公开(公告)号：EP1756139A2

公开(公告)日：2007-02-28

申请号：EP05736385.5

申请日：2005-03-11

申请人： EntreMed, Inc. ,  Agoston, Gregory E. ,  Shah, Jamshed, H.

发明人： AGOSTON, Gregory, E. ,  SHAH, Jamshed, H. ,  SUWANDI, Lita ,  LAVALLEE, Theresa, M. ,  TRESTON, Anthony

IPC分类号： C07J1/00 ,  C07J11/00 ,  A61K31/56

CPC分类号： C07J1/00

摘要： Compositions and methods for treating mammalian diseases or conditions characterized by undesirable angiogenesis by administering an effective amount of a compound of the formula I (I), or formula II (II), wherein Ra is selected from -OCH3, OCH2CH3 or -CCCH3; and Z is selected from >C(H)-OH, >C(H)-O-alkyl, >C(H)-O-sulfamate, where alkyl is a linear, branched and/or cyclic hydrocarbon chain comprising 1 to 10 carbons.

公开(公告)号：EP1756139A4

公开(公告)日：2009-07-29

申请号：EP05736385

申请日：2005-03-11

申请人： ENTREMED INC ,  AGOSTON GREGORY E ,  SHAH JAMSHED H

发明人： AGOSTON GREGORY E ,  SHAH JAMSHED H ,  SUWANDI LITA ,  LAVALLEE THERESA M ,  TRESTON ANTHONY

IPC分类号： C07J1/00 ,  A61K31/56 ,  C07J11/00

CPC分类号： C07J1/00