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    PAPP-A2 AS A MARKER FOR MONITORING, PREDICTING AND DIAGNOSING PREECLAMPSIA
    1.
    发明公开
    PAPP-A2 AS A MARKER FOR MONITORING, PREDICTING AND DIAGNOSING PREECLAMPSIA 审中-公开
    PAPP-A2为指标进行监测，预测及先兆子痫的诊断

    公开(公告)号：EP2890816A4

    公开(公告)日：2016-06-15

    申请号：EP13834143

    申请日：2013-08-30

    申请人： ANSH LABS LLC

    发明人： KUMAR AJAY ,  OXVIG CLAUS ,  SAVJANI GOPAL V

    IPC分类号： C12Q1/68 ,  G01N33/53 ,  G01N33/567

    CPC分类号： G01N33/689 ,  G01N2800/368 ,  G01N2800/50

    摘要： PAPP-A2 is used as a marker for monitoring, predicting and diagnosing preeclampsia in pregnant women. PAPP-A2 levels in pregnant women with preeclampsia are higher than PAPP-A2 levels in normal pregnant women. This is especially true of PAPP-A2 levels that are measured later on in the pregnancy. PAPP-A2 levels may be measured early in pregnancy in order to predict the likelihood of the patient having preeclampsia. Preeclampsia may also be diagnosed at later gestational ages when the levels of PAPP-A2 are more pronounced than normal PAPP-A2 levels at the same gestational age. The present invention relates to methods of assessing, predicting and diagnosing preeclampsia as well as a kit-of-parts for assessing, predicting and diagnosing preeclampsia.

    PAPP-A2 AS A MARKER FOR MONITORING, PREDICTING AND DIAGNOSING PREECLAMPSIA
    3.
    发明公开
    PAPP-A2 AS A MARKER FOR MONITORING, PREDICTING AND DIAGNOSING PREECLAMPSIA 审中-公开
    PAPP-A2为指标进行监测，预测及先兆子痫的诊断

    公开(公告)号：EP2890816A2

    公开(公告)日：2015-07-08

    申请号：EP13834143.3

    申请日：2013-08-30

    申请人： Ansh Labs LLC

    发明人： KUMAR, Ajay ,  OXVIG, Claus ,  SAVJANI, Gopal, V.

    IPC分类号： C12Q1/68 ,  G01N33/53 ,  G01N33/567

    CPC分类号： G01N33/689 ,  G01N2800/368 ,  G01N2800/50

    摘要： PAPP-A2 is used as a marker for monitoring, predicting and diagnosing preeclampsia in pregnant women. PAPP-A2 levels in pregnant women with preeclampsia are higher than PAPP-A2 levels in normal pregnant women. This is especially true of PAPP-A2 levels that are measured later on in the pregnancy. PAPP-A2 levels may be measured early in pregnancy in order to predict the likelihood of the patient having preeclampsia. Preeclampsia may also be diagnosed at later gestational ages when the levels of PAPP-A2 are more pronounced than normal PAPP-A2 levels at the same gestational age. The present invention relates to methods of assessing, predicting and diagnosing preeclampsia as well as a kit-of- parts for assessing, predicting and diagnosing preeclampsia.

    ANTIBODY COMPOSITIONS AND IMMUNOASSAY METHODS TO DETECT ISOFORMS OF ANTI-MULLERIAN HORMONE
    4.
    发明公开
    ANTIBODY COMPOSITIONS AND IMMUNOASSAY METHODS TO DETECT ISOFORMS OF ANTI-MULLERIAN HORMONE 审中-公开
    抗体组合物和免疫分析方法检测抗-MUELLER激素的亚型

    公开(公告)号：EP2917235A2

    公开(公告)日：2015-09-16

    申请号：EP13853068.8

    申请日：2013-11-08

    申请人： Ansh Labs LLC

    发明人： GOPAL, V., Savjani ,  AJAY, Kumar

    IPC分类号： C07K16/00 ,  G01N33/00 ,  A61K39/395

    CPC分类号： G01N33/74 ,  C07K16/26 ,  G01N33/6863 ,  G01N2333/575

    摘要： Disclosed are compositions and methods for detecting and quantifying human anti- Mtillerian hormone (AMH) in biological samples. In particular, the invention provides novel methods of measuring different forms of AMH in a biological sample, such as human plasma The anti-AMH antibody compositions disclosed herein enable reproducible measurement and quantitation of AMH, including dimeric forms of the AMH protein and fragments thereof. The antibody compositions disclosed herein find particular utility as diagnostic tools for single epitope sandwich-based AMH assays, which can be used to diagnose a variety of medical conditions.