公开(公告)号：EP2181669A2

公开(公告)日：2010-05-05

申请号：EP10154122.5

申请日：2002-12-20

申请人： Edwards Lifesciences AG

发明人： Solem, Jan Otto ,  Kimblad, Per-Ola ,  Von Oepen, Randolf ,  Seibold, Gerd ,  Michlitsch, Kenneth ,  Ha, Suk-Woo ,  Eckert, Karl-Ludwig

IPC分类号： A61F2/24

CPC分类号： A61F2/2451 ,  A61F2/07 ,  A61F2/2481 ,  A61F2/26 ,  A61F2002/043 ,  A61F2002/072 ,  A61F2002/826 ,  A61F2002/828 ,  A61F2002/8483 ,  A61F2210/0004

摘要： Device for treating mitral insufficiency and a method for producing the device. The device comprises a proximal stent section (222); a distal stent section (224); a central stent section (226) interconnecting said proximal stent section (222) and said distal stent section (226); and at least one biodegradable structure (228), disposed on the central stent section (226). Said proximal stent section (222) and said distal stent section (226) being radially expandable by deployment of said device. Moreover said biodegradable structure (228) is arranged to retain the central section (226) in a contracted shape for a predetermined period after deployment of the device.

摘要翻译： 用于治疗二尖瓣功能不全的装置及其制造方法。 所述装置包括近端支架部分（222）; 远端支架部分（224）; 互连所述近端支架部分（222）和所述远端支架部分（226）的中心支架部分（226）; 以及设置在中心支架部分（226）上的至少一个生物可降解结构（228）。 所述近端支架部分（222）和所述远侧支架部分（226）通过所述装置的展开而可径向扩张。 此外，所述可生物降解结构（228）布置成在部署装置之后将中心部分（226）保持在收缩形状预定的时间段。

公开(公告)号：EP2181670A2

公开(公告)日：2010-05-05

申请号：EP10154124.1

申请日：2002-12-20

申请人： Edwards Lifesciences AG

发明人： Solem, Jan Otto ,  Kimblad, Per-Ola ,  Von Oepen, Randolf ,  Seibold, Gerd ,  Michlitsch, Kenneth ,  Ha, Suk-Woo ,  Eckert, Karl-Ludwig

IPC分类号： A61F2/24 ,  A61F2/84

CPC分类号： A61F2/2451 ,  A61F2/07 ,  A61F2/2481 ,  A61F2/26 ,  A61F2002/043 ,  A61F2002/072 ,  A61F2002/826 ,  A61F2002/828 ,  A61F2002/8483 ,  A61F2210/0004

摘要： A device for reshaping a mitral valve annulus (25), said device being elongate and having such dimensions as to be insertable into a coronary sinus (24). The device comprises fixing means (22, 23; 22a, 23a) for fixing the ends of the device within the coronary sinus (24); anda shape changing member (20a; 7; 7a; 9) extending between the fixing means (22, 23; 22a, 23a). The shape changing member (20a; 7; 7a; 9) includes a plurality of adjacent structural cells. The device includes resorbable delay means (21 a; 8; 8a; 10) that in a first configuration retrains at least two of said plurality of adjacent structural elements in a first, relatively elongate state of shape (K; D; E) and wherein the delay means in a second configuration releases said at least two adjacent structural elements to assume a second, relatively shortened state of shape (K'; D'; E'), thereby reducing a length of the shape-changing member (20a; 7; 7a; 9). The delay means (21 a; 8; 8a; 10) moves from its first configuration to its second configuration upon resorbtion of the delay means.

摘要翻译： 一种用于重塑二尖瓣环（25）的装置，所述装置是细长的并且具有可插入冠状窦（24）的尺寸。 所述装置包括用于将所述装置的端部固定在冠状窦（24）内的固定装置（22,23; 22a，23a） 以及在所述固定装置（22,23; 22a，23a）之间延伸的形状改变构件（20a; 7; 7a; 9）。 形状改变构件（20a; 7; 7a; 9）包括多个相邻的结构单元。 该装置包括可再吸收的延迟装置（21a; 8; 8a; 10），其以第一构型在第一相对较细长的形状状态（K; D; E）中重新培养所述多个相邻结构元件中的至少两个，并且其中 延迟装置以第二构型释放所述至少两个相邻的结构元件以呈现第二相对缩短的形状状态（K'; D'; E'），从而减小形状改变构件（20a; 7）的长度 ; 7a; 9）。 所述延迟装置（21a; 8; 8a; 10）在所述延迟装置再吸收时从其第一配置移动到其第二配置。

