专利检索 ap:"INSERM INST NAT DE LA SANTÉ ET DE LA RECH MÉDICALE" 第 1 页

1.

发明公开
RECOMBINANT MYCOBACTERIUM ENCODING A HEPARIN-BINDING HEMAGGLUTININ (HBHA) FUSION PROTEIN AND USES THEREOF 审中-公开
标题翻译：重组结核分枝编码肝素结合血细胞凝集素（HBHA）的融合蛋白及其用途

公开(公告)号：EP2838990A4

公开(公告)日：2016-08-10

申请号：EP12874533

申请日：2012-04-16

申请人： AERAS GLOBAL TB VACCINE FOUND , INSERM INST NAT DE LA SANTÉ ET DE LA RECH MÉDICALE

发明人： FULKERSON JOHN , BRENNAN MICHAEL , VELMURUGAN KAMALAKANNAN , LOCHT CAMILLE

IPC分类号： C12N1/21 , A61K39/00 , A61K39/04 , A61K49/00 , C07K14/35 , C07K19/00 , C12N15/62 , C12P21/00

CPC分类号： C07K14/35 , A61K39/04 , A61K49/0006 , A61K2039/523 , A61K2039/53 , C07K2319/00 , C07K2319/02 , C07K2319/40 , C07K2319/90

摘要： Recombinant Mycobacteria (rMyc) which contain sequences encoding a heparin-binding hemagglutinin (HBHA) fusion protein are provided, as are methods of making and using the rMyc and the fusion protein. The fusion protein includes an amino terminal mycobacterial antigen Ag85B leader peptide and transcription of the fusion protein is driven by an Ag85B promoter sequence. The recombinant fusion protein is produced in abundance by the rMyc, is post-translationally methylated, and is highly antigenic.

2.

发明公开
NUCLEIC ACID CONSTRUCT INCLUDING NUCLEIC ACID DERIVED FROM GENOTYPE 3a HCV GENOME 审中-公开
标题翻译： WITH获得的核酸基因型3A-HCV的基因组的核酸构建

公开(公告)号：EP2752485A4

公开(公告)日：2015-06-24

申请号：EP12827627

申请日：2012-08-31

申请人： JAPAN AS REPRESENTED BY THE DIRECTOR GENERAL OF NAT INST OF INFECTIOUS DISEASES , INSERM INST NAT DE LA SANTÉ ET DE LA RECH MÉDICALE , TORAY INDUSTRIES

发明人： WAKITA TAKAJI , SAEED MOHSAN , MAUREL PATRICK , GONDEAU CLAIRE , YOKOKAWA HIROSHI

IPC分类号： C12N15/09 , A61K39/29 , C07K16/10 , C12N5/10 , C12N7/00 , C12Q1/02 , C12Q1/68

CPC分类号： C07K14/005 , C07K16/109 , C12N7/00 , C12N2770/24221 , C12N2770/24222 , C12N2770/24234 , C12Q1/18 , G01N33/5008 , G01N33/5767 , G01N2333/186