SLURRY DISPENSER FOR RADIOISOTOPE PRODUCTION
    84.
    发明公开
    SLURRY DISPENSER FOR RADIOISOTOPE PRODUCTION 有权
    SUSPENSIONSDISPENSER FOR放射性同位素生产

    公开(公告)号:EP2593943A1

    公开(公告)日:2013-05-22

    申请号:EP11749024.3

    申请日:2011-07-07

    申请人: Mallinckrodt LLC

    IPC分类号: G21G1/00 B01F5/10 B01F9/02

    摘要: A slurry dispensing system (10) is disclosed. A peristaltic pump (28) may direct a flow of slurry out of a horizontal mixer (20) to a slurry dispenser (140). This slurry dispenser (140) may be operated on a programmed manner by a controller (260) to dispense slurry into a container (36). Both a bypass valve (172) and a dispensing valve (204) of the slurry dispenser may be opened/closed on a programmed basis by the controller (260) to deliver slurry to a container (36), such as a glass column. Slurry may be intermittently directed into a metering chamber (194) of the slurry dispenser (140), while the remainder of the slurry being directed into the slurry dispenser (140) may be recirculated back to the horizontal mixer (20).

    ISOTOPE PREPARATION METHOD
    85.
    发明公开
    ISOTOPE PREPARATION METHOD 有权
    用于生产ISOTOP

    公开(公告)号:EP2564396A1

    公开(公告)日:2013-03-06

    申请号:EP11719186.6

    申请日:2011-04-29

    申请人: Algeta ASA

    IPC分类号: G21G1/00 A61K51/02

    摘要: The present invention provides a method for the generation of
    223 Ra of pharmaceutically tolerable purity comprising i) preparing a generator mixture comprising
    227 Ac,
    227 Th and
    223 Ra; ii) loading said generator mixture onto a strong base anion exchange resin; iii) eluting said
    223 Ra from said strong base anion exchange resin using a first mineral acid in an alcoholic aqueous solution to give a first eluted
    223 Ra solution; iv) loading the
    223 Ra of the first eluted
    223 Ra solution onto a strong acid cation exchange resin; and v) eluting the
    223 Ra from said strong acid cation exchange resin using a second mineral acid in aqueous solution to provide a second eluted solution. The invention additionally provides products of corresponding purity and/or products obtained or obtainable by such a method.

    RADIONUCLIDE GENERATOR AND METHOD OF STERILIZATION
    88.
    发明公开
    RADIONUCLIDE GENERATOR AND METHOD OF STERILIZATION 有权
    放射性核素和灭菌过程

    公开(公告)号:EP2430636A1

    公开(公告)日:2012-03-21

    申请号:EP09844726.1

    申请日:2009-05-13

    IPC分类号: G21G1/00 G21H5/00

    摘要: A column assembly of a radionuclide generator includes a column that retains a parent radionuclide that spontaneously decays to a relatively short-lived daughter radionuclide. A fluid path extends from an inlet port to the column and then to an outlet port and allows daughter radionuclide to be eluted from the radionuclide generator for use. Improved retention of parent radionuclide in the column is accomplished by preventing fluid from entering the flow path in a liquid state, such as during sterilization. Proper column chemistry is also promoted by preventing excess moisture from coalescing in the column, which may promote a higher and/or more reliable yield of daughter radionuclide from a radionuclide generator.

    Column geometry to maximize elution efficiencies for molybdenum-99
    89.
    发明公开
    Column geometry to maximize elution efficiencies for molybdenum-99 有权
    99年以上的Säulengeometriezur Maximierung der ElutionseffizienzenfürMolybdän-99

    公开(公告)号:EP2375421A2

    公开(公告)日:2011-10-12

    申请号:EP11161361.8

    申请日:2011-04-06

    IPC分类号: G21G1/00

    摘要: At least one system (100) for eluting a radioactive material and a method of eluting a radioactive material is provided. The system for eluting a radioactive material may include an elution column (105) configured to enclose an radioactive material, a first sealing member sealing a first end of the elution column, a second sealing member sealing a second end of the elution column, an elution supply source (20) connected to the first end of the elution column via a first needle (22), a collection system (40) connected to the second end of the elution column via a second needle (42), and a filter (150) in the elution column, the filter being configured to support the radioactive material and prevent the radioactive material from contacting the second needle.

    摘要翻译: 提供至少一种用于洗脱放射性物质的系统(100)和放射性物质的洗脱方法。 用于洗脱放射性物质的系统可以包括构造成包围放射性物质的洗脱塔(105),密封洗脱塔的第一端的第一密封构件,密封洗脱塔的第二端的第二密封构件,洗脱塔的第二端 经由第一针(22)连接到洗脱塔的第一端的供应源(20),经由第二针(42)连接到洗脱塔的第二端的收集系统(40)和过滤器(150) ),过滤器被配置为支撑放射性物质并防止放射性物质接触第二针。