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77 条记录 (耗时 0.017 秒)

    USE OF GLUCOCORTICOID RECEPTOR-SPECIFIC ANTAGONISTS FOR THE TREATMENT OF DELIRIUM
    71.
    发明授权
    USE OF GLUCOCORTICOID RECEPTOR-SPECIFIC ANTAGONISTS FOR THE TREATMENT OF DELIRIUM 有权
    糖皮质激素受体特异性拮抗剂的谵妄治疗中的应用

    公开(公告)号：EP1390037B1

    公开(公告)日：2010-12-22

    申请号：EP02731689.2

    申请日：2002-05-06

    申请人： Corcept Therapeutics, Inc.

    发明人： BELANOFF, Joseph, K.

    IPC分类号： A61K31/56 ,  A61P5/46 ,  A61P25/00

    CPC分类号： A61K31/56

    摘要： This invention generally pertains to the field of psychiatry. In particular, this invention pertains to the discovery that agents which inhibit the binding of cortisol to its receptors can be used in methods for treating delirium. Mifepristone, a potent specific glucocorticoid receptor antagonist, can be used in these methods. The invention also provides a kit for treating delirium in a human including a glucocorticoid receptor antagonist and instructional material teaching the indications, dosage and schedule of administration of the glucocorticoid receptor antagonist.

    METHODS FOR PREVENTING ANTIPSYCHOTIC-INDUCED WEIGHT GAIN
    76.
    发明公开
    METHODS FOR PREVENTING ANTIPSYCHOTIC-INDUCED WEIGHT GAIN 有权
    用于预防体重增加方法抗精神病药的一个结果

    公开(公告)号：EP1408981A1

    公开(公告)日：2004-04-21

    申请号：EP02750269.9

    申请日：2002-07-22

    申请人： Corcept Therapeutics, Inc.

    发明人： BELANOFF, Joseph, K. ,  SCHATZBERG, Alan, F.

    IPC分类号： A61K31/56

    CPC分类号： A61K45/06 ,  A61K31/00 ,  A61K31/5513 ,  A61K31/567 ,  A61K31/575 ,  A61K2300/00

    摘要： This invention generally pertains to the field of psychiatry. In particular, this invention pertains to the discovery that agents capable of inhibiting the binding of cortisol to its receptors can be used in methods for preventing antipsychotic-induced weight gain. Mifepristone, a potent specific glucocorticoid receptor antagonist, can be used in these methods. The invention also provides a kit for preventing AP-induced weight gain in a human including a glucocorticoid receptor antagonist and instructional material teaching the indications, dosage and schedule of administration of the glucocorticoid receptor antagonist.

    METHODS FOR TREATING STRESS DISORDERS USING GLUCOCORTICOID RECEPTOR-SPECIFIC ANTAGONISTS
    77.
    发明公开
    METHODS FOR TREATING STRESS DISORDERS USING GLUCOCORTICOID RECEPTOR-SPECIFIC ANTAGONISTS 有权
    法与压力有关的疾病的治疗中使用糖皮质激素REZEPTO特异性拮抗剂

    公开(公告)号：EP1370268A2

    公开(公告)日：2003-12-17

    申请号：EP02725270.9

    申请日：2002-03-19

    申请人： Corcept Therapeutics, Inc.

    发明人： BELANOFF, Joseph, K.

    IPC分类号： A61K31/59 ,  A61K31/56

    CPC分类号： A61K31/59 ,  A61K31/56 ,  A61K31/57

    摘要： This invention generally pertains to the field of psychiatry. In particular, this invention pertains to the discovery that agents which inhibit the binding of cortisol to its receptors can be used in methods for treating stress disorders. Mifepristone, a potent specific glucocorticoid receptor antagonist, can be used in these methods. The invention also provides a kit for treating stress disorders in a human including a glucocorticoid receptor antagonist and instructional material teaching the indications, dosage and schedule of administration of the glucocorticoid receptor antagonist.