公开(公告)号：EP1519928B1

公开(公告)日：2014-04-30

申请号：EP03738072.2

申请日：2003-06-20

申请人： MAKHTESHIM CHEMICAL WORKS LIMITED

发明人： STRAUB, Alexander

IPC分类号： C07D277/36

CPC分类号： C07D277/36

公开(公告)号：EP2258194A2

公开(公告)日：2010-12-08

申请号：EP10178570.7

申请日：2005-10-31

申请人： MAKHTESHIM CHEMICAL WORKS LIMITED

发明人： Barazani, Avner ,  Barkai, Jacob

IPC分类号： A01N51/00 ,  A01N47/02 ,  A01N43/90

CPC分类号： A01N47/34 ,  A01N43/90 ,  A01N47/02 ,  A01N51/00 ,  A01N2300/00

摘要： The present invention provides an insecticidal composition comprising of at least one insecticidal compound with effective knock-down action selected from among group (A) comprising of imidacloprid, acetamiprid, thiamethoxam, thiacloprid, nitenpyram, dinotefuran, clothianidin, abamectin, emamectin, emamectin benzoate and fipronil, and at least one insecticidal compound with effective long-term action selected from among group (B) of insect growth regulators comprising of benzoylphenyl urea (BPU) compounds selected from among novaluron, lufenuron, hexaflumuron, triflumuron, diflubenzuron, chlorfluazuron, flufenoxuron, noviflumuron and teflubenzuron. Optionally, said insecticidal composition may further contain excipients and/or additives and/or surface active agents. Further provided is a method for insect control, comprising of applying at least one insecticidal compound with effective knock-down action selected from among group (A) comprising of imidacloprid, acetamiprid, thiamethoxam, thiacloprid, nitenpyram, dinotefuran, clothianidin, abamectin, emamectin, emamectin benzoate and fipronil, and at least one insecticidal compound with effective long-term action selected from among group (B) of insect growth regulators (IGR) comprising of benzoylphenyl urea (BPU) compounds; to a crop, agricultural product, plant matter, animal or locale.

摘要翻译： 本发明提供一种杀虫组合物，其包含至少一种具有有效击倒作用的杀虫化合物，该杀虫化合物选自吡虫啉，啶虫脒，噻虫嗪，噻虫啉，烯尼龙嘧啶，二氢呋喃，噻虫胺，阿维菌素，艾玛凝胶，伊马替丁苯甲酸酯和 氟虫腈和至少一种具有有效长效作用的杀虫化合物，其选自组合（B）昆虫生长调节剂，其包含选自诺瓦脲，lu脲脲，氟苯脲，三氟龙，除虫脲，氯氟脲，氟草酮， noviflumuron和teflubenzuron。 任选地，所述杀虫组合物还可含有赋形剂和/或添加剂和/或表面活性剂。 进一步提供一种昆虫防治方法，其特征在于，包括施用至少一种杀虫化合物，所述杀虫化合物具有选自由吡虫啉，啶虫脒，噻虫嗪，噻虫啉，硝苯吡啶，二硝基呋喃，噻虫胺，阿维菌素，伊玛菌素组成的组（A） 甲磺草酮苯甲酸酯和氟虫腈，以及至少一种具有有效长效作用的杀虫化合物，其选自包含苯甲酰基苯基脲（BPU）化合物的昆虫生长调节剂（IGR）组（B）; 作物，农产品，植物物质，动物或地方。

公开(公告)号：EP2102174A1

公开(公告)日：2009-09-23

申请号：EP07849577.7

申请日：2007-12-16

申请人： MAKHTESHIM CHEMICAL WORKS LIMITED

发明人： OVADIA, David ,  STURKOVICH, Raya ,  LEONOV, David

IPC分类号： C07D239/54

CPC分类号： C07D239/52 ,  C07D239/54

摘要： The present invention provides a process for reacting between a phenol derivative and an aromatic substrate under phenolate forming conditions comprising the following steps: (a) reacting a phenol derivative with a base in a polar organic solvent to obtain a phenolate salt, wherein water is removed from the reaction mixture during the reaction. (b) adding the aromatic substrate to the reaction mixture obtained in step (a), (c) heating the reaction mixture of step (b) to a temperature in the range of 80° to 1300C, preferebly, 90- 1000C for 2 to 7 hours to obtain a phenoxy substituted aromatic substrate, (d) removing the solvent from the mixture of step (c) and further isolating and purifying the phenoxy substituted aromatic substrate. Optionally, the removal of water during step (a) is in conjunction with partial removal of the organic solvent.

