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公开(公告)号：EP3515947A1
公开(公告)日：2019-07-31
申请号：EP17769050.0
申请日：2017-09-18
发明人： WILMEN, Andreas , BUCHMÜLLER, Anja , TUCKER, Erik
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公开(公告)号：EP4413996A2
公开(公告)日：2024-08-14
申请号：EP24166025.7
申请日：2017-09-18
发明人： WILMEN, Andreas , BUCHMÜLLER, Anja , TUCKER, Erik
IPC分类号： A61K39/00
CPC分类号： A61K2039/50520130101 , C07K2317/2420130101 , C07K2317/3320130101 , C07K2317/56520130101 , C07K2317/7620130101 , C07K2317/9220130101 , C07K16/36 , A61P7/02
摘要： The present invention in general relates to novel binding molecules, in particular antibodies and compositions and kits comprising the same. Said binding molecules are capable of binding to human Factor XI and hence envisaged to be particularly useful in inhibiting thrombosis without compromising hemostasis. The binding molecules, compositions and kits provided herein are therefore inter alia intended for treatment of thrombosis-related diseases and conditions. Moreover, polynucleotides encoding the binding molecules of the invention, vectors comprising said polynucleotides and host cells for producing the polynucleotides are provided herein.
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