-
公开(公告)号：EP2125777B1
公开(公告)日：2013-04-10
申请号：EP08730590.0
申请日：2008-02-24
发明人： CHEN, Guoqing, Paul
IPC分类号： C07D215/26 , C07D413/12 , A61K31/47 , A61P35/00
CPC分类号： C07D215/44 , C07D215/233 , C07D413/12
-
公开(公告)号：EP2125776B1
公开(公告)日：2017-07-05
申请号：EP08730589.2
申请日：2008-02-24
发明人： CHEN, Guoqing, Paul
IPC分类号： C07D401/02 , A61K31/47 , C07D403/02 , A61K31/517 , C07D401/12 , C07D239/74 , C07D239/88
CPC分类号： C07D401/12 , C07D239/74 , C07D239/88
-
公开(公告)号：EP2312950A1
公开(公告)日：2011-04-27
申请号：EP09808627.5
申请日：2009-08-13
发明人： CHEN, Guoqing, Paul
CPC分类号： A61K31/4709 , C07D401/12 , C07D401/14 , C07D405/14 , C07D491/113
摘要： The present invention relates to compounds of Formula (I), processes for their preparation, pharmaceutical compositions containing them as active ingredient, methods for the treatment of disease states associated with angiogenesis, such as cancers associated with protein tyrosine kinases, to their use as medicaments for use in the production of inhibition of tyrosine kinases reducing effects in warm-blooded animals such as humans.
-
公开(公告)号：EP2312950B1
公开(公告)日：2016-11-30
申请号：EP09808627.5
申请日：2009-08-13
发明人： CHEN, Guoqing, Paul
CPC分类号： A61K31/4709 , C07D401/12 , C07D401/14 , C07D405/14 , C07D491/113
-
公开(公告)号：EP2621904B1
公开(公告)日：2020-04-22
申请号：EP11824198.3
申请日：2011-09-09
发明人： CHEN, Guoqing, Paul
IPC分类号： C07D215/22 , C07D215/233 , C07D405/12 , A61K31/47 , A61K31/4709 , A61P35/00 , A61P29/00
-
公开(公告)号：EP2621904A2
公开(公告)日：2013-08-07
申请号：EP11824198.3
申请日：2011-09-09
发明人： CHEN, Guoqing, Paul
IPC分类号： C07D215/22 , C07D215/233 , C07D405/12 , A61K31/47 , A61K31/4709 , A61P35/00 , A61P29/00
CPC分类号： C07D215/22 , A61K31/47 , A61K31/4709 , C07D401/12 , C07D405/12 , C07D409/12
摘要： The present invention relates to compounds, processes for their preparation, pharmaceutical compositions containing them as active ingredient, methods for the treatment of disease states associated with the inhibition of the protein tyrosine kinase activity of growth factor receptors such as c-Met, thereby making them useful as anticancer agents, to their use as medicaments for use in the production of inhibition of tyrosine kinases reducing effects in warmblooded animals such as humans.
-
公开(公告)号：EP2125777A1
公开(公告)日：2009-12-02
申请号：EP08730590.0
申请日：2008-02-24
发明人： CHEN, Guoqing, Paul
IPC分类号： C07D401/02 , A61K31/47 , C07D403/02 , A61K31/517
CPC分类号： C07D215/44 , C07D215/233 , C07D413/12
摘要： (I) The present invention relates to spiro (tetracarbon) substituted compound of Formula I, processes for their preparation, pharmaceutical compositions containing them as active ingredient, methods for the treatment of disease states associated with angiogenesis, such as cancers associated with protein tyrosine kinases, to their use as medicaments for use in the production of inhibition of tyrosine kinases reducing effects in warm-blooded animals such as humans.
-
公开(公告)号：EP2125776A1
公开(公告)日：2009-12-02
申请号：EP08730589.2
申请日：2008-02-24
发明人： CHEN, Guoqing, Paul
IPC分类号： C07D401/02 , A61K31/47 , C07D403/02 , A61K31/517
CPC分类号： C07D401/12 , C07D239/74 , C07D239/88
摘要： (I) The present invention relates to spiro (tetracarbon) substituted compound of Formula I, processes for their preparation, pharmaceutical compositions containing them as active ingredient, methods for the treatment of disease states associated with angiogenesis, such as cancers associated with protein tyrosine kinases, to their use as medicaments for use in the production of inhibition of tyrosine kinases reducing effects in warm-blooded animals such as humans.
摘要翻译： （I）本发明涉及式（I）的螺（四羰基）取代的化合物，其制备方法，含有它们作为活性成分的药物组合物，治疗与血管生成有关的疾病状态的方法，例如与蛋白酪氨酸激酶有关的癌症 涉及它们作为药物用于抑制酪氨酸激酶在温血动物例如人中的作用。
-
-
-
-
-
-
-
搜索结果
8 条记录 (耗时 0.011 秒)
