公开(公告)号：EP2317916B1

公开(公告)日：2023-06-07

申请号：EP09798250.8

申请日：2009-06-23

发明人： GOODWILL, Patrick W. ,  GONOLLY, Steven M.

IPC分类号： A61B5/05 ,  A61K49/18 ,  G01R33/02 ,  G05F1/00

公开(公告)号：EP2317916A2

公开(公告)日：2011-05-11

申请号：EP09798250.8

申请日：2009-06-23

申请人： The Regents Of The University Of California, Berkeley

发明人： GOODWILL, Patrick W. ,  GONOLLY, Steven M.

IPC分类号： A61B5/05 ,  A61K49/18 ,  G01R33/02

CPC分类号： G01N27/72 ,  A61B5/05 ,  A61B5/0515 ,  A61B5/7257 ,  G01R33/00 ,  G01R33/0213 ,  G01R33/10 ,  G01R33/1269 ,  G01R33/1276

摘要： A magnetic particle imaging apparatus includes magnets [106,107] that produce a gradient magnetic field having a field free region (FFR), excitation field electromagnets [102,114] that produce a radiofrequency magnetic field within the field free region, high-Q receiving coils [112] that detect a response of magnetic particles in the field free region to the excitation field. Field translation electromagnets create a homogeneous magnetic field displacing the field-free region through the field of view (FOV) allowing the imaging region to be scanned to optimize scan time, scanning power, amplifier heating, SAR, dB/dt, and/or slew rate. Efficient multi-resolution scanning techniques are also provided. Intermodulated low and radio-frequency excitation signals are processed to produce an image of a distribution of the magnetic nanoparticles within the imaging region. A single composite image is computed using deconvolution of multiple signals at different harmonics.