公开(公告)号：EP2437772B1

公开(公告)日：2017-12-06

申请号：EP10784168.6

申请日：2010-06-04

申请人： 13Therapeutics, Inc.

发明人： MCCOY, Sharon, L. ,  HEFENEIDER, Steven, H.

IPC分类号： A61K38/16 ,  A61K38/02 ,  A61K38/10 ,  C07K14/00 ,  C07K7/08 ,  A61P29/00 ,  A61P17/06 ,  A61P17/00 ,  A61P19/02

CPC分类号： A61K39/285 ,  A61K38/00 ,  C07K7/06 ,  C07K7/08 ,  C07K14/005 ,  C07K14/07 ,  C07K14/47 ,  C07K2319/10 ,  C12N2710/24122

摘要： Peptides for the treatment of inflammation, and therapeutic uses and methods of using the same are disclosed. Peptides including a transducing sequence are effective for inhibiting cytokine activity and TNF-alpha secretion through interaction with toll-like receptors. Experiments are described illustrating the efficacy of the compounds in treating otitis media.

公开(公告)号：EP2437772A4

公开(公告)日：2013-07-10

申请号：EP10784168

申请日：2010-06-04

申请人： 13THERAPEUTICS INC

发明人： MCCOY SHARON L ,  HEFENEIDER STEVEN H

IPC分类号： A61K38/16 ,  A61K38/02 ,  A61K38/10 ,  A61P17/00 ,  A61P17/06 ,  A61P19/02 ,  A61P29/00 ,  C07K7/08 ,  C07K14/00

CPC分类号： A61K39/285 ,  A61K38/00 ,  C07K7/06 ,  C07K7/08 ,  C07K14/005 ,  C07K14/07 ,  C07K14/47 ,  C07K2319/10 ,  C12N2710/24122

摘要： Peptides for the treatment of inflammation, and therapeutic uses and methods of using the same are disclosed. Peptides including a transducing sequence are effective for inhibiting cytokine activity and TNF-alpha secretion through interaction with toll-like receptors. Experiments are described illustrating the efficacy of the compounds in treating otitis media.

公开(公告)号：EP2437772A1

公开(公告)日：2012-04-11

申请号：EP10784168.6

申请日：2010-06-04

申请人： 13therapeutics, Inc.

发明人： MCCOY, Sharon, L. ,  HEFENEIDER, Steven, H.

IPC分类号： A61K38/16 ,  A61K38/02 ,  A61K38/10 ,  C07K14/00 ,  C07K7/08 ,  A61P29/00 ,  A61P17/06 ,  A61P17/00 ,  A61P19/02

CPC分类号： A61K39/285 ,  A61K38/00 ,  C07K7/06 ,  C07K7/08 ,  C07K14/005 ,  C07K14/07 ,  C07K14/47 ,  C07K2319/10 ,  C12N2710/24122

摘要： Peptides for the treatment of inflammation, and therapeutic uses and methods of using the same are disclosed. Peptides including a transducing sequence are effective for inhibiting cytokine activity and TNF-alpha secretion through interaction with toll-like receptors. Experiments are described illustrating the efficacy of the compounds in treating otitis media.