公开(公告)号：EP2467176A4

公开(公告)日：2014-04-16

申请号：EP10810658

申请日：2010-08-20

申请人： MALSHE AJAY P ,  JIANG WENPING

发明人： MALSHE AJAY P ,  JIANG WENPING

IPC分类号： A61L27/32 ,  A61L27/30 ,  A61L27/56

CPC分类号： A61L27/306 ,  A61L27/32 ,  A61L27/56 ,  A61L2400/12 ,  Y10T428/24413 ,  Y10T428/24893 ,  Y10T428/24997

公开(公告)号：EP2467176B1

公开(公告)日：2017-04-05

申请号：EP10810658.4

申请日：2010-08-20

申请人： Malshe, Ajay P. ,  Jiang, Wenping

发明人： Malshe, Ajay P. ,  Jiang, Wenping

IPC分类号： A61L27/32 ,  A61L27/30 ,  A61L27/56

CPC分类号： A61L27/306 ,  A61L27/32 ,  A61L27/56 ,  A61L2400/12 ,  Y10T428/24413 ,  Y10T428/24893 ,  Y10T428/24997

公开(公告)号：EP2467176A1

公开(公告)日：2012-06-27

申请号：EP10810658.4

申请日：2010-08-20

申请人： Malshe, Ajay P. ,  Jiang, Wenping

发明人： Malshe, Ajay P. ,  Jiang, Wenping

IPC分类号： A61L27/32

CPC分类号： A61L27/306 ,  A61L27/32 ,  A61L27/56 ,  A61L2400/12 ,  Y10T428/24413 ,  Y10T428/24893 ,  Y10T428/24997

摘要： A high-strength coating for dental and orthopedic implants utilizing hydroxyapatite (HAp) nanoparticles provides for a high level of osseointegration through a range of surface pore sizes in the micro- to nanoscale. Zinc oxide (ZnO) nanoparticles may be incorporated with the HAp nanoparticles to form a composite coating material, with ZnO providing infection resistance due to its inherent antimicrobial properties. A textured surface, consisting of "islands" of roughly square coating structures measuring about 250μm on a side, with spacing of 50-1 OOμm therebetween, may further promote the osseointegration and antimicrobial properties of the implant coating.