公开(公告)号：EP1727789A2

公开(公告)日：2006-12-06

申请号：EP05708731.4

申请日：2005-03-10

申请人： Pfizer Limited ,  Brown, Alan Daniel

发明人： BROWN, Alan Daniel Pfizer Global Res.and Developm ,  BUNNAGE, Mark, Edward Pfizer Global Res.and Devel. ,  GLOSSOP, Paul, Alan Pfizer Global Res.and Develop. ,  JAMES, Kim Pfizer Global Research and Development ,  LANE, Charlotte, Alice, Luise Pfizer Global Res. ,  LEWTHWAITE, Russell, Andrew Pfizer Global Res.and ,  LUNN, Graham Pfizer Global Research and Develop. ,  PRICE, David, Anthony Pfizer Global Res.and Devel.

IPC分类号： C07C237/20 ,  C07D217/06 ,  A61K31/165 ,  A61K31/472

CPC分类号： C07D217/06

摘要： The invention relates to compounds of formula (1) and to processes for the preparation of, intermediates used in the preparation of, compositions containing and the uses of, such derivatives. The compounds according to the present invention are useful in numerous diseases, disorders and conditions, in particular inflammatory, allergic and respiratory diseases, disorders and conditions.

摘要翻译： 本发明涉及式（1）的化合物和用于制备用于制备含有这些衍生物和其用途的组合物的中间体的方法。 根据本发明的化合物可用于多种疾病，病症和病症，特别是炎性，变应性和呼吸系统疾病，病症和病症。

公开(公告)号：EP1758910A1

公开(公告)日：2007-03-07

申请号：EP05741010.2

申请日：2005-05-27

申请人： Pfizer Limited ,  Brown, Alan Daniel

发明人： BROWN, Alan Daniel ,  CALABRESE, Andrew, Antony ,  ELLIS, David ,  WATSON, Lesa

IPC分类号： C07D498/04 ,  C07D498/14 ,  C07D471/14 ,  A61K31/551 ,  A61K31/553 ,  A61P15/00

CPC分类号： C07D471/14 ,  C07D487/14 ,  C07D498/04

摘要： This invention relates to compounds of formula (I) with activity as oxytocin antagonists, uses thereof, processes for the preparation thereof and compositions containing said inhibitors. These inhibitors have utility in a variety of therapeutic areas including sexual dysfunction, particularly premature ejaculation (P.E.).

公开(公告)号：EP1611097A1

公开(公告)日：2006-01-04

申请号：EP04715968.6

申请日：2004-03-01

申请人： Pfizer Limited ,  Brown, Alan Daniel

发明人： BROWN, Alan Daniel, Pfizer Central R&D ,  BRYANS, Justin Stephen, Pfizer Global R&D ,  BUNNAGE, Mark Edward, Pfizer Global R&D ,  GLOSSOP, Paul Alan, Pfizer Global R&D ,  LANE, Charlotte Alice Louise, Pfizer Global R&D ,  LEWTHWAITE, Russell Andrew, Pfizer Global R&D ,  MANTELL, Simon John, Pfizer Global R&D

IPC分类号： C07D209/42 ,  C07D401/12 ,  C07D417/12 ,  A61K31/40 ,  A61P3/00

CPC分类号： C07D209/42 ,  C07D401/12 ,  C07D417/12

摘要： The invention relates to indole derivatives of formula (I) and to processes for the preparation of, intermediates used in the preparation of, compositions containing and the uses of, such derivatives. The indole derivatives according to the present invention are useful in numerous diseases, disorders and conditions, in particular inflammatory, allergic and respiratory diseases, disorders and conditions.