公开(公告)号：EP2809410B1

公开(公告)日：2016-01-20

申请号：EP12703449.4

申请日：2012-02-02

申请人： LDA AG

发明人： WIESBECK, Franz

IPC分类号： C07D311/40 ,  C07D311/62 ,  C08B37/00 ,  B01D11/02

CPC分类号： C08B37/006 ,  B01D11/0219 ,  C07D311/40 ,  C07D311/62

公开(公告)号：EP2809310B1

公开(公告)日：2016-01-20

申请号：EP12703448.6

申请日：2012-02-02

申请人： LDA AG

发明人： WIESBECK, Franz

IPC分类号： C07D311/62 ,  A61K36/15 ,  B01D9/00 ,  B01D11/02

CPC分类号： C07D311/62 ,  A61K36/15 ,  A61K2236/00 ,  B01D9/0036 ,  B01D11/0219

公开(公告)号：EP2809410A1

公开(公告)日：2014-12-10

申请号：EP12703449.4

申请日：2012-02-02

申请人： LDA AG

发明人： WIESBECK, Franz

IPC分类号： B01D11/02 ,  C07D311/00

CPC分类号： C08B37/006 ,  B01D11/0219 ,  C07D311/40 ,  C07D311/62

摘要： The invention relates to a method for an extraction from wood, having the following steps: providing wood particles of at least one first class and wood particles of a second class, stacking a fine layer consisting of the wood particles of the first class over another layer consisting of the wood particles of the second class, and extracting the wood particles using a liquid extracting agent. The extracting agent flows from top to bottom first through the fine layer and then through the other layer. The wood particles of the first class are finer than the wood particles of the second class, and thus the fine layer has a lower permeability that the other layer.

公开(公告)号：EP2809310A1

公开(公告)日：2014-12-10

申请号：EP12703448.6

申请日：2012-02-02

申请人： LDA AG

发明人： WIESBECK, Franz

IPC分类号： A61K31/085 ,  A61K31/352 ,  A61K36/15 ,  B01D9/00 ,  B01D11/02

CPC分类号： C07D311/62 ,  A61K36/15 ,  A61K2236/00 ,  B01D9/0036 ,  B01D11/0219

摘要： The invention relates to a method for producing taxifolin, having the following steps: stacking wood particles in a percolator; extracting the wood particles in the percolator using ethanol in order to dissolve at least resins, oils, and taxifolin; conducting the ethanol extract out of the percolator; and purifying the ethanol extract in order to produce taxifolin using the following steps in the given sequence: producing a mixture of water and the ethanol extract; mixing the mixture at 70 °C to 99 °C such that the taxifolin dissolves in the water phase of the mixture; cooling the mixture to below 65°C in order to separate and conduct the resin phase and the oil phase from the water phase; adding taxifolin seed crystals to the water phase; controlling the temperature of the water phase to 0 °C to 30 °C in order to crystallize the taxifolin; and separating the crystallized taxifolin from the mother liquor.