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公开(公告)号:EP2181670A2
公开(公告)日:2010-05-05
申请号:EP10154124.1
申请日:2002-12-20
发明人: Solem, Jan Otto , Kimblad, Per-Ola , Von Oepen, Randolf , Seibold, Gerd , Michlitsch, Kenneth , Ha, Suk-Woo , Eckert, Karl-Ludwig
CPC分类号: A61F2/2451 , A61F2/07 , A61F2/2481 , A61F2/26 , A61F2002/043 , A61F2002/072 , A61F2002/826 , A61F2002/828 , A61F2002/8483 , A61F2210/0004
摘要: A device for reshaping a mitral valve annulus (25), said device being elongate and having such dimensions as to be insertable into a coronary sinus (24). The device comprises fixing means (22, 23; 22a, 23a) for fixing the ends of the device within the coronary sinus (24); anda shape changing member (20a; 7; 7a; 9) extending between the fixing means (22, 23; 22a, 23a). The shape changing member (20a; 7; 7a; 9) includes a plurality of adjacent structural cells. The device includes resorbable delay means (21 a; 8; 8a; 10) that in a first configuration retrains at least two of said plurality of adjacent structural elements in a first, relatively elongate state of shape (K; D; E) and wherein the delay means in a second configuration releases said at least two adjacent structural elements to assume a second, relatively shortened state of shape (K'; D'; E'), thereby reducing a length of the shape-changing member (20a; 7; 7a; 9). The delay means (21 a; 8; 8a; 10) moves from its first configuration to its second configuration upon resorbtion of the delay means.
摘要翻译: 一种用于重塑二尖瓣环(25)的装置,所述装置是细长的并且具有可插入冠状窦(24)的尺寸。 所述装置包括用于将所述装置的端部固定在冠状窦(24)内的固定装置(22,23; 22a,23a) 以及在所述固定装置(22,23; 22a,23a)之间延伸的形状改变构件(20a; 7; 7a; 9)。 形状改变构件(20a; 7; 7a; 9)包括多个相邻的结构单元。 该装置包括可再吸收的延迟装置(21a; 8; 8a; 10),其以第一构型在第一相对较细长的形状状态(K; D; E)中重新培养所述多个相邻结构元件中的至少两个,并且其中 延迟装置以第二构型释放所述至少两个相邻的结构元件以呈现第二相对缩短的形状状态(K'; D'; E'),从而减小形状改变构件(20a; 7)的长度 ; 7a; 9)。 所述延迟装置(21a; 8; 8a; 10)在所述延迟装置再吸收时从其第一配置移动到其第二配置。
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公开(公告)号:EP1458313B1
公开(公告)日:2010-03-31
申请号:EP02795253.0
申请日:2002-12-20
发明人: SOLEM, Jan Otto Solem , KIMBLAD, Per-Ola , VON OEPEN, Randolf , SEIBOLD, Gerd , MICHLITSCH, Kenneth , HA, Suk-Woo , ECKERT, Karl-Ludwig
IPC分类号: A61F2/24
CPC分类号: A61F2/2451 , A61F2/07 , A61F2/2481 , A61F2/26 , A61F2002/043 , A61F2002/072 , A61F2002/826 , A61F2002/828 , A61F2002/8483 , A61F2210/0004
摘要: A device for reshaping a mitral valve annulus (25), said device being elongate and having such dimensions as to be insertable into a coronary sinus (24). The device comprises fixing means (22, 23; 22a, 23a) for fixing the ends of the device within the coronary sinus (24); anda shape changing member (20a; 7; 7a; 9) extending between the fixing means (22, 23; 22a, 23a). The shape changing member (20a; 7; 7a; 9) includes a plurality of adjacent structural cells. The device includes resorbable delay means (21 a; 8; 8a; 10) that in a first configuration retrains at least two of said plurality of adjacent structural elements in a first, relatively elongate state of shape (K; D; E) and wherein the delay means in a second configuration releases said at least two adjacent structural elements to assume a second, relatively shortened state of shape (K'; D'; E'), thereby reducing a length of the shape-changing member (20a; 7; 7a; 9). The delay means (21 a; 8; 8a; 10) moves from its first configuration to its second configuration upon resorbtion of the delay means.
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公开(公告)号:EP2023858A1
公开(公告)日:2009-02-18
申请号:EP07729281.1
申请日:2007-05-18
发明人: SOLEM, Jan Otto , ALON, David
IPC分类号: A61F2/24
CPC分类号: A61F2/246 , A61B17/0401 , A61B2017/00243 , A61B2017/0437 , A61B2017/0445 , A61B2017/0453 , A61F2/2466 , A61F2220/0016 , A61F2230/0093 , A61F2240/002
摘要: The invention is device and method for reducing regurgitation through a mitral valve. The device and method is directed to an anchor portion for engagement with the heart wall and an expandable valve portion configured for deployment between the mitral valve leaflets. The valve portion is expandable for preventing regurgitation through the mitral valve while allowing blood to circulate through the heart. The expandable valve portion may include apertures for reducing the stagnation of blood. In a preferred configuration, the device is configured to be delivered in two-stages wherein an anchor portion is first delivered and the valve structure is then coupled to the anchor portion. In yet another embodiment, the present invention provides a method of forming an anchor portion wherein a disposable jig is used to mold the anchor portion into a three-dimensional shape for conforming to a heart chamber.