公开(公告)号：EP2181669A3

公开(公告)日：2011-11-23

申请号：EP10154122.5

申请日：2002-12-20

申请人： Edwards Lifesciences AG

发明人： Solem, Jan Otto ,  Kimblad, Per-Ola ,  Von Oepen, Randolf ,  Seibold, Gerd ,  Michlitsch, Kenneth ,  Ha, Suk-Woo ,  Eckert, Karl-Ludwig

IPC分类号： A61F2/24

CPC分类号： A61F2/2451 ,  A61F2/07 ,  A61F2/2481 ,  A61F2/26 ,  A61F2002/043 ,  A61F2002/072 ,  A61F2002/826 ,  A61F2002/828 ,  A61F2002/8483 ,  A61F2210/0004

摘要： Device for treating mitral insufficiency and a method for producing the device. The device comprises a proximal stent section (222); a distal stent section (224); a central stent section (226) interconnecting said proximal stent section (222) and said distal stent section (226); and at least one biodegradable structure (228), disposed on the central stent section (226). Said proximal stent section (222) and said distal stent section (226) being radially expandable by deployment of said device. Moreover said biodegradable structure (228) is arranged to retain the central section (226) in a contracted shape for a predetermined period after deployment of the device.

公开(公告)号：EP2181670A3

公开(公告)日：2011-05-25

申请号：EP10154124.1

申请日：2002-12-20

申请人： Edwards Lifesciences AG

发明人： Solem, Jan Otto ,  Kimblad, Per-Ola ,  Von Oepen, Randolf ,  Seibold, Gerd ,  Michlitsch, Kenneth ,  Ha, Suk-Woo ,  Eckert, Karl-Ludwig

IPC分类号： A61F2/24 ,  A61F2/84

CPC分类号： A61F2/2451 ,  A61F2/07 ,  A61F2/2481 ,  A61F2/26 ,  A61F2002/043 ,  A61F2002/072 ,  A61F2002/826 ,  A61F2002/828 ,  A61F2002/8483 ,  A61F2210/0004

摘要： A device for reshaping a mitral valve annulus (25), said device being elongate and having such dimensions as to be insertable into a coronary sinus (24). The device comprises fixing means (22, 23; 22a, 23a) for fixing the ends of the device within the coronary sinus (24); anda shape changing member (20a; 7; 7a; 9) extending between the fixing means (22, 23; 22a, 23a). The shape changing member (20a; 7; 7a; 9) includes a plurality of adjacent structural cells. The device includes resorbable delay means (21 a; 8; 8a; 10) that in a first configuration retrains at least two of said plurality of adjacent structural elements in a first, relatively elongate state of shape (K; D; E) and wherein the delay means in a second configuration releases said at least two adjacent structural elements to assume a second, relatively shortened state of shape (K'; D'; E'), thereby reducing a length of the shape-changing member (20a; 7; 7a; 9). The delay means (21 a; 8; 8a; 10) moves from its first configuration to its second configuration upon resorbtion of the delay means.

公开(公告)号：EP2181668A1

公开(公告)日：2010-05-05

申请号：EP10154120.9

申请日：2002-12-20

申请人： Edwards Lifesciences AG

发明人： Solem, Jan Otto ,  Kimblad, Per-Ola ,  Von Oepen, Randolf ,  Seibold, Gerd ,  Michlitsch, Kenneth ,  Ha, Suk-Woo ,  Eckert, Karl-Ludwig

IPC分类号： A61F2/24 ,  A61F2/84

CPC分类号： A61F2/2451 ,  A61F2/07 ,  A61F2/2481 ,  A61F2/26 ,  A61F2002/043 ,  A61F2002/072 ,  A61F2002/826 ,  A61F2002/828 ,  A61F2002/8483 ,  A61F2210/0004

摘要： Device for treating mitral annulus dilatation. The device comprises a balloon catheter (214) having proximal and distal ends; a lumen (213) extending therethrough; and a balloon (215); the balloon catheter (214) having contracted and deployed states, wherein the balloon (215) comprises a predetermined shape in the deployed state; and a stent (212) having contracted and deployed states, wherein the stent (212) is plastically deformable by the balloon catheter (214) and substantially conforms to the predetermined shape of the balloon (215) in the deployed state of the balloon catheter (214), wherein the stent (212) is configured to apply a compressive load on the mitral valve annulus in the deployed state.

摘要翻译： 二尖瓣环扩张装置。 该装置包括具有近端和远端的球囊导管（214） 延伸穿过其中的内腔（213）; 和气球（215）; 所述气囊导管（214）具有收缩和展开状态，其中所述球囊（215）在展开状态下包括预定形状; 以及具有收缩和展开状态的支架（212），其中所述支架（212）在气囊导管（21）的展开状态下可通过气囊导管（214）塑性变形并且基本上符合气囊（215）的预定形状， 214），其中支架（212）构造成在展开状态下在二尖瓣环上施加压缩负载。