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公开(公告)号：EP4403901A1
公开(公告)日：2024-07-24
申请号：EP23382034.9
申请日：2023-01-17
申请人： Fundacio Institut de Bioenginyeria de Catalunya , Institució Catalana de Recerca I Estudis Avançats , Akademia Gorniczo-Hutnicza im. Stanislawa Staszica w Krakowie
IPC分类号： G01N21/552
CPC分类号： G01N21/554
摘要： The present invention relates generally to the field of biosensors, and in particular the present invention provides a two-step method that can be applied to any 1-2D nanocrystal template for metaplasmonic biosensing in order to enhance the surface sensitivity for biorecognition events below 100 nm, preferably between 10 to 15 nm.
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公开(公告)号：EP4419206A1
公开(公告)日：2024-08-28
申请号：EP22808742.5
申请日：2022-10-21
申请人： Fundacio Institut de Bioenginyeria de Catalunya , Fundación Privada Instituto De Salud Global Barcelona , Universitat de Barcelona
发明人： FERNÀNDEZ BUSQUETS, Xavier , BIOSCA ROMANILLOS, Arnau , BOUZÓN ARNÁIZ, Inés , MUÑOZ-TORRERO LÓPEZ-IBARRA, Diego , MARTÍNEZ ARCE, Elsa , REOLID COLL, Pau
IPC分类号： A61P33/06 , C07D213/38 , C07D401/14 , A61K31/4427
CPC分类号： C07D213/38 , C07D401/14 , A61P33/06 , Y02A50/30
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3.发明授权
公开(公告)号：EP3423098B1
公开(公告)日：2020-05-06
申请号：EP17715525.6
申请日：2017-03-01
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4.发明公开
公开(公告)号：EP4098252A1
公开(公告)日：2022-12-07
申请号：EP21386032.3
申请日：2021-06-02
申请人： Université de Liège , Fundacio Institut de Bioenginyeria de Catalunya , Barcelona Institute For Global Health , Foundation For Research And Technology Hellas
发明人： Grandfils, Christian , Sevrin, Chantal , Fernàndez Busquets, Xavier , Siden-Kiamos, Inga , Vontas, John
IPC分类号： A61K9/16 , A61K31/121 , A61K31/122 , A61K31/167 , A61P43/00
摘要： The invention provides a complex comprising at least one hydrophobic active agent, an ionic polymer comprising a repetitive unit of formula (I):
wherein R 1 represents a hydrogen atom or a straight or branched chain alkyl group, preferably a straight or branched chain alkyl group comprising from 1 to 6 carbon atoms, for example a methyl group; R 2 represents a straight or branched chain alkyl group which is substituted by a group which may have a positive charge at a physiological pH; a complex for use in a method of medical treatment; a pharmaceutical composition; and a method of preparing a complex according to the invention which method comprises the steps of:
(a) dissolving the hydrophobic active agent and the ionic polymer in one or more non-aqueous solvents to form the complex wherein the one or more non-aqueous solvents are miscible with water; and
(b) progressively replacing the one or more non-aqueous solvents with water.-
5.发明公开
公开(公告)号：EP3945313A1
公开(公告)日：2022-02-02
申请号：EP20382702.7
申请日：2020-07-30
申请人： Fundacio Institut de Bioenginyeria de Catalunya , Universitat de Barcelona , Consorcio Centro de Investigación Biomédica en Red M.P.
发明人： SAMITIER MARTÍ, Josep , MIR LLORENTE, Mònica , DULAY BACENA, Samuel , RIVAS TORCATES, Lourdes Josefina , MISERERE, Sandrine , PÉREZ LÓPEZ, Briza , LOPEZ DE MIGUEL, Manuel , PALACIO BONET, Francisco
IPC分类号： G01N27/416 , G01N27/49
摘要： An electrochemical sensor system for sensing analytical reactions and biological operations is provided. The electrochemical sensor system comprises: an amperometric sensor comprising two electrodes, wherein the electrodes comprise a working electrode and a reference electrode, wherein the amperometric sensor includes no other electrodes and a potentiometric sensor comprising a working electrode and a reference electrode, wherein the potentiometric sensor includes no other electrodes, wherein the reference electrode of the potentiometric sensor is coupled to ground, wherein the working electrode of the amperometric sensor is electrically coupled to the reference electrode of the potentiometric sensor, wherein the amperometric sensor is configured to receive an excitation voltage between the working electrode of the amperometric sensor and the reference electrode of the amperometric sensor such that the received excitation voltage is used as a reference voltage of the potentiometric sensor via the reference electrode of the potentiometric sensor.
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