公开(公告)号：EP1504780A1

公开(公告)日：2005-02-09

申请号：EP03721098.6

申请日：2003-05-13

申请人： Bioactis Limited ,  Tsutsui, Tatsuo

发明人： TSUTSUI, Tatsuo;

IPC分类号： A61M13/00 ,  A61M15/08

CPC分类号： A61M15/0028 ,  A61M15/0038 ,  A61M15/004 ,  A61M15/08 ,  A61M2202/064 ,  A61M2205/075

摘要： In a device to deliver a powdery medicine into a nasal cavity, one-way valve 33 is built in an air flow passage 31 of a capsule housing/holding part 30, the one-way valve 33 is controlled for the opening pressure by a spring 34 and opens by a pressure of air from the pump 50, the one-way valve end 71 does not interfere the setting/detaching operation of the capsule setting/detaching part 40 and the capsule K when the one-way valve 33 is opened and intrudes as far as the inside of the capsule to disperse the medicine in the capsule K when the one-way valve 33 is opened by pressing of the pump 50 upon dosing thereby capable of reliably dosing at a adequate dose also including the medicine falling as far as the one-way valve 33 to the nasal cavity of the user.

摘要翻译： 在将粉末药物输送到鼻腔的装置中，单向阀33内置在胶囊容纳部30的气流通道31中，单向阀33通过弹簧被控制开启压力 34，并且通过来自泵50的空气压力打开时，单向阀端部71在单向阀33打开时不干扰胶囊安装/拆卸部件40和胶囊K的设置/拆卸操作， 当通过在给药时按压泵50打开单向阀33时能将胶囊K内的药剂分散到胶囊K中，从而能够以足够的剂量可靠地定量给药，还包括掉在远处的药物 作为使用者鼻腔的单向阀33。

公开(公告)号：EP1607117A1

公开(公告)日：2005-12-21

申请号：EP03715528.0

申请日：2003-03-27

申请人： Bioactis Limited

发明人： TSUTSUI, Tatsuo

IPC分类号： A61M13/00

CPC分类号： A61M15/0028 ,  A61M13/00 ,  A61M15/0038 ,  A61M15/0041 ,  A61M2202/064 ,  A61M2205/075

摘要： Improvement for the device to deliver the powdery medicine into nasal cavities in which a capsule setting/detaching part 40 is built drawably in the capsule housing/holding part 30, and cutting blades 60A, 60B are built in both axial ends of the capsule setting/detaching part 40 of the capsule housing/holding part 30 for cutting both axial ends of the capsule thereby perforating the capsule. A medicine capturing/collecting part 32 and a one-way valve 33 are built in a lower portion of the capsule housing/holding part 30, and a pump 50 having an air inlet valve 54 is built in the air flow inlet side thereof. A medicine delivery part 20 is built in the air exit of the capsule housing/holding part 30, a nozzle 22 is installed and medicine in the capsule can be dosed to the nasal cavities of the user by pressing the pump 50.

摘要翻译： 用于将粉末药物输送到鼻腔中的改进，其中胶囊设置/分离部件40可抽吸地建立在胶囊壳体/保持部件30中，以及切割刀片60A，60B被构建在胶囊设置/ 拆卸胶囊壳体/保持部分30的部分40，以切割胶囊的两个轴向端部，从而使胶囊穿孔。 药剂收集部32和单向阀33内置在胶囊容纳部30的下部，并且在其空气流入口侧内置有具有进气阀54的泵50。 药剂输送部20内置在胶囊容纳部30的空气出口内，安装喷嘴22，通过按压泵50将胶囊内的药剂配给使用者的鼻腔。

公开(公告)号：EP1671667A1

公开(公告)日：2006-06-21

申请号：EP03754055.6

申请日：2003-10-09

申请人： Bioactis Limited

发明人： TSUTSUI, Tatsuo

IPC分类号： A61M13/00

CPC分类号： A61M15/0028 ,  A61M15/003 ,  A61M15/0038 ,  A61M15/004 ,  A61M15/08 ,  A61M2202/064 ,  A61M2205/075

摘要： In a device to deliver a powdery medicine for a nasal cavity of the invention, positioning guides 12a, 12b for causing a capsule to slide as far as a predetermined position is placed on this side of cutters 11a, 11b for making holes on both ends of the capsule loaded between the connection port 7 on the side of a nozzle for spraying the powdery medicine into a nasal cavity and a connection port 8 on the side of a pump for supplying spray air to the nozzle in order to make the size of the holes made on both ends of the capsule 4 constant, and a distance L between the connection ports 7 and 8 is made shorter than a distance M between blade tips of the cutters 11a and 11b (length of the capsule 4 after cutting off the both ends by the cutters 11a, 11b), for preventing scattering of the powdery medicine in the capsule from both ends of the capsule 4 loaded between the connection ports 7 and 8, so that both ends of the capsule 4 loaded between the connection ports 7 and 8 are pressed by peripheral edges 14, 15 of the connection ports 7, 8.

摘要翻译： 在用于输送本发明的鼻腔粉末药物的装置中，用于使胶囊滑动到预定位置的定位引导件12a，12b被放置在刀具11a，11b的两侧用于在 胶囊装载在用于将粉末药物喷射到鼻腔的喷嘴侧的连接口7和用于向喷嘴供给喷射空气的泵侧的连接口8之间，以使孔的尺寸 在胶囊4的两端形成一个恒定的连接口7和8之间的距离L比刀具11a和11b的刀尖之间的距离M短（切断两端之后的胶囊4的长度 切割器11a，11b），用于防止从装载在连接端口7和8之间的胶囊4两端的胶囊中的粉末药物散射，使得装载在连接端口7和8之间的胶囊4的两端为 按 连接端口7,8的外围边缘14,15。

公开(公告)号：EP1504822A1

公开(公告)日：2005-02-09

申请号：EP03723343.4

申请日：2003-05-13

申请人： Bioactis Limited

发明人： Tsutsui, Tatsuo, Atsugi-Mouridai Diamond Mansion

IPC分类号： B05B9/04 ,  B65D83/44

CPC分类号： F16K1/303 ,  B65D83/48

摘要： A gas injection valve designed for long-term storage of liquefied carbon dioxide, adapted to minimize the permeation of carbon gas through a seal ring even if used for a long time, thus solving the problems including an increase in injection concentration of the contents and a decrease in the number of times of spraying. Particularly, it is arranged that a seal ring (17) closely contacts the three surfaces of a seal ring holding groove (18) holding the seal ring (17), and the outer peripheral surface of a valve pin, whereby the gas permeation area of the seal ring (17) is reduced to a half or less of the conventional valve. Further, the seal ring (17) is made of an elastic material whose carbon dioxide gas permeability is low, thereby greatly reducing the amount of gas permeation through the seal ring (17).

摘要翻译： 一种设计用于长期储存液化二氧化碳的气体注入阀，其适用于尽可能减少碳气通过密封环的渗透，即使长时间使用，从而解决了包括增加内容物的注入浓度和 喷雾次数减少。 特别地，密封环（17）紧密接触保持密封环（17）的密封环保持槽（18）和阀销的外周面的三个表面，由此气体渗透面积 密封环（17）减小到常规阀的一半或更小。 此外，密封环17由二氧化碳气体渗透性低的弹性材料制成，从而大大减少通过密封环17的气体渗透量。