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公开(公告)号：EP2338907A1
公开(公告)日：2011-06-29
申请号：EP10014673.7
申请日：2008-07-25
发明人： Singh, Harpreet , Schoor, Oliver , Trautwein, Claudia , Hilf, Norbert , Weinschenk, Toni , Walter, Steffen , Lewandrowski, Peter
CPC分类号： A61K39/0011 , A61K35/17 , A61K2039/5158 , A61K2039/572 , C07K7/06 , C07K7/08 , C07K14/47 , C07K14/4748 , C07K14/495 , C07K14/7051 , C07K16/40 , C07K19/00 , C07K2317/34 , C07K2319/00 , C12N5/0638 , C12N9/0036 , C12N9/13 , C12N2502/1157 , C12Y208/02011
摘要： The present invention relates to amino acid sequences of peptides derived from tumour associated antigens that are able to bind to MHC complexes of either class, and elicit an immune response, as well as to uses of said peptides for the treatment of diseases.
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公开(公告)号：EP1734048B1
公开(公告)日：2008-12-17
申请号：EP06015805.2
申请日：2003-03-27
CPC分类号： C07K7/06 , A61K38/00 , A61K48/00 , A61K2039/5158 , C07K14/4748 , G01N33/505 , G01N33/56977 , G01N33/574 , Y10S530/828
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公开(公告)号：EP1734049B1
公开(公告)日：2008-12-03
申请号：EP06015806.0
申请日：2003-03-27
CPC分类号： C07K7/06 , A61K38/00 , A61K48/00 , A61K2039/5158 , C07K14/4748 , G01N33/505 , G01N33/56977 , G01N33/574 , Y10S530/828
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84.发明公开Immunogenic T-helper epitopes from human tumour antigens and immunotherapeutic methods using said epitopes 有权免疫原T-Helfer表位免疫疗法免疫治疗方法
公开(公告)号：EP1642905A1
公开(公告)日：2006-04-05
申请号：EP04023546.7
申请日：2004-10-02
IPC分类号： C07K14/47 , A61K39/00 , G01N33/574 , C12N15/62 , C12N15/00
CPC分类号： C07K14/4748
摘要： The present invention relates to immunotherapeutic methods, and molecules and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer, in particular renal cancer. The present invention furthermore relates to tumour-associated T-helper cell peptide epitopes, alone or in combination with other tumour-associated peptides, that serve as active pharmaceutical ingredients of vaccine compositions which stimulate anti-tumour immune responses. In particular, the present invention relates to 338 novel peptide sequences derived from HLA class II molecules of human tumour cell lines which can be used in vaccine compositions for eliciting anti-tumour immune responses.
摘要翻译： 本发明涉及免疫治疗方法，以及用于免疫治疗方法的分子和细胞。 特别地，本发明涉及癌症，特别是肾癌的免疫治疗。 本发明还涉及用作刺激抗肿瘤免疫应答的疫苗组合物的活性药物成分的单独或与其它肿瘤相关肽组合的肿瘤相关T辅助细胞肽表位。 特别地，本发明涉及可用于引发抗肿瘤免疫应答的疫苗组合物中的338种来自人类肿瘤细胞系HLA II类分子的新型肽序列。
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