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公开(公告)号：EP3563845B1
公开(公告)日：2023-03-22
申请号：EP17885808.0
申请日：2017-12-28
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公开(公告)号：EP2752190B1
公开(公告)日：2021-03-03
申请号：EP12827070.9
申请日：2012-08-29
发明人： TANAKA, Keiichi
IPC分类号： A61K31/352 , A61P1/16 , C07D311/22 , A61P37/06 , A61P29/00 , A61P19/02 , A61K45/06 , A61K31/573 , A61K31/519 , A61K9/20 , A61P37/00 , A61P37/02 , A61P37/08 , A61P39/00 , A61P43/00
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公开(公告)号：EP3327004B1
公开(公告)日：2020-11-04
申请号：EP16827761.4
申请日：2016-07-15
发明人： TANAKA Tadashi , FUJINO Masataka , FURUYA Kentaro
IPC分类号： C07D215/38 , A61K31/444 , A61K31/4704 , A61K31/4709
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公开(公告)号：EP3636262A1
公开(公告)日：2020-04-15
申请号：EP18810759.3
申请日：2018-06-01
IPC分类号： A61K31/397 , A61P25/28
摘要： An object of the present invention is to provide a drug which prevents progress of Alzheimer's disease and a method of preventing progress of Alzheimer's disease. Alzheimer's disease can be effectively prevented or treated by initiating administration of a pharmaceutical composition comprising 1-(3-(2-(1-benzothiophen-5-yl)ethoxy)propyl)azetidin-3-ol or a salt thereof as an active ingredient to a patient within a certain period from clinical diagnosis of Alzheimer's disease.
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公开(公告)号：EP3633609A1
公开(公告)日：2020-04-08
申请号：EP18809549.1
申请日：2018-04-20
发明人： IWAMI, Kazuchika
摘要： An object of the present invention is to provide a dispensing audit support apparatus and a dispensing audit support method with a high collation accuracy robustness. According to a dispensing audit support apparatus according to one aspect of the present invention, since a position, shape and size of a region of interest are set according to a position of a collation-target medicine in a captured image, and a position, shape and size of a master image are set according to the set region of interest, it is possible to avoid or reduce distortion of the medicine shape, blur, inclusion of an end part into the image, and the like due to the position and orientation of the collation-target medicine. Therefore, influence on collation accuracy is small, and it is possible to enhance the robustness of the collation accuracy.
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公开(公告)号：EP3563847A1
公开(公告)日：2019-11-06
申请号：EP17887220.6
申请日：2017-12-28
IPC分类号： A61K31/397 , A61K9/14 , A61K9/20 , A61K47/20 , A61K47/32 , A61K47/38 , A61P25/00 , A61P43/00
摘要： The object of the present invention is to provide a solid pharmaceutical composition in which both the pre-bitter taste and the post-bitter taste of 1-(3-(2-(1-benzothiophen-5-yl)ethoxy)propyl)azetidin-3-ol or a salt thereof are suppressed. The present invention provides a solid pharmaceutical composition comprising 1-(3-(2-(1-benzothiophen-5-yl)ethoxy)propyl)azetidin-3-ol or a salt thereof and a compound having at least one hydrocarbon group having 8 to 18 carbon atoms and a sulfo group or a salt thereof.
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公开(公告)号：EP3456654A1
公开(公告)日：2019-03-20
申请号：EP17795822.0
申请日：2017-03-15
发明人： TSUNO, Katsuhiro
摘要： The present invention addresses the problem of providing a transport container that is highly heat-insulating. The present invention provides a transport container characterized in being provided with: a first container having a first inner wall with a storage space for storing a transported object and a first outer wall provided on the outside of the first inner wall so as to form, with the first inner wall, a vacuum space therebetween; a first lid that is heat-insulating and is for removably sealing a first opening of the first container; a second container having a second inner wall with a space for storing the first container and the first lid and a second outer wall provided on the outside of the second inner wall so as to form, with the second inner wall, a vacuum space therebetween; a second lid that is heat-insulating and is for removably sealing a second opening of the second container; and a heat storage material for surrounding the transported object inside the storage space.
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9.发明公开
公开(公告)号：EP3438088A1
公开(公告)日：2019-02-06
申请号：EP17775419.9
申请日：2017-03-30
发明人： BABA, Yasutaka , NAGATO, Yusuke , KOSEKI, Yu
IPC分类号： C07C239/08 , A61K31/166 , A61P31/04 , A61P43/00
摘要： Crystals of (2S)-2-((4-((4-((1S)-1,2-dihydroxyethyl)phenyl)ethynyl)benzoyl)(methyl)amino)-N-hydroxy-N',2-dimethylmalonamide having diffraction peaks at diffraction angles (2θ) of 3.8 ± 0.2°, 7.7 ± 0.2°, and 10.8 ± 0.2°, etc., or 8.2 ± 0.2°, 12.4 ± 0.2°, and 13.3 ± 0.2°, etc., in powder X-ray diffraction, a production method thereof, and a pharmaceutical composition.
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公开(公告)号：EP2389937B1
公开(公告)日：2018-08-15
申请号：EP11006318.7
申请日：2003-04-03
发明人： Nakada, Yasushi , Nakagawa, Masaya , Ono, Satoshi
IPC分类号： A61K31/381 , A61K31/473 , A61K31/445 , A61K31/397 , A61P25/28
CPC分类号： A61K45/06 , A61K31/122 , A61K31/21 , A61K31/381 , A61K31/397 , A61K31/445 , A61K31/473 , A61K31/55 , A61K2300/00
摘要： An alkyl ether derivative represented by the formula: wherein R , R , R , R , m and n are as defined in the specification, or salts thereof exhibits synergistically improved anti-hypoxic activity when combined with a compound having an acetylcholine esterase inhibitory activity. Therefore, the combination according to the present invention is useful as a method for improving cerebral function. Further, a pharmaceutical composition containing the compound relating to the combination according to the present invention is useful for treatment and prevention of dysfunction of cerebral acetylcholine neurons in the sequelae of cerebrovascular dementia, senile dementia, Alzheimer's disease and ischemic cerebral lesion and in the cerebral apoplexy or the memory impairment caused by selective neuronal death.
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