摘要翻译： 本发明提供了一种在苯酚盐形成条件下在苯酚衍生物和芳族底物之间反应的方法，该方法包括以下步骤：（a）使苯酚衍生物与碱在极性有机溶剂中反应以获得酚盐，其中除去水 从反应混合物中反应。 （b）将芳族底物加入到步骤（a）中获得的反应混合物中，（c）将步骤（b）的反应混合物加热至80-130℃的温度，优选90-110℃加热2至 7小时以获得苯氧基取代的芳族底物，（d）从步骤（c）的混合物中除去溶剂并进一步分离和纯化苯氧基取代的芳族底物。 任选地，在步骤（a）期间除去水与部分除去有机溶剂结合。

公开(公告)号：EP2061311A2

公开(公告)日：2009-05-27

申请号：EP07805596.9

申请日：2007-09-16

申请人： Yissum Research Development Company of the Hebrew University of Jerusalem ,  MAKHTESHIM CHEMICAL WORKS LIMITED

发明人： MAGDASSI, Shlomo ,  DAYAN, Benny ,  LEVI-RUSO, Ganit

IPC分类号： A01N25/28

CPC分类号： A01N25/14 ,  A01N25/04 ,  A01N47/34 ,  A01N53/00

摘要： The present invention provides a redispersible powder and aqueous dispersions of nanoparticles of water insoluble organic pesticides. The invention further provides methods for preparing the redispersible powder and the aqueous dispersion, wherein the methods include preparation of an oil-in-water nanoemulsion or microemulsion and solvent removal. The present invention also provides pesticidal compositions of the redispersible powder or aqueous dispersions, and their agricultural use in combating pests.

公开(公告)号：EP1899312A2

公开(公告)日：2008-03-19

申请号：EP06745168.2

申请日：2006-06-22

申请人： MAKHTESHIM CHEMICAL WORKS LIMITED

发明人： LEONOV, David ,  OVADIA, David ,  STURKOVICH, Raya

IPC分类号： C07D301/18

CPC分类号： C07D301/18 ,  C07D303/08

摘要： The present invention provides a process for the preparation of l-halomethyl-2-phenyl-l-phenyl oxirane, wherein the phenyl substituents may be mono-, di- or poly- halo substituted, wherein 3 -halo- 2 -phenyl- 1-phenyl propene is reacted with an anhydride and hydrogen peroxide in a solvent selected from among alkyl esters, followed by subsequent extraction and separation of the organic phase and isolation of the oxirane . The isolation and purification of the oxirane is carried out subsequent to the reaction and includes extraction and crystallization in single, multiple or repeated stages .

公开(公告)号：EP1330160B1

公开(公告)日：2006-08-23

申请号：EP01982691.6

申请日：2001-11-01

申请人： MAKHTESHIM CHEMICAL WORKS LIMITED

发明人： BARAZANI, Avner

IPC分类号： A01N25/34 ,  A01G13/02

CPC分类号： A01G13/0268 ,  A01N25/34 ,  Y10S47/11 ,  Y10S428/907 ,  Y10T428/24942 ,  Y10T428/31725 ,  Y10T428/31728 ,  Y10T428/31786 ,  Y10T428/31855 ,  Y10T428/31913 ,  Y10T428/3192

摘要： A sheet for pest control, wherein said sheet is of polymeric material and comprises at least two layers; a top layer and a bottom layer, wherein the bottom layer contains a herbicide and one or more pesticides selected from among fungicides and insecticides, and the top layer optionally containing an insecticide and/or fungicide. Other aspects of the invention include a polymeric composition used in the preparation of the sheets and a method for pest control in agriculture, horticulture and gardens.

公开(公告)号：EP0403952A3

公开(公告)日：1992-02-12

申请号：EP90111202.9

申请日：1990-06-13

申请人： MAKHTESHIM CHEMICAL WORKS LIMITED

发明人： Sharvit, Joseph ,  Pereferkovich. Abraham Adolf

IPC分类号： C07C217/20 ,  C07C217/16 ,  C07C213/00

CPC分类号： C07C213/02 ,  C07C213/08

摘要： N-n-propyl-N-2-(2,4,6-trichlorophenoxy) ethyl amine is prepared by reacting 2-phenoxy ethanol with thionyl chloride in the presence of a catalytic amount of tetra-alkyl ammonium halide optionally in the presence of a solvent to form 2-phenoxy ethyl chloride; reacting the 2-phenoxy ethyl chloride with n-propylamine at a temp-erature of from 50°C to 150°C optionally in the presence of a solvent to form N-n-propyl-N-2-phenoxy-ethyl amine; selectively chlorinating N-n-propyl-N-2-phenoxyethyl amine with chlorine in the presence of a solvent; and recovering the N-n-propyl-N-2-(2,4,6-trichlorophenoxy) ethyl amine formed.

