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    RISK DETERMINATION OF CORONARY ARTERY DISEASE
    1.
    发明公开
    RISK DETERMINATION OF CORONARY ARTERY DISEASE 审中-公开

    公开(公告)号：EP3476299A1

    公开(公告)日：2019-05-01

    申请号：EP17198552.6

    申请日：2017-10-26

    申请人： Acarix A/S

    发明人： SCHMIDT, Samuel Emil

    IPC分类号： A61B7/00 ,  A61B5/024

    摘要： The proposed technology relates to a method for indicating a risk for coronary artery disease. A sound recording is obtained (100) covering a plurality of heartbeats, a plurality of heart sounds are identified (200) in the sound recording, and a plurality of segments are obtained (300) from the sound recording. A frequency power measure is determined (400) based on the signal strength of a first frequency window of a period in the diastole, an amplitude of the fourth heart sound is determined (500) based on the plurality of heart sounds and the plurality of segments, and an indication of a heart rate variability is determined (600) based on the plurality of heart sounds. The indication of the risk for coronary artery disease is then determined (700) based on the frequency power measure, the amplitude of the fourth heart sound, and the indication of the heart rate variability.

    SYSTEM, STETHOSCOPE AND METHOD FOR INDICATING RISK OF CORONARY ARTERY DISEASE
    2.
    发明公开
    SYSTEM, STETHOSCOPE AND METHOD FOR INDICATING RISK OF CORONARY ARTERY DISEASE 有权
    系统，STETHOSKOP UND VERFAHREN ZUR ANZEIGE DES RISIKOS EINER KORONARARIIERERKRANKUNG

    公开(公告)号：EP2651304A1

    公开(公告)日：2013-10-23

    申请号：EP11794179.9

    申请日：2011-12-13

    申请人： Acarix A/S

    发明人： SCHMIDT, Samuel, Erik ,  STRUIJK, Johannes, Jan

    IPC分类号： A61B7/04 ,  G06F17/00

    摘要： The present invention relates to a system for detection of low frequency power for diagnosing of coronary artery disease (CAD), comprising: an acoustic sensor adapted to be placed on the chest of a patient, and to generate acoustic signals S A ; at least one memory adapted to store acoustic signals S A from the acoustic sensor; a control unit adapted to receive said acoustic signals S A ; the control unit further comprises: an identification unit adapted to identify diastolic or systolic periods in a predetermined time period of the stored acoustic signals S A , and to generate a period signal S P indicating said identified periods; a filtering unit adapted to apply at least one filter to said identified periods and to generate a low frequency band signal S LFB indicating low frequency bands of said identified periods; a calculation unit adapted to estimate the power in said low frequency band of said identified periods, to calculate a low frequency power measure based upon said estimated power and to generate a low frequency power measure signal S LFP indicating said low frequency power measure. The invention also relates to a stethoscope and a method for detection of low frequency power.

    摘要翻译： 本发明涉及用于诊断冠状动脉疾病（CAD）的低频功率检测系统，包括：适于放置在患者胸部上的声传感器，并产生声信号S A; 至少一个存储器，适于从声学传感器存储声学信号S A; 适于接收所述声信号S A的控制单元; 所述控制单元还包括：识别单元，其适于在所存储的声学信号S A的预定时间段中识别舒张期或收缩期，并且产生指示所述识别的周期的周期信号S P; 滤波单元，适于将至少一个滤波器应用于所述识别的周期，并产生指示所述识别的周期的低频带的低频带信号S LFB; 计算单元，其适于估计所述识别周期的所述低频带中的功率，以基于所述估计功率来计算低频功率测量，并产生指示所述低频功率测量的低频功率测量信号S LFP。 本发明还涉及一种用于检测低频功率的听诊器和方法。

    SYSTEM, STETHOSCOPE AND METHOD FOR INDICATING RISK OF CORONARY ARTERY DISEASE
    6.
    发明授权
    SYSTEM, STETHOSCOPE AND METHOD FOR INDICATING RISK OF CORONARY ARTERY DISEASE 有权

