995-03-27

申请人： KHOURI BIOMEDICAL RESEARCH, INC.

发明人： KHOURI, Roger, K.

IPC分类号： A61F5 ,  A61H9 ,  A61H19

CPC分类号： A61H19/32 ,  A61F2005/412 ,  A61H9/005 ,  A61H2201/1616 ,  A61H2201/1621 ,  A61H2201/163 ,  A61H2201/165 ,  A61H2205/082 ,  A61M1/0033 ,  A61M1/0092 ,  A61M2209/088 ,  A61M2210/1007 ,  A61M2210/167

摘要： An apparatus and method for healing open wounds through enlargement of soft tissue surrounding said wound is comprised of a dome (12) configured to fit over the wound and at least a portion of the surrounding soft tissue. The dome (12) has a rim (14) with a surface area equal to or greater than the normal area of the dome opening to prevent medical complications caused by excessive pressure to the skin. A gasket (46) or other cushioning material may be provided about the periphery of the dome (12) for patient comfort and improved seal. The dome (12) also includes a vacuum pump (20) with a power source (22), pressure sensor (24), and servomechanism (26) for regulating the pressure within the dome (12) to any one of several protocols using pressures which might temporarily exceed non-damaging levels.

公开(公告)号：EP0614676A1

公开(公告)日：1994-09-14

申请号：EP93307483.3

申请日：1993-09-22

申请人： Helmy, Ali M.

发明人： Helmy, Ali M.

IPC分类号： A61M25/00 ,  A61F2/26 ,  A61M5/00

CPC分类号： A61M25/0075 ,  A61F2/26 ,  A61M5/00 ,  A61M2210/167

摘要： An implantable catheter apparatus for self-administration of drugs to the penis of a human patient comprises
   an elongated catheter (10) having a flexible wall (20) surrounding a lumen (22)
   the catheter having
   a distal portion (31) having a closed distal end and adapted to be placed within the corpus cavernosum of the penis of a human patient, a proximal portion (14) adapted to be implanted in the body of the patient at a location remote from the penis, and an intermediate portion connecting the proximal and distal portions and adapted to be implanted within the body of said patient,
   resealable injection port means (16) located at the proximal end providing fluid access from a source of fluid to the lumen,
   the distal portion of the catheter being provided with longitudinal slits (36) to permit fluid to flow from the lumen to the exterior of said catheter.

摘要翻译： 用于将药物自身给药到人类患者的阴茎的可植入导管装置包括细长导管（10），其具有围绕内腔的柔性壁（20），所述导管具有远侧部分（31），所述远端部分（31）具有封闭的远端 并且适于放置在人类患者的阴茎的海绵体内，适于在远离阴茎的位置植入患者体内的近端部分（14）和连接近端和远端的中间部分 远端部分并且适于植入在所述患者的身体内，位于近端的可重新密封的注射口装置（16）提供从流体源到内腔的流体通路，导管的远端部分设置有纵向狭缝（ 36）以允许流体从内腔流动到所述导管的外部