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公开(公告)号：EP4157336A1
公开(公告)日：2023-04-05
申请号：EP21729863.7
申请日：2021-05-28
申请人： Fundació Privada Institut d'Investigació Oncològica de Vall-Hebron , Institució Catalana de Recerca i Estudis Avançats
发明人： ARRIBAS LÓPEZ, Joaquín , RIUS RUIZ, Irene , ROMÁN ALONSO, Macarena , GROS VIDAL, Alena , FAJARDO CALDERÓN, Carlos Alberto , KLEIN, Christian , MOESSNER, Ekkehard
IPC分类号： A61K39/00 , A61P35/00 , C07K14/725 , C07K14/705 , C07K16/32
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72.发明公开
公开(公告)号：EP4074319A1
公开(公告)日：2022-10-19
申请号：EP21382320.6
申请日：2021-04-15
申请人： Fundació Hospital Universitari Vall d'Hebron - Institut de Recerca , Fundació Institut Català de Nanociència i Nanotecnologia (ICN2) , Institució Catalana de Recerca I Estudis Avançats
发明人： FRANCO PUNTES, Víctor , CASALS MERCADAL, Eudald , ZAPATA VICTORI, Miguel Angel , SALAS TORRAS, Anna , DUARRI PIQUÉ, Anna , BADIA PÉREZ, Anna , GARCÍA ARUMÍ, Josep
IPC分类号： A61K33/244 , A61K9/00 , A61P27/00 , A61P27/06 , A61P35/00
摘要： Present invention relates to colloidal suspension of single crystal cerium oxide nanoparticles for use in the treatment of a disorder or disease of the posterior segment of the eye, said treatment comprising administration of a topical ophthalmic dose of the colloidal suspension. Invention also includes particular new eye drop suspensions.
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公开(公告)号：EP4007637A1
公开(公告)日：2022-06-08
申请号：EP20750250.1
申请日：2020-07-31
申请人： Fundació Hospital Universitari Vall d'Hebron - Institut de Recerca , Fundació Institut Català de Nanociència i Nanotecnologia (ICN2) , Institució Catalana de Recerca I Estudis Avançats
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公开(公告)号：EP3964828A1
公开(公告)日：2022-03-09
申请号：EP20194360.2
申请日：2020-09-03
申请人： Université de Genève , Consejo Superior de Investigaciones Cientificas , Institució Catalana de Recerca I Estudis Avançats
IPC分类号： G01N27/403 , G01N27/416
摘要： The present invention relates to a sensor device for measuring a value comprising a reference electrode and an indicator electrode, the measure of said parameter being based on an electrical energy transferred between the sample electrode and the reference electrode, a conductor for transferring the electrical energy between the reference electrode and the sample electrode, and an ionic bridge.
The sensor device further comprises a storage module for storing the electrical energy transferred between the reference electrode and the sample electrode, and isolating means configured for isolating the storage module from the conductor, the measure of the parameter of the analyte being derived from the stored electrical energy.
The invention further relates to an apparatus based on the storage module of said sensor device, a system comprising said sensor device and a method using said sensor device.-
75.发明公开
公开(公告)号：EP3832381A1
公开(公告)日：2021-06-09
申请号：EP19383089.0
申请日：2019-12-05
发明人： KOPPENS, Frank , TERRÉS, Bernat , AGARWAL, Hitesh
IPC分类号： G02F1/025
摘要： The present invention relates to an electro-optical modulator, particularly to a double layer graphene modulator having an optimized arrangement to provide both a large optical bandwidth and a high optical transmission for light travelling through an optical waveguide (W) of the modulator, wherein at least one of a top (Gu) and a bottom (Gb) graphene sheets extends along a X-direction:
- above part of the width of the optical waveguide (W), wherein said part ranges from 50% to 100% of the width of the optical waveguide (W); or
- completely above the whole width of the optical waveguide (W), and beyond through a respective further projecting portion with a length, along the X direction, of up to 25% of the optical waveguide (W) width.