公开(公告)号：EP0404092A2

公开(公告)日：1990-12-27

申请号：EP90111631.9

申请日：1990-06-20

申请人： MAKHTESHIM CHEMICAL WORKS LIMITED

发明人： Sharvit, Joseph ,  Pereferkovich, Abraham Adolf ,  Shohat, Daniel

IPC分类号： C07C217/20 ,  C07C213/00 ,  C07C43/225 ,  C07C41/18

CPC分类号： C07C213/02 ,  C07C41/22 ,  C07C43/23 ,  C07C43/225

摘要： N-n-propyl-N-2-(2,4,6-trichlorophenoxy)-ethylamine is prepared by selectively chlorinating 2-phenoxy ethanol by reacting it with chlorine either in the presence of hydrogen chloride at a temperature of from -10°C to 50°C or in the presence of urea at a temperature of from 20°C to 55°C in a water/carbon tetrachloride solvent mixture to form 2-(2,4,6-tri­chlorophenoxy)ethanol; reacting the 2-(2,4,6-trichloro­phenoxy)ethanol with thionyl chloride in the presence of a catalytic amount of tetraalkyl ammonium chloride, optionally in the presence of a solvent to form 2-(2,4,6-trichlorophenoxy,ethyl chloride; and reacting the 2-(2,4,6-trichlorophenoxy) ethyl chloride with n-propylamine at a temperature of from 20°C to 150°C, optionally in the presence of water to form N-n-propyl-­N-2-(2,4,6-trichlorophenoxy) ethyl amine,

摘要翻译： 通过使2-苯氧基乙醇与氯反应，在氯化氢的存在下，在-10℃至-10℃的温度下，通过与氯反应来选择性地制备N-丙基-N-2-（2,4,6-三氯苯氧基） - 乙胺 50℃或在尿素存在下，在20℃至55℃的温度下，在水/四氯化碳溶剂混合物中形成2-（2,4,6-三氯苯氧基）乙醇; 任选在溶剂存在下，在催化量的四烷基氯化铵存在下使2-（2,4,6-三氯苯氧基）乙醇与亚硫酰氯反应，形成2-（2,4,6-三氯苯氧基）乙基 氯化物;以及2-（2,4,6-三氯苯氧基）乙基氯与正丙胺的反应温度为20℃至150℃，任选在水存在下反应形成N-丙基-N-2 - （2,4,6-三氯苯氧基）乙胺，

公开(公告)号：EP0254049A3

公开(公告)日：1989-04-12

申请号：EP87108960.3

申请日：1987-06-23

申请人： MAKHTESHIM CHEMICAL WORKS LIMITED

发明人： Bracha, Peretz ,  Korat, Moshe

IPC分类号： A01N43/54 ,  A01N47/04 ,  C07D239/95

CPC分类号： C07D239/95 ,  A01N43/54 ,  A01N47/04 ,  C07D239/96

摘要： Herbicidal compositions containing a compound of the formula: wherein
R is hydrogen, a lower alkyl, lower alkoxy, amino, substituted amino, cycloalkyl, halogen, or nitro;
Rʹ is selected from the group consisting of a haloalkylthio group containing l or 2 carbon atoms and at least two halogen sub­stituents; linear or branched alkyl and alkenyl group having from 2 to l0 carbon atoms, optionally substituted by halogen, hydroxy, lower alkoxy or haloalkyl; and cycloalkyl of 5 to l0 carbon atoms, optionally substituted by halogen, hydroxy, lower alkoxy, or haloalkyl; provided that at least one of Rʹ is a haloalkylthio group as defined;
n is zero or an integer from l to 4; and
X is oxygen or sulfur

公开(公告)号：EP0254049A2

公开(公告)日：1988-01-27

申请号：EP87108960.3

申请日：1987-06-23

申请人： MAKHTESHIM CHEMICAL WORKS LIMITED

发明人： Bracha, Peretz ,  Korat, Moshe

IPC分类号： A01N43/54 ,  A01N47/04 ,  C07D239/95

CPC分类号： C07D239/95 ,  A01N43/54 ,  A01N47/04 ,  C07D239/96

摘要： Herbicidal compositions containing a compound of the formula: wherein
R is hydrogen, a lower alkyl, lower alkoxy, amino, substituted amino, cycloalkyl, halogen, or nitro;

Rʹ is selected from the group consisting of a haloalkylthio group containing l or 2 carbon atoms and at least two halogen sub­stituents; linear or branched alkyl and alkenyl group having from 2 to l0 carbon atoms, optionally substituted by halogen, hydroxy, lower alkoxy or haloalkyl; and cycloalkyl of 5 to l0 carbon atoms, optionally substituted by halogen, hydroxy, lower alkoxy, or haloalkyl; provided that at least one of Rʹ is a haloalkylthio group as defined;

n is zero or an integer from l to 4; and

X is oxygen or sulfur

摘要翻译： 含有下式化合物的除草组合物：其中R为氢，低级烷基，低级烷氧基，氨基，取代氨基，环烷基，卤素或硝基; R'选自含有1或2个碳原子的卤代烷硫基和至少两个卤素取代基; 具有2至10个碳原子的直链或支链烷基和烯基，任选被卤素，羟基，低级烷氧基或卤代烷基取代; 5至10个碳原子的环烷基，任选被卤素，羟基，低级烷氧基或卤代烷基取代; 条件是R'中的至少一个是如所定义的卤代烷硫基; n为0或1至4的整数; X为氧或硫