摘要翻译: 本发明是用于减少通过二尖瓣返流的装置和方法。 该装置和方法涉及用于与心脏壁接合的锚定部分(70)和被配置用于在二尖瓣小叶之间展开的可扩张瓣膜部分。 瓣膜部分是可扩张的,以防止通过二尖瓣的反流,同时允许血液循环通过心脏。 可扩张瓣膜部分(76)可以包括用于减少血液停滞的孔。 在优选的构造中,该装置被构造成以两阶段递送,其中首先递送锚部分,然后将瓣膜结构连接至锚部分。 在又一个实施例中,本发明提供了一种形成锚固部分的方法,其中使用一次性夹具将锚固部分成型为三维形状以符合心脏腔室。
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公开(公告)号:EP1871300A1
公开(公告)日:2008-01-02
申请号:EP06724472.3
申请日:2006-04-20
发明人: SOLEM, Jan Otto
IPC分类号: A61F2/24
CPC分类号: A61F2/2442 , A61B2017/0412 , A61F2/2403 , A61F2/2412 , A61F2/2418 , A61F2/2427 , A61F2/2457 , A61F2/246 , A61F2/2466 , A61F2210/0014 , A61F2220/0008 , A61F2220/0016 , A61F2230/0054 , A61F2310/00017 , A61F2310/00023
摘要: A blood flow controlling apparatus (42) comprising: a valve means (52), the valve means movable between an open state and a closed state, the valve means in the open state extending primarily in a direction along blood flow, the valve means in the closed state extending in a direction transverse to blood flow, the valve means including a plurality of flaps (344) arranged side-by-side with adjacent surfaces having coaptation areas in close contact with each other to prevent leakage between the flaps; an anchoring means (54) arranged to fix the position of the apparatus in a circulatory system, the anchoring means disposed on an outflow side of the valve means; and an elongate connecting means (46) extending between the valve means and the anchoring means, the connecting means axially spacing the valve means from the anchoring means.
摘要翻译: 一种血流控制装置(42),包括:阀装置(52),所述阀装置在打开状态和关闭状态之间可移动,所述阀装置处于主要沿着血流的方向延伸的打开状态,所述阀装置 所述关闭状态沿横向于血流的方向延伸,所述阀装置包括多个彼此并排布置的折板(344),相邻表面具有彼此紧密接触的接合区域,以防止所述襟翼之间的泄漏; 锚定装置(54),其布置成将所述装置的位置固定在循环系统中,所述锚固装置设置在所述阀装置的流出侧; 以及在阀装置和锚定装置之间延伸的细长连接装置(46),连接装置将阀装置与锚定装置轴向间隔开。
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公开(公告)号:EP1806111A3
公开(公告)日:2007-07-18
申请号:EP07104710.4
申请日:2001-09-08
CPC分类号: A61F2/2451 , A61F2/88 , A61F2/90 , A61F2/91 , A61F2002/075 , A61F2220/0008 , A61F2230/0078
摘要: A device for treatment of mitral annulus dilation comprising an elongate body (8') formed by a solid wire in the shape of an open U-shaped ring adapted to engage the wall of a coronary sinus (5) most adjacent to the mitral valve annulus when inserted into the coronary sinus; the elongate body consisting of a memory metal material which will bend when reverting to its original shape.
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公开(公告)号:EP1796597A2
公开(公告)日:2007-06-20
申请号:EP05798755.4
申请日:2005-09-14
发明人: ZAKAY, Avraham , ROTTENBERG, Dan , MISHALY, David , ALON, David
IPC分类号: A61F2/24
CPC分类号: A61F2/246 , A61B17/00234 , A61B17/12013 , A61B2017/00783 , A61B2017/00867 , A61F2/2412 , A61F2/2466 , A61F2210/0014 , A61F2210/0061 , A61F2210/0066
摘要: In one embodiment, the present invention provides a prosthesis that can be implanted within a heart to at least partially block gaps that may be present between the two mitral valve leaflets. In one preferred embodiment, the prosthesis includes an anchoring ring that expands within the left atrium to anchor the prosthesis and a pocket member fixed to the anchoring ring. The pocket member is positioned within the mitral valve, between the leaflets so that an open end of the pocket member is positioned within the left ventricle. When the mitral valve is open, blood flows past the pocket member, maintaining the pocket member in a collapsed state. When the mitral valve closes, the backpressure of the blood pushes into the pocket member, expanding the pocket member to an inflated shape. The mitral valve leaflets contact the expanded pocket member, allowing the prosthesis to block at least a portion of the openings between the leaflets, thereby minimizing regurgitated blood flow into the left atrium.
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