    公开(公告)号：EP2651304B1

    公开(公告)日：2020-05-27

    申请号：EP11794179.9

    申请日：2011-12-13

    申请人： Acarix A/S

    发明人： SCHMIDT, Samuel, Emil ,  STRUIJK, Johannes, Jan

    IPC分类号： A61B7/04 ,  G06F17/00

    摘要： The present invention relates to a system for detection of low frequency power for diagnosing of coronary artery disease (CAD), comprising: an acoustic sensor adapted to be placed on the chest of a patient, and to generate acoustic signals S A ; at least one memory adapted to store acoustic signals S A from the acoustic sensor; a control unit adapted to receive said acoustic signals S A ; the control unit further comprises: an identification unit adapted to identify diastolic or systolic periods in a predetermined time period of the stored acoustic signals S A , and to generate a period signal S P indicating said identified periods; a filtering unit adapted to apply at least one filter to said identified periods and to generate a low frequency band signal S LFB indicating low frequency bands of said identified periods; a calculation unit adapted to estimate the power in said low frequency band of said identified periods, to calculate a low frequency power measure based upon said estimated power and to generate a low frequency power measure signal S LFP indicating said low frequency power measure. The invention also relates to a stethoscope and a method for detection of low frequency power.

    QUANTITATIVE SEISMOCARDIOGRAPHY
    8.
    发明公开
    QUANTITATIVE SEISMOCARDIOGRAPHY 审中-公开
    定量心震颤

    公开(公告)号：EP3257441A1

    公开(公告)日：2017-12-20

    申请号：EP16174743.1

    申请日：2016-06-16

    申请人： Acarix A/S

    发明人： SCHMIDT, Samuel Emil ,  SØGAARD, Peter ,  STRUIJK, Johannes Jan

    IPC分类号： A61B5/11

    CPC分类号： A61B5/1102 ,  A61B5/02028 ,  A61B7/00 ,  A61B2562/0219

    摘要： A quantifying of the function of a beating heart is disclosed, in which a signal is recorded with an accelerometer placed on the chest of a person. A plurality of segments of the signal are formed, which are aligned and filtered with a band-pass filter having a lower cutoff frequency below 1 Hz and an upper cut-off frequency in the range 100-500 Hz. A mean segment is then determined, in which a first temporal feature is determined. A measure is then determined based on at least one of the signal strength of the first temporal feature and the location in time of the first temporal feature. The determined measure is then provided as output information.

    摘要翻译： 公开了一种量化跳动心脏的功能，其中用放置在人胸部上的加速度计记录信号。 形成多个信号段，其用具有低于1Hz的较低截止频率和在100-500Hz范围内的较高截止频率的带通滤波器对准和滤波。 然后确定平均段，其中确定第一时间特征。 然后基于第一时间特征的信号强度和第一时间特征的时间位置中的至少一个来确定测量。 然后将确定的量度作为输出信息提供。

    AUTOENCODERS IN QUANTITATIVE SEISMOCARDIOGRAPHY
    10.
    发明公开
    AUTOENCODERS IN QUANTITATIVE SEISMOCARDIOGRAPHY 审中-公开

    公开(公告)号：EP4306048A1

    公开(公告)日：2024-01-17

    申请号：EP22184623.1

    申请日：2022-07-13

    申请人： Acarix A/S

    发明人： SCHMIDT, Samuel Emil

    IPC分类号： A61B5/11 ,  A61B5/02 ,  A61B5/00

    摘要： A technology for determining an indication of heart failure of a subject (18) is proposed. It comprises: obtaining (100a) a first signal interval from a source signal recorded with an accelerometer (14) placed on the chest of a subject (18), wherein the first signal corresponds to a first subinterval of a heart cycle; inputting (200a) the first signal interval (36) into a first autoencoder, wherein the first autoencoder is trained on the corresponding first signal intervals obtained from healthy subjects and outputs a reconstructed first signal interval (44), determining (300a) a first correlation between the first signal interval (36) and the reconstructed first signal interval (44), and determining (400) the indication of heart failure based on the first correlation.