The present invention also relates to a method for obtaining the electro-optical modulator of the invention.-
公开(公告)号：EP3798612A1
公开(公告)日：2021-03-31
申请号：EP18768924.5
申请日：2018-05-23
申请人： Fundació Institut de Ciències Fotòniques , Institució Catalana De Recerca I Estudis Avançats (ICREA)
IPC分类号： G01N21/45 , G01N21/552
摘要： The invention relates to an apparatus for probing a sample (4) comprising a light source (1) for emitting an illuminating light beam, a birefringent element (3) for splitting the illuminating light beam into two sheared beams, a reflective element (6) for reflecting the two sheared beams, wherein the apparatus is configured such that the reflected beams propagate through the birefringent element (3) for recombining the reflected beams, and a detector (7) for detecting the recombined beam, wherein the sample (4) is arrangeable in the optical path of the sheared beams or at the backside of a reflective surface in the optical path of the sheared beams, the reflective surface exhibiting a surface plasmon resonance or a localized surface plasmon resonance.
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公开(公告)号：EP3793730A1
公开(公告)日：2021-03-24
申请号：EP19724418.9
申请日：2019-05-13
申请人： Consejo Superior de Investigaciones Cientificas , Institució Catalana De Recerca I Estudis Avançats (ICREA) , Fuelium, SL
发明人： ESQUIVEL BOJORQUEZ, Juan Pablo , SABATÉ VIZCARRA, Maria de les Neus , CASTELLARNAU AYMAR, Marc , GASSÓ PONS, Sergi
IPC分类号： B01L3/00 , G01N33/558 , G01N33/543
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公开(公告)号：EP3719557A1
公开(公告)日：2020-10-07
申请号：EP17840589.0
申请日：2017-11-30
摘要： The invention relates to an optical endoscope (1) comprising an optical fiber element (2) with a proximal end (3) and a distal end (4), wherein an optical waveguide block (6) is arranged at the distal end (4) of the optical fiber element (2), the optical waveguide block (6) comprising a rigid material with two or more optical waveguides (7) formed therein.
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公开(公告)号：EP3712128A1
公开(公告)日：2020-09-23
申请号：EP19382189.9
申请日：2019-03-18
申请人： Fundació Institut Català d'Investigació Química (ICIQ) , Institució Catalana de Recerca i Estudis Avançats (ICREA)
IPC分类号： C07D207/34 , C07C303/40 , C07D209/88
摘要： Problem: The present invention solves the problem of providing an alternative metal-free method for intermolecular amination of C-H bonds applicable to a broad range of substrates, wherein the substrate is essentially in stoichiometric amounts with respect to the amination reagent.
Solution: The present invention relates to a photochemical method for the intermolecular coupling of an amination agent with a compound comprising a fragment of formula -C a -H, said method converting the fragment of formula - C a -H in a fragment of formula -C a -NSO 2 R 1 , and comprising the step of contacting under light irradiation and in an aprotic solvent an amination agent with a compound comprising a fragment of formula -C a -H in the presence of a compound of formula (I)
Arl(O 2 CR 3 ) 2 (I)
and a catalytically effective amount of iodine wherein the amination agent is selected from the compounds of formula R 1 SO 2 NHR 2 and the compounds of formula R 1 SO 2 N=IR 2 '.-
公开(公告)号：EP3683845A1
公开(公告)日：2020-07-22
申请号：EP19382025.5
申请日：2019-01-16
IPC分类号： H01L29/78 , H01L31/10 , H01L29/16 , C01B32/182
摘要： The present invention relates to an electronic device, comprising:
- a GFET;
- noise suppression means comprising:
- a modulation unit applying to a gate (G) of the GFET a signal V g with frequency f m to modulate charge carrier density of a graphene channel around the charge neutrality point between charge carrier density values at frequency f m ,
- a control unit (CU), and
- a demodulation circuit which is CMOS-implemented and that:
- comprises first and second circuital branches alternately switchable to demodulate an electrical signal of frequency f m ; or
- is configured to generate and apply a signal V b with frequency f mb to a source (S) of the GFET continuously, simultaneously and with a delay t d to induce a phase with respect to V g to yield a maximal demodulated output signal (So).
The present invention also concerns to a method for suppressing noise for the device of the invention.
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