公开(公告)号：EP4085972A1

公开(公告)日：2022-11-09

申请号：EP21382415.4

申请日：2021-05-07

申请人： Consejo Superior de Investigaciones Científicas (CSIC) ,  Achucarro Basque Center for Neuroscience Fundazioa

发明人： FERNÁNDEZ DE SEVILLA GARCÍA-AGENJO, Estrella ,  TORRES ALEMÁN, Ignacio ,  PIGNATELLI GARRIGÓS, Jaime

IPC分类号： A61P25/00

摘要： The present invention relates to an AMP-activated protein kinase (AMPK) inhibitor or a pharmaceutical composition comprising said activator in a therapeutically effective amount for use in the treatment and/or prevention of post-traumatic stress disorder (PTSD) in a subject. It also relates to biomarkers of stress susceptibility and their use in a method to determine vulnerability to stress in a subject.

公开(公告)号：EP3817753A1

公开(公告)日：2021-05-12

申请号：EP19733831.2

申请日：2019-07-02

申请人： Universidad del País Vasco - Euskal Herriko Unibertsitatea ,  Achucarro Basque Center for Neuroscience Fundazioa

发明人： PINEDA MARTÍ, José Ramón ,  LUZURIAGA GONZÁLEZ, Jon ,  UNDA RODRÍGUEZ, Fernando ,  PASTOR ALONSO, Oier ,  ENCINAS PÉREZ, Juan Manuel ,  IBARRETXE BILBAO, Gaskon ,  IRASTORZA EPELDE, Igor

IPC分类号： A61K35/28 ,  C12N